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UniProtKB/Swiss-Prot entry Q29RH3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NUD12_BOVIN
Primary accession number Q29RH3
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on April 4, 2006 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 19)
Name and origin of the protein
Protein name Peroxisomal NADH pyrophosphatase NUDT12
Synonyms EC 3.6.1.22
Nucleoside diphosphate-linked moiety X motif 12
Nudix motif 12
Gene name
Name: NUDT12
From
Bos taurus (Bovine) [TaxID: 9913] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=Hereford;
TISSUE=Heart ventricle;
NIH - Mammalian Gene Collection (MGC) project;
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC114173; AAI14174.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_001040073.1; -.
UniGene Bt.17805
3D structure databases
ModBase Q29RH3.
Ontologies
GO
GO:0005777; Cellular component: peroxisome (inferred from electronic annotation from UniProtKB-KW).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0030145; Molecular function: manganese ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0000210; Molecular function: NAD+ diphosphatase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR002110; ANK.
IPR015375; NADH_PPase-like_N.
IPR000086; NUDIX_hydrolase_core.
IPR015376; Znr_NADH_PPase.
Graphical view of domain structure.
Gene3D G3DSA:1.25.40.20; ANK; 1.
G3DSA:3.90.79.10; NUDIX_hydrolase; 1.
Pfam PF00293; NUDIX; 1.
PF09296; NUDIX-like; 1.
PF09297; zf-NADH-PPase; 1.
Pfam graphical view of domain structure.
PRINTS PR00502; NUDIXFAMILY.
PROSITE PS50297; ANK_REP_REGION; FALSE_NEG.
PS50088; ANK_REPEAT; FALSE_NEG.
PS00893; NUDIX; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet Q29RH3.
Genome annotation databases
GeneID 617720; -.
KEGG bta:617720; -.
Phylogenomic databases
HOVERGEN Q29RH3; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ANK repeat; Hydrolase; Magnesium; Manganese; Metal-binding; NAD; NADP; Peroxisome; Repeat.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   444  444     Peroxisomal NADH pyrophosphatase NUDT12. PRO_0000260768
REPEAT   11    40  30     ANK 1. 
REPEAT   60    80  21     ANK 2. 
MOTIF   337   358  22     Nudix box (By similarity). 
MOTIF   442   444  3     Microbody targeting signal (By similarity). 
METAL   352   352        Magnesium or manganese (By similarity). 
METAL   356   356        Magnesium or manganese (By similarity). 
Sequence information
Length: 444 AA [This is the length of the unprocessed precursor] Molecular weight: 50119 Da [This is the MW of the unprocessed precursor] CRC64: D9352B6AFCD6F21B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSSVKRSLNQ EIISQFHYSA AEGDIAKLTA ILSHSPSLLN ETSENGWSAL ICDRSIVNKS 

        70         80         90        100        110        120 
RQTALDIAKF WGYKHIANLL ANAKGGKKPW FLTNEVEECE NYFSKTLLDR KSEKRNNSDW 

       130        140        150        160        170        180 
LLAKESHPAT VYILFSDLNP LVTLGGNKES FQQPEVRLCQ LNYTDIKDYL AQPEKITLIF 

       190        200        210        220        230        240 
LGVELEMKKE FFNYAGEISK EEEDGLVAWF ALGIDTVAAE EFKQRHENCY FLHPPMPALL 

       250        260        270        280        290        300 
QLKEKEAGVV AQARSVLAWH SRYKFCPTCG NATKIEEGGY KRVCLKEDCP SLHGVHNTSY 

       310        320        330        340        350        360 
PRVDPVVIMQ VIHPDGTKCL LGRQKRFPPG MFTCLAGFIE PGETIEDAVR REVEEESGVK 

       370        380        390        400        410        420 
VGHVQYVSCQ PWPMPSSLMI GCLAVAVSTE IKVDKNEIED ARWFTREQVV DVLTKGKQQA 

       430        440 
FFVPPSRAIA HQLIKHWIGM NPNL
Q29RH3 in FASTA format

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