[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INTERACTION WITH BCL2 AND BCL2L1/BCLXL, AND SUBCELLULAR LOCATION.
DOI=10.1038/ncb894; PubMed=12510191 [NCBI, ExPASy, EBI, Israel, Japan]
Shirane M.,
Nakayama K.I.;
"Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis.";
Nat. Cell Biol. 5:28-37(2003).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
Bulgakov O.V.,
Eggenschwiler J.T.,
Hong D.-H.,
Anderson K.V.,
Li T.;
"FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues.";
Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
TISSUE=Colon endothelium;
Bloecker H.,
Boecher M.,
Mewes H.-W.,
Weil B.,
Amid C.,
Osanger A.,
Fobo G.,
Han M.,
Wiemann S.;
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature02399; PubMed=15057824 [NCBI, ExPASy, EBI, Israel, Japan]
Grimwood J.,
Gordon L.A.,
Olsen A.S.,
Terry A.,
Schmutz J.,
Lamerdin J.E.,
Hellsten U.,
Goodstein D.,
Couronne O.,
Tran-Gyamfi M.,
Aerts A.,
Altherr M.,
Ashworth L.,
Bajorek E.,
Black S.,
Branscomb E.,
Caenepeel S.,
Carrano A.V.,
Caoile C., ![]()
Chan Y.M.,
Christensen M.,
Cleland C.A.,
Copeland A.,
Dalin E.,
Dehal P.,
Denys M.,
Detter J.C.,
Escobar J.,
Flowers D.,
Fotopulos D.,
Garcia C.,
Georgescu A.M.,
Glavina T.,
Gomez M.,
Gonzales E.,
Groza M.,
Hammon N.,
Hawkins T.,
Haydu L.,
Ho I.,
Huang W.,
Israni S.,
Jett J.,
Kadner K.,
Kimball H.,
Kobayashi A.,
Larionov V.,
Leem S.-H.,
Lopez F.,
Lou Y.,
Lowry S.,
Malfatti S.,
Martinez D.,
McCready P.M.,
Medina C.,
Morgan J.,
Nelson K.,
Nolan M.,
Ovcharenko I.,
Pitluck S.,
Pollard M.,
Popkie A.P.,
Predki P.,
Quan G.,
Ramirez L.,
Rash S.,
Retterer J.,
Rodriguez A.,
Rogers S.,
Salamov A.,
Salazar A.,
She X.,
Smith D.,
Slezak T.,
Solovyev V.,
Thayer N.,
Tice H.,
Tsai M.,
Ustaszewska A.,
Vo N.,
Wagner M.,
Wheeler J.,
Wu K.,
Xie G.,
Yang J.,
Dubchak I.,
Furey T.S.,
DeJong P.,
Dickson M.,
Gordon D.,
Eichler E.E.,
Pennacchio L.A.,
Richardson P.,
Stubbs L.,
Rokhsar D.S.,
Myers R.M.,
Rubin E.M.,
Lucas S.M.;
"The DNA sequence and biology of human chromosome 19.";
Nature 428:529-535(2004).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J.,
Istrail S.,
Sutton G.G.,
Florea L.,
Halpern A.L.,
Mobarry C.M.,
Lippert R.,
Walenz B.,
Shatkay H.,
Dew I.,
Miller J.R.,
Flanigan M.J.,
Edwards N.J.,
Bolanos R.,
Fasulo D.,
Halldorsson B.V.,
Hannenhalli S.,
Turner R.,
Yooseph S., ![]()
Lu F.,
Nusskern D.R.,
Shue B.C.,
Zheng X.H.,
Zhong F.,
Delcher A.L.,
Huson D.H.,
Kravitz S.A.,
Mouchard L.,
Reinert K.,
Remington K.A.,
Clark A.G.,
Waterman M.S.,
Eichler E.E.,
Adams M.D.,
Hunkapiller M.W.,
Myers E.W.,
Venter J.C.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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[6]
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NUCLEOTIDE SEQUENCE [MRNA] OF 35-412 (ISOFORM 1).
DOI=10.1016/0378-1119(95)00216-S; PubMed=7543869 [NCBI, ExPASy, EBI, Israel, Japan]
Lam E.,
Martin M.,
Wiederrecht G.;
"Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs.";
Gene 160:297-302(1995).
