[1]
|
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
TISSUE=Placenta;
DOI=10.1073/pnas.93.9.4278; PubMed=8633055 [NCBI, ExPASy, EBI, Israel, Japan]
Liu C.-G.,
Maercker C.,
Castanon M.J.,
Hauptmann R.,
Wiche G.;
"Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24).";
Proc. Natl. Acad. Sci. U.S.A. 93:4278-4283(1996).
|
[2]
|
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 2 AND 3), AND DISEASE.
PubMed=8698233 [NCBI, ExPASy, EBI, Israel, Japan]
McLean W.H.I.,
Pulkkinen L.,
Smith F.J.D.,
Rugg E.L.,
Lane E.B.,
Bullrich F.,
Burgeson R.E.,
Amano S.,
Hudson D.L.,
Owaribe K.,
McGrath J.A.,
McMillan J.R.,
Eady R.A.J.,
Leigh I.M.,
Christiano A.M.,
Uitto J.;
"Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization.";
Genes Dev. 10:1724-1735(1996).
|
[3]
|
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 4; 5; 6; 7; 8 AND 9).
DOI=10.1101/gr.1225204; PubMed=14672974 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang T.,
Haws P.,
Wu Q.;
"Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.";
Genome Res. 14:79-89(2004).
|
[4]
|
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature04406; PubMed=16421571 [NCBI, ExPASy, EBI, Israel, Japan]
Nusbaum C.,
Mikkelsen T.S.,
Zody M.C.,
Asakawa S.,
Taudien S.,
Garber M.,
Kodira C.D.,
Schueler M.G.,
Shimizu A.,
Whittaker C.A.,
Chang J.L.,
Cuomo C.A.,
Dewar K.,
FitzGerald M.G.,
Yang X.,
Allen N.R.,
Anderson S.,
Asakawa T.,
Blechschmidt K., ![]()
Bloom T.,
Borowsky M.L.,
Butler J.,
Cook A.,
Corum B.,
DeArellano K.,
DeCaprio D.,
Dooley K.T.,
Dorris L. III,
Engels R.,
Gloeckner G.,
Hafez N.,
Hagopian D.S.,
Hall J.L.,
Ishikawa S.K.,
Jaffe D.B.,
Kamat A.,
Kudoh J.,
Lehmann R.,
Lokitsang T.,
Macdonald P.,
Major J.E.,
Matthews C.D.,
Mauceli E.,
Menzel U.,
Mihalev A.H.,
Minoshima S.,
Murayama Y.,
Naylor J.W.,
Nicol R.,
Nguyen C.,
O'Leary S.B.,
O'Neill K.,
Parker S.C.J.,
Polley A.,
Raymond C.K.,
Reichwald K.,
Rodriguez J.,
Sasaki T.,
Schilhabel M.,
Siddiqui R.,
Smith C.L.,
Sneddon T.P.,
Talamas J.A.,
Tenzin P.,
Topham K.,
Venkataraman V.,
Wen G.,
Yamazaki S.,
Young S.K.,
Zeng Q.,
Zimmer A.R.,
Rosenthal A.,
Birren B.W.,
Platzer M.,
Shimizu N.,
Lander E.S.;
"DNA sequence and analysis of human chromosome 8.";
Nature 439:331-335(2006).
|
[5]
|
PROTEIN SEQUENCE OF 14-21; 209-227; 237-248; 301-316; 329-336; 350-365; 372-417; 510-517; 588-597; 631-675; 697-706; 714-724; 734-740; 751-764; 857-869; 897-908; 927-934; 1029-1037; 1045-1052; 1076-1088; 1131-1139; 1166-1175; 1187-1210; 1216-1224; 1227-1243; 1251-1266; 1274-1291; 1318-1335; 1338-1344; 1351-1364; 1366-1382; 1411-1438; 1473-1479; 1499-1508; 1554-1563; 1596-1603; 1606-1616; 1628-1638; 1649-1657; 1671-1679; 1699-1709; 1732-1744; 1783-1792; 1825-1833; 1846-1854; 1867-1875; 1888-1908; 1976-1994; 2006-2014; 2048-2055; 2058-2068; 2079-2087; 2098-2108; 2130-2139; 2142-2150; 2172-2182; 2199-2217; 2310-2316; 2319-2329; 2340-2348; 2361-2379; 2402-2409; 2420-2429; 2432-2442; 2462-2473; 2483-2503; 2512-2521; 2565-2575; 2587-2594; 2651-2663; 2685-2693; 2705-2761; 2768-2787; 2795-2821; 2833-2841; 2847-2881; 2885-2903; 2942-2968; 2979-3007; 3028-3039; 3045-3053; 3095-3106; 3109-3127; 3132-3139; 3146-3154; 3175-3183; 3213-3231; 3244-3259; 3270-3285; 3289-3297; 3317-3335; 3356-3368; 3374-3384; 3424-3436; 3447-3469; 3477-3485; 3506-3513; 3519-3540; 3544-3568; 3601-3637; 3648-3661; 3667-3676; 3686-3702; 3739-3749; 3771-3781; 3784-3804; 3839-3878; 3887-3897; 3926-3963; 3969-3999; 4004-4018; 4027-4060; 4084-4091; 4122-4138; 4159-4167; 4179-4205; 4278-4296; 4339-4348; 4354-4360; 4384-4401; 4429-4447; 4467-4475; 4492-4500; 4543-4551; 4590-4627 AND 4668-4684, PHOSPHORYLATION AT SER-4385, AND MASS SPECTROMETRY.
