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UniProtKB/Swiss-Prot entry Q17761

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_CAEEL
Primary accession number Q17761
Secondary accession number Q22772
Integrated into Swiss-Prot on October 25, 2005
Sequence was last modified on November 1, 1998 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 59)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
ORFNames: T25B9.9
From
Caenorhabditis elegans [TaxID: 6239] 
Taxonomy Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan]
The C. elegans sequencing consortium;
"Genome sequence of the nematode C. elegans: a platform for investigating biology.";
Science 282:2012-2018(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z70311; CAA94380.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z70306; CAA94380.1; JOINED; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z70306; CAA94326.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z70311; CAA94326.1; JOINED; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T19020; T19020.
RefSeq NP_501998.1; -.
UniGene Cel.6711
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase Q17761.
Organism-specific databases
WormBase WBGene00012015; T25B9.9.
WormPep T25B9.9; CE06508. [WormPep / WorfDB]
Gene expression databases
ArrayExpress Q17761; -.
Ontologies
GO
GO:0009792; Biological process: embryonic development ending in birth or egg hatching (inferred from mutant phenotype from WormBase).
GO:0018996; Biological process: molting cycle, collagen and cuticulin-based cuticle (inferred from mutant phenotype from WormBase).
GO:0002119; Biological process: nematode larval development (inferred from mutant phenotype from WormBase).
QuickGo view.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS Q17761.
Genome annotation databases
Ensembl T25B9.9; Caenorhabditis elegans. [Contig view]
GeneID 177971; -.
KEGG cel:T25B9.9; -.
Other
ProtoNet Q17761.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   484  484     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090067
Sequence information
Length: 484 AA [This is the length of the unprocessed precursor] Molecular weight: 53196 Da [This is the MW of the unprocessed precursor] CRC64: D3CF6F1065F17535 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAEADIAVIG LAVMGQNLIL NMNDHGFTVC AFNRTVKLVD DFLANEAKGT KIIGAHSIEE 

        70         80         90        100        110        120 
MCKKLKRPRR VMMLIKAGTP VDMMIDAIVP HLEEGDIIID GGNSEYTDSN RRSEQLAAKG 

       130        140        150        160        170        180 
IMFVGCGVSG GEEGARFGPS LMPGGNPKAW PHLKDIFQKI AAKSNGEPCC DWVGNAGSGH 

       190        200        210        220        230        240 
FVKMVHNGIE YGDMQLIAEA YHLLSKAVEL NHDQMAEVLD DWNKGELESF LIEITANILK 

       250        260        270        280        290        300 
YRDEQGEPIV PKIRDSAGQK GTGKWTCFAA LEYGLPVTLI GEAVFARCLS ALKDERVRAS 

       310        320        330        340        350        360 
KQLPRPQVSP DTVVQDKRVF IKQISKALYA SKIVSYAQGF MLLAEASKQF NWNLNFGAIA 

       370        380        390        400        410        420 
LMWRGGCIIR SRFLGDIEHA FQKNKQLSNL LLDDFFTKAI TEAQDSWRVV VCAAVRLGIP 

       430        440        450        460        470        480 
VPAFSSALAF YDGYTSEVVP ANLLQAQRDY FGAHTYELLA KPGTWVHTNW TGTGGRVTSN 


AYNA
Q17761 in FASTA format

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