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UniProtKB/Swiss-Prot entry Q16AV0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SYK_ROSDO
Primary accession number Q16AV0
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on July 25, 2006 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 25)
Name and origin of the protein
Protein name Lysyl-tRNA synthetase
Synonyms EC 6.1.1.6
Lysine--tRNA ligase
LysRS
Gene name
Name: lysS
OrderedLocusNames: RD1_1246
From
Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) [TaxID: 375451] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales; Rhodobacteraceae; Roseobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01390-06; PubMed=17098896 [NCBI, ExPASy, EBI, Israel, Japan]
Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J., Ramos H., Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C., Shah M.K., O'Huallachain M.E., Lince M.T., Blankenship R.E., Beatty J.T., Touchman J.W.;
"The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism.";
J. Bacteriol. 189:683-690(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000362; ABG30893.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_681579.1; -.
3D structure databases
ModBase Q16AV0.
Enzyme and pathway databases
BioCyc RDEN375451:RD1_1246-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-SubCell).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004824; Molecular function: lysine-tRNA ligase activity (inferred from electronic annotation from HAMAP).
GO:0006430; Biological process: lysyl-tRNA aminoacylation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00177; -; 1.
PBIL [Tree]
InterPro IPR008925; aa-tRNA-synth_I_codon-bd.
IPR001412; aa-tRNA-synth_I_CS.
IPR002904; Lys-tRNA-synth_Ic_arc-type.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
G3DSA:1.10.10.350; tRNA_synt_bd; 1.
Pfam PF01921; tRNA-synt_1f; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00467; lysS_arch; 1.
PROSITE PS00178; AA_TRNA_LIGASE_I; 1.
Genome annotation databases
GeneID 4197453; -.
GenomeReviews CP000362_GR; RD1_1246.
KEGG rde:RD1_1246; -.
NMPDR fig|375451.6.peg.1163; -.
Phylogenomic databases
HOGENOM Q16AV0; -.
OMA Q16AV0; AFSDDMD.
Genome annotation databases
CMR Q16AV0; RD1_1246.
Other
ProtoNet Q16AV0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Protein biosynthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   527  527     Lysyl-tRNA synthetase. PRO_1000040354
MOTIF   44    52  9     "HIGH" region. 
MOTIF   290   294  5     "KMSKS" region. 
BINDING   293   293        ATP (By similarity). 
Sequence information
Length: 527 AA [This is the length of the unprocessed precursor] Molecular weight: 59384 Da [This is the MW of the unprocessed precursor] CRC64: 23D33C5964D04CA1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSDTRTAAMT SKAWPFEEAR RVLKRYEKNP PEKGYVLFET GYGPSGLPHI GTFGEVARTS 

        70         80         90        100        110        120 
MVMRAFQEIS DIPTRLICFS DDLDGMRKVP GNVPNPDALT EHLQRPLTSV PDPFGTHASF 

       130        140        150        160        170        180 
GAHNNAMLRR FLDTFGFEYE FISATEFYNT GQFDEILLRA AAKYDEIMAV MLKSLREERR 

       190        200        210        220        230        240 
QTYSIFLPIH PESGRVMYVP MKEVNAQAGT ITFDSEDGEE MTLPVTGGAV KLQWKPDFGA 

       250        260        270        280        290        300 
RWAALGVDFE MYGKDHSTNT PIYDKICRIL GQRPPEHFTY ELFLDENGQK ISKSSGNGVS 

       310        320        330        340        350        360 
IDEWLTYAST ESLSYFMYQK PKTAKRMYFD VIPKAVDEYH QQLRAYAGQD TAQRLNNPVW 

       370        380        390        400        410        420 
HIHGGDVPAS NMLVPFSMLL NLASVSSAED KSQLWGFIQR YAPESNPENN PDMDAAADFA 

       430        440        450        460        470        480 
VRYFNDFVKP KKVYRAASDL EREALEDLRD QLKAYDGPVD DEALQSIVYA CGRERFDPLR 

       490        500        510        520 
GWFTALYEVL LGASQGPRFG GFIALYGVQE TVALIDAALA GELLSDD
Q16AV0 in FASTA format

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