TISSUE=Ovarian carcinoma;
Bienvenut W.V.,
Lilla S.,
von Kriegsheim A.,
Lempens A.,
Kolch W.;
Submitted (DEC-2008) to UniProtKB.
|
[6]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-720; SER-1435; SER-4386; THR-4402; SER-4613 AND THR-4623, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1073/pnas.0404720101; PubMed=15302935 [NCBI, ExPASy, EBI, Israel, Japan]
Beausoleil S.A.,
Jedrychowski M.,
Schwartz D.,
Elias J.E.,
Villen J.,
Li J.,
Cohn M.A.,
Cantley L.C.,
Gygi S.P.;
"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
|
[7]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1721; SER-4386 AND SER-4389, AND MASS SPECTROMETRY.
DOI=10.1021/pr050048h; PubMed=16083285 [NCBI, ExPASy, EBI, Israel, Japan]
Kim J.-E.,
Tannenbaum S.R.,
White F.M.;
"Global phosphoproteome of HT-29 human colon adenocarcinoma cells.";
J. Proteome Res. 4:1339-1346(2005).
|
[8]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-4611, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1074/mcp.M500089-MCP200; PubMed=15951569 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang Y.,
Wolf-Yadlin A.,
Ross P.L.,
Pappin D.J.,
Rush J.,
Lauffenburger D.A.,
White F.M.;
"Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.";
Mol. Cell. Proteomics 4:1240-1250(2005).
|
[9]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-4615, AND MASS SPECTROMETRY.
DOI=10.1038/nbt1046; PubMed=15592455 [NCBI, ExPASy, EBI, Israel, Japan]
Rush J.,
Moritz A.,
Lee K.A.,
Guo A.,
Goss V.L.,
Spek E.J.,
Zhang H.,
Zha X.-M.,
Polakiewicz R.D.,
Comb M.J.;
"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.";
Nat. Biotechnol. 23:94-101(2005).
|
[10]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-782, AND MASS SPECTROMETRY.
TISSUE=Hepatocyte;
DOI=10.1002/pmic.200401217; PubMed=16097034 [NCBI, ExPASy, EBI, Israel, Japan]
Gevaert K.,
Staes A.,
Van Damme J.,
De Groot S.,
Hugelier K.,
Demol H.,
Martens L.,
Goethals M.,
Vandekerckhove J.;
"Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.";
Proteomics 5:3589-3599(2005).
|
[11]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-125; SER-149; SER-720; SER-1435; SER-1721; THR-2814; THR-4030; SER-4382; SER-4384; SER-4385; SER-4386; THR-4411 AND SER-4620, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21 (ISOFORM 4), AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
|
[12]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1435; SER-4384; SER-4396; SER-4613 AND SER-4620, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21 (ISOFORM 4), AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1073/pnas.0507066103; PubMed=16565220 [NCBI, ExPASy, EBI, Israel, Japan]
Nousiainen M.,
Sillje H.H.W.,
Sauer G.,
Nigg E.A.,
Koerner R.;
"Phosphoproteome analysis of the human mitotic spindle.";
Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
|
[13]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-3362 AND TYR-4155, AND MASS SPECTROMETRY.
DOI=10.1016/j.cell.2007.11.025; PubMed=18083107 [NCBI, ExPASy, EBI, Israel, Japan]
Rikova K.,
Guo A.,
Zeng Q.,
Possemato A.,
Yu J.,
Haack H.,
Nardone J.,
Lee K.,
Reeves C.,
Li Y.,
Hu Y.,
Tan Z.,
Stokes M.,
Sullivan L.,
Mitchell J.,
Wetzel R.,
Macneill J.,
Ren J.M.,
Yuan J., ![]()
Bakalarski C.E.,
Villen J.,
Kornhauser J.M.,
Smith B.,
Li D.,
Zhou X.,
Gygi S.P.,
Gu T.-L.,
Polakiewicz R.D.,
Rush J.,
Comb M.J.;
"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.";
Cell 131:1190-1203(2007).
|
[14]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1435, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21 (ISOFORM 4), AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1021/pr070152u; PubMed=17924679 [NCBI, ExPASy, EBI, Israel, Japan]
Yu L.-R.,
Zhu Z.,
Chan K.C.,
Issaq H.J.,
Dimitrov D.S.,
Veenstra T.D.;
"Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
J. Proteome Res. 6:4150-4162(2007).
|
[15]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1644 AND SER-2755, AND MASS SPECTROMETRY.
DOI=10.1126/science.1140321; PubMed=17525332 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuoka S.,
Ballif B.A.,
Smogorzewska A.,
McDonald E.R. III,
Hurov K.E.,
Luo J.,
Bakalarski C.E.,
Zhao Z.,
Solimini N.,
Lerenthal Y.,
Shiloh Y.,
Gygi S.P.,
Elledge S.J.;
"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.";
Science 316:1160-1166(2007).
|
[16]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4386, AND MASS SPECTROMETRY.