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[7]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 42-412 (ISOFORM 2).
TISSUE=Liver;
Suzuki Y.,
Sugano S.,
Totoki Y.,
Toyoda A.,
Takeda T.,
Sakaki Y.,
Tanaka A.,
Yokoyama S.;
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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[8]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 54-412 (ISOFORM 1).
TISSUE=Pancreas;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[9]
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FUNCTION, AND SUBCELLULAR LOCATION.
DOI=10.1016/j.bbrc.2005.09.023; PubMed=16176796 [NCBI, ExPASy, EBI, Israel, Japan]
Kang C.B.,
Feng L.,
Chia J.,
Yoon H.S.;
"Molecular characterization of FK-506 binding protein 38 and its potential regulatory role on the anti-apoptotic protein Bcl-2.";
Biochem. Biophys. Res. Commun. 337:30-38(2005).
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[10]
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PPIASE ACTIVITY, AND COFACTOR.
DOI=10.1038/sj.emboj.7600739; PubMed=15990872 [NCBI, ExPASy, EBI, Israel, Japan]
Edlich F.,
Weiwad M.,
Erdmann F.,
Fanghaenel J.,
Jarczowski F.,
Rahfeld J.-U.,
Fischer G.;
"Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin.";
EMBO J. 24:2688-2699(2005).
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[11]
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FUNCTION, AND ABSENCE OF DIRECT INTERACTION WITH CALCINEURIN.
DOI=10.1016/j.febslet.2004.12.098; PubMed=15757646 [NCBI, ExPASy, EBI, Israel, Japan]
Weiwad M.,
Edlich F.,
Erdmann F.,
Jarczowski F.,
Kilka S.,
Dorn M.,
Pechstein A.,
Fischer G.;
"A reassessment of the inhibitory capacity of human FKBP38 on calcineurin.";
FEBS Lett. 579:1591-1596(2005).
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[12]
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INTERACTION WITH BCL2.
DOI=10.1016/j.febslet.2005.01.053; PubMed=15733859 [NCBI, ExPASy, EBI, Israel, Japan]
Kang C.B.,
Tai J.,
Chia J.,
Yoon H.S.;
"The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38).";
FEBS Lett. 579:1469-1476(2005).
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[13]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-322, AND MASS SPECTROMETRY.
DOI=10.1038/nbt1046; PubMed=15592455 [NCBI, ExPASy, EBI, Israel, Japan]
Rush J.,
Moritz A.,
Lee K.A.,
Guo A.,
Goss V.L.,
Spek E.J.,
Zhang H.,
Zha X.-M.,
Polakiewicz R.D.,
Comb M.J.;
"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.";
Nat. Biotechnol. 23:94-101(2005).
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[14]
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INTERACTION WITH BCL2.
DOI=10.1074/jbc.M606181200; PubMed=17090549 [NCBI, ExPASy, EBI, Israel, Japan]
Portier B.P.,
Taglialatela G.;
"Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression.";
J. Biol. Chem. 281:40493-40502(2006).
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[15]
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INTERACTION WITH HCV NS5A.
DOI=10.1016/j.febslet.2006.07.002; PubMed=16844119 [NCBI, ExPASy, EBI, Israel, Japan]
Wang J.,
Tong W.,
Zhang X.,
Chen L.,
Yi Z.,
Pan T.,
Hu Y.,
Xiang L.,
Yuan Z.;
"Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells.";
FEBS Lett. 580:4392-4400(2006).
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[16]
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STRUCTURE BY NMR OF 92-210.
DOI=10.1007/s10858-006-0018-6; PubMed=16604427 [NCBI, ExPASy, EBI, Israel, Japan]
Maestre-Martinez M.,
Edlich F.,
Jarczowski F.,
Weiwad M.,
Fischer G.,
Luecke C.;
"Solution structure of the FK506-binding domain of human FKBP38.";
J. Biomol. NMR 34:197-202(2006).
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[17]
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STRUCTURE BY NMR OF 91-205.
RIKEN structural genomics initiative (RSGI);
"Solution structure of RUH-047, an FKBP domain from human cDNA.";
Submitted (JUN-2006) to the PDB data bank.
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[18]
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X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 90-205.
Structural genomics consortium (SGC);
"Structure of the human FK-506 binding protein 8.";
Submitted (OCT-2006) to the PDB data bank.
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