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UniProtKB/Swiss-Prot entry Q2GKK3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRB_ANAPZ
Primary accession number Q2GKK3
Secondary accession numbers None
Integrated into Swiss-Prot on September 11, 2007
Sequence was last modified on March 21, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 23)
Name and origin of the protein
Protein name Aspartate carbamoyltransferase
Synonyms EC 2.1.3.2
Aspartate transcarbamylase
ATCase
Gene name
Name: pyrB
OrderedLocusNames: APH_0503
From
Anaplasma phagocytophilum (strain HZ) [TaxID: 212042] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Anaplasmataceae; Anaplasma; phagocytophilum group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0020021; PubMed=16482227 [NCBI, ExPASy, EBI, Israel, Japan]
Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V., Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M., Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N., Nelson W.C., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J.P., Daugherty S.C., Davidsen T., Durkin A.S., Gwinn M.L., Haft D.H., Selengut J.D., Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R., Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H.;
"Comparative genomics of emerging human ehrlichiosis agents.";
PLoS Genet. 2:208-222(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000235; ABD43862.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_505098.1; -.
3D structure databases
ModBase Q2GKK3.
Enzyme and pathway databases
BioCyc APHA212042:APH_0503-MON; -.
Ontologies
GO
GO:0004070; Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00001; -; 1.
PBIL [Tree]
InterPro IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.
Pfam PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.
PRINTS PR00100; AOTCASE.
PR00101; ATCASE.
TIGRFAMs TIGR00670; asp_carb_tr; 1.
PROSITE PS00097; CARBAMOYLTRANSFERASE; 1.
BLOCKS Q2GKK3.
Genome annotation databases
GeneID 3930392; -.
GenomeReviews CP000235_GR; APH_0503.
KEGG aph:APH_0503; -.
NMPDR fig|212042.5.peg.497; -.
TIGR APH_0503; -.
Phylogenomic databases
HOGENOM Q2GKK3; -.
Other
ProtoNet Q2GKK3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Pyrimidine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   300  300     Aspartate carbamoyltransferase. PRO_0000301550
Sequence information
Length: 300 AA [This is the length of the unprocessed precursor] Molecular weight: 32821 Da [This is the MW of the unprocessed precursor] CRC64: 6C5CF10F6B738A66 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKKLNKLLRI QSLSDVDIEN IVALAHRYLQ DSSANNVLQG RVIANLFFEN STRTLLAFEI 

        70         80         90        100        110        120 
AEKSLGAVSV TLNVETSSMK KGESVSDTLS TLSAMGVDLV VVRSGFSGFI DEVVERVGDC 

       130        140        150        160        170        180 
CVINAGDGNH EHPTQALTDY ATIRYLKGKY IEGLNVTICG DIFHSRVARS NMRLLSRYGA 

       190        200        210        220        230        240 
NINVVTPPCW SASVPSSNVT KITHSLEEGI KDADVIMLLR IQKERMSGAS FISANEYSRH 

       250        260        270        280        290        300 
YMLDNAKLSI AKDDVIIMHP GPMNRGIEIS DEVADASSSI LLQVKMGVAV RKAILHYMLG 

Q2GKK3 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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