DOI=10.1021/pr0705441; PubMed=18220336 [NCBI, ExPASy, EBI, Israel, Japan]
Cantin G.T.,
Yi W.,
Lu B.,
Park S.K.,
Xu T.,
Lee J.-D.,
Yates J.R. III;
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.";
J. Proteome Res. 7:1346-1351(2008).
|
[17]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-125; SER-720 AND SER-1435, AND MASS SPECTROMETRY.
DOI=10.1016/j.molcel.2008.07.007; PubMed=18691976 [NCBI, ExPASy, EBI, Israel, Japan]
Daub H.,
Olsen J.V.,
Bairlein M.,
Gnad F.,
Oppermann F.S.,
Korner R.,
Greff Z.,
Keri G.,
Stemmann O.,
Mann M.;
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.";
Mol. Cell 31:438-448(2008).
|
[18]
|
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-125; SER-149; SER-720; SER-1435; SER-1732; THR-4030; SER-4382; SER-4384; SER-4385; SER-4386; SER-4389; SER-4392; TYR-4393; SER-4396; SER-4613; SER-4622; THR-4623; SER-4626; THR-4628; SER-4642 AND SER-4658, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0805139105; PubMed=18669648 [NCBI, ExPASy, EBI, Israel, Japan]
Dephoure N.,
Zhou C.,
Villen J.,
Beausoleil S.A.,
Bakalarski C.E.,
Elledge S.J.,
Gygi S.P.;
"A quantitative atlas of mitotic phosphorylation.";
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
|
[19]
|
IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
|
[20]
|
X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) OF 409-640.
DOI=10.1016/j.jmb.2007.02.090; PubMed=17397861 [NCBI, ExPASy, EBI, Israel, Japan]
Sonnenberg A.,
Rojas A.M.,
de Pereda J.M.;
"The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain.";
J. Mol. Biol. 368:1379-1391(2007).
|
[21]
|
X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 159-403.
DOI=10.1016/S0969-2126(03)00090-X; PubMed=12791251 [NCBI, ExPASy, EBI, Israel, Japan]
Garcia-Alvarez B.,
Bobkov A.,
Sonnenberg A.,
de Pereda J.M.;
"Structural and functional analysis of the actin binding domain of plectin suggests alternative mechanisms for binding to F-actin and integrin beta4.";
Structure 11:615-625(2003).
|
[22]
|
VARIANT MD-EBS 1003-GLN--ALA-1005 DEL.
DOI=10.1093/hmg/5.10.1539; PubMed=8894687 [NCBI, ExPASy, EBI, Israel, Japan]
Pulkkinen L.,
Smith F.J.D.,
Shimizu H.,
Murata S.,
Yaoita H.,
Hachisuka H.,
Nishikawa T.,
McLean W.H.I.,
Uitto J.;
"Homozygous deletion mutations in the plectin gene (PLEC1) in patients with epidermolysis bullosa simplex associated with late-onset muscular dystrophy.";
Hum. Mol. Genet. 5:1539-1546(1996).
|
[23]
|
VARIANT MD-EBS LEU-429 INS.
PubMed=11159198 [NCBI, ExPASy, EBI, Israel, Japan]
Bauer J.W.,
Rouan F.,
Kofler B.,
Rezniczek G.A.,
Kornacker I.,
Muss W.,
Hametner R.,
Klausegger A.,
Huber A.,
Pohla-Gubo G.,
Wiche G.,
Uitto J.,
Hintner H.;
"A compound heterozygous one amino-acid insertion/nonsense mutation in the plectin gene causes epidermolysis bullosa simplex with plectin deficiency.";
Am. J. Pathol. 158:617-625(2001).
|
[24]
|
VARIANT O-EBS TRP-2110.
DOI=10.1046/j.0022-202x.2001.01591.x; PubMed=11851880 [NCBI, ExPASy, EBI, Israel, Japan]
Koss-Harnes D.,
Hoeyheim B.,
Anton-Lamprecht I.,
Gjesti A.,
Joergensen R.S.,
Jahnsen F.L.,
Olaisen B.,
Wiche G.,
Gedde-Dahl T. Jr.;
"A site-specific plectin mutation causes dominant epidermolysis bullosa simplex Ogna: two identical de novo mutations.";
J. Invest. Dermatol. 118:87-93(2002).
|
[25]
|
INVOLVEMENT IN EBS-PA.
DOI=10.1111/j.1523-1747.2003.12639.x; PubMed=14675180 [NCBI, ExPASy, EBI, Israel, Japan]
Charlesworth A.,
Gagnoux-Palacios L.,
Bonduelle M.,
Ortonne J.-P.,
De Raeve L.,
Meneguzzi G.;
"Identification of a lethal form of epidermolysis bullosa simplex associated with a homozygous genetic mutation in plectin.";
J. Invest. Dermatol. 121:1344-1348(2003).
|
|
ExPASy Home page
SIB Switzerland
