[1]
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NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH EIF4E, AND PHOSPHORYLATION.
TISSUE=Placenta;
DOI=10.1038/371762a0; PubMed=7935836 [NCBI, ExPASy, EBI, Israel, Japan]
Pause A.,
Belsham G.J.,
Gingras A.-C.,
Donze O.,
Lin T.-A.,
Lawrence J.C. Jr.,
Sonenberg N.;
"Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function.";
Nature 371:762-767(1994).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
Ito M.,
Shichijo S.,
Tsuda N.,
Ochi M.,
Harashima N.,
Saito N.,
Itoh K.;
"Identification of multiple genes and immunogenic epitopes of pancreatic cancer cells.";
Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Kalnine N.,
Chen X.,
Rolfs A.,
Halleck A.,
Hines L.,
Eisenstein S.,
Koundinya M.,
Raphael J.,
Moreira D.,
Kelley T.,
LaBaer J.,
Lin Y.,
Phelan M.,
Farmer A.;
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector.";
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Ebert L.,
Schick M.,
Neubert P.,
Schatten R.,
Henze S.,
Korn B.;
"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201).";
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Colon, and Lung;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan] The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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PROTEIN SEQUENCE OF 2-13, AND ACETYLATION AT SER-2.
TISSUE=Platelet;
DOI=10.1038/nbt810; PubMed=12665801 [NCBI, ExPASy, EBI, Israel, Japan]
Gevaert K.,
Goethals M.,
Martens L.,
Van Damme J.,
Staes A.,
Thomas G.R.,
Vandekerckhove J.;
"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.";
Nat. Biotechnol. 21:566-569(2003).
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[7]
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INTERACTION WITH EIF4E AND EIF4G.
PubMed=8521827 [NCBI, ExPASy, EBI, Israel, Japan]
Haghighat A.,
Mader S.,
Pause A.,
Sonenberg N.;
"Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E.";
EMBO J. 14:5701-5709(1995).
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[8]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
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[9]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-46, AND MASS SPECTROMETRY.
DOI=10.1002/elps.200600782; PubMed=17487921 [NCBI, ExPASy, EBI, Israel, Japan]
Giorgianni F.,
Zhao Y.,
Desiderio D.M.,
Beranova-Giorgianni S.;
"Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.";
Electrophoresis 28:2027-2034(2007).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65; THR-70; SER-94 AND SER-101, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0611217104; PubMed=17287340 [NCBI, ExPASy, EBI, Israel, Japan]
Molina H.,
Horn D.M.,
Tang N.,
Mathivanan S.,
Pandey A.;
"Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.";
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
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[11]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-112, AND MASS SPECTROMETRY.
DOI=10.1126/science.1140321; PubMed=17525332 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuoka S.,
Ballif B.A.,
Smogorzewska A.,
McDonald E.R. III,
Hurov K.E.,
Luo J.,
Bakalarski C.E.,
Zhao Z.,
Solimini N.,
Lerenthal Y.,
Shiloh Y.,
Gygi S.P.,
Elledge S.J.;
"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.";
Science 316:1160-1166(2007).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65 AND THR-68, AND MASS SPECTROMETRY.
DOI=10.2116/analsci.24.161; PubMed=18187866 [NCBI, ExPASy, EBI, Israel, Japan]
Imami K.,
Sugiyama N.,
Kyono Y.,
Tomita M.,
Ishihama Y.;
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Anal. Sci. 24:161-166(2008).
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[13]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35; THR-36; THR-37; THR-41; THR-46; THR-50; THR-70; THR-82; SER-83; SER-94 AND SER-101, AND MASS SPECTROMETRY.
DOI=10.1021/pr0705441; PubMed=18220336 [NCBI, ExPASy, EBI, Israel, Japan]
Cantin G.T.,
Yi W.,
Lu B.,
Park S.K.,
Xu T.,
Lee J.-D.,
Yates J.R. III;
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.";
J. Proteome Res. 7:1346-1351(2008).
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[14]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-37; THR-41; THR-46; THR-50; TYR-54; SER-65; THR-70; THR-77; SER-83 AND SER-94, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0805139105; PubMed=18669648 [NCBI, ExPASy, EBI, Israel, Japan]
Dephoure N.,
Zhou C.,
Villen J.,
Beausoleil S.A.,
Bakalarski C.E.,
Elledge S.J.,
Gygi S.P.;
"A quantitative atlas of mitotic phosphorylation.";
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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[15]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[16]
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STRUCTURE BY NMR OF 4-118.
PubMed=9684899 [NCBI, ExPASy, EBI, Israel, Japan]
Fletcher C.M.,
Wagner G.;
"The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein.";
Protein Sci. 7:1639-1642(1998).
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[17]
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X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 36-70 IN COMPLEX WITH EIF4E AND MRNA CAP ANALOG.
DOI=10.1016/j.bbapap.2005.07.023; PubMed=16271312 [NCBI, ExPASy, EBI, Israel, Japan]
Tomoo K.,
Matsushita Y.,
Fujisaki H.,
Abiko F.,
Shen X.,
Taniguchi T.,
Miyagawa H.,
Kitamura K.,
Miura K.,
Ishida T.;
"Structural basis for mRNA cap-binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods.";
Biochim. Biophys. Acta 1753:191-208(2005).
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[18]
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X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 51-67 IN COMPLEX WITH EIF4E2 AND MRNA CAP ANALOG.
DOI=10.1016/j.jmb.2007.02.019; PubMed=17368478 [NCBI, ExPASy, EBI, Israel, Japan]
Rosettani P.,
Knapp S.,
Vismara M.G.,
Rusconi L.,
Cameron A.D.;
"Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.";
J. Mol. Biol. 368:691-705(2007).
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[19]
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X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 51-64 IN COMPLEX WITH EIF4E AND MRNA CAP ANALOG.
DOI=10.1016/j.jmb.2007.06.033; PubMed=17631896 [NCBI, ExPASy, EBI, Israel, Japan]
Brown C.J.,
McNae I.,
Fischer P.M.,
Walkinshaw M.D.;
"Crystallographic and mass spectrometric characterisation of eIF4E with N7-alkylated cap derivatives.";
J. Mol. Biol. 372:7-15(2007).
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