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UniProtKB/Swiss-Prot entry Q12045


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name VIK1_YEAST
Primary accession number Q12045
Secondary accession number Q7LGU6
Integrated into Swiss-Prot on January 9, 2007
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 41)
Name and origin of the protein
Protein name Spindle pole body-associated protein VIK1
Synonym Vegetative interaction with KAR3 protein 1
Gene name
Name: VIK1
OrderedLocusNames: YPL253C
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204511 / S288c / AB972;
PubMed=9169875 [NCBI, ExPASy, EBI, Israel, Japan]
Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
Nature 387:103-105(1997).
[2]
FUNCTION, INTERACTION WITH KAR3, AND SUBCELLULAR LOCATION.
DOI=10.1083/jcb.144.6.1219; PubMed=10087265 [NCBI, ExPASy, EBI, Israel, Japan]
Manning B.D., Barrett J.G., Wallace J.A., Granok H., Snyder M.;
"Differential regulation of the Kar3p kinesin-related protein by two associated proteins, Cik1p and Vik1p.";
J. Cell Biol. 144:1219-1233(1999).
[3]
FUNCTION, AND SUBCELLULAR LOCATION.
PubMed=11729143 [NCBI, ExPASy, EBI, Israel, Japan]
Shanks R.M.Q., Kamieniecki R.J., Dawson D.S.;
"The Kar3-interacting protein Cik1p plays a critical role in passage through meiosis I in Saccharomyces cerevisiae.";
Genetics 159:939-951(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z73609; CAA97978.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z67751; CAA91591.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z73608; CAA97977.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S61011; S61011.
RefSeq NP_015070.1; -.
3D structure databases
PDB
2O0A; X-ray; 1.60 A; A=353-647.[ExPASy / RCSB / EBI]
PDBsum 2O0A; -.
ModBase Q12045.
Protein-protein interaction databases
DIP DIP:2397N; -.
IntAct Q12045; -.
Organism-specific databases
CYGD YPL253c; -.
SGD S000006174; VIK1.
Yeast-GFP YPL253C.
Ontologies
GO
GO:0005871; Cellular component: kinesin complex (inferred from direct assay from SGD).
GO:0005634; Cellular component: nucleus (inferred from electronic annotation from UniProtKB-KW).
GO:0005816; Cellular component: spindle pole body (inferred from direct assay from SGD).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0007017; Biological process: microtubule-based process (inferred from mutant phenotype from SGD).
GO:0007064; Biological process: mitotic sister chromatid cohesion (inferred from genetic interaction from SGD).
QuickGo view.
Family and domain databases
ProtoNet Q12045.
Genome annotation databases
Ensembl YPL253C; Saccharomyces cerevisiae. [Contig view]
GeneID 855822; -.
GenomeReviews U00094_GR; YPL253C.
KEGG sce:YPL253C; -.
NMPDR fig|4932.3.peg.6196; -.
Phylogenomic databases
HOGENOM Q12045; -.
Other
LinkHub Q12045; -.
NextBio 980368; -.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Coiled coil; Complete proteome; Nucleus.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   647  647     Spindle pole body-associated protein VIK1. PRO_0000270929
COILED   202   350  149     Potential. 
HELIX   353   372  20      
STRAND   376   381  6      
HELIX   383   385  3      
STRAND   390   393  4      
TURN   394   397  4      
STRAND   398   401  4      
TURN   402   404  3      
STRAND   407   409  3      
STRAND   411   415  5      
TURN   416   418  3      
HELIX   421   427  7      
HELIX   430   438  9      
STRAND   443   448  6      
HELIX   454   465  12      
HELIX   470   474  5      
STRAND   475   485  11      
STRAND   490   492  3      
STRAND   506   509  4      
STRAND   514   518  5      
STRAND   521   525  5      
HELIX   526   529  4      
TURN   532   535  4      
STRAND   546   557  12      
STRAND   570   577  8      
HELIX   580   591  12      
HELIX   599   610  12      
STRAND   614   619  6      
HELIX   622   624  3      
HELIX   625   638  14      
Sequence information
Length: 647 AA [This is the length of the unprocessed precursor] Molecular weight: 75730 Da [This is the MW of the unprocessed precursor] CRC64: A6E61C51CC10B8EB [This is a checksum on the sequence]
        10         20         30         40         50         60 
MASQQNKHAF LSKNRIFHNP DNVSSSKSRN LMDITNTTNT MNGSRPSSMK SSLALPPVKD 

        70         80         90        100        110        120 
SFPSVSRSAS LNINMSKIKD LKDRQDKIRF QRHTLRTQLI ECEREIKTIK FRDLNKSRFE 

       130        140        150        160        170        180 
LYKKKSKQAK YLKQVRDLTQ NLNSKDGERA DLIKKNKSAL ATLQAELDQN LILKRQESQE 

       190        200        210        220        230        240 
LYNNKLIFWE NELQIMENVE PDHEITEEIS QLKKTLQELN INWANLQKQN LERQVNHESQ 

       250        260        270        280        290        300 
LRKDFIAFKE AKLKSMENLT NKHRELLDQI ATLQSESEKL HKEIMDIDRQ AEYSEQNISE 

       310        320        330        340        350        360 
INENIKQLEL ANNPLISKSL QNSQDLEHLQ NQMENLKEMA SKQEKFYNDT YNTVEKELLR 

       370        380        390        400        410        420 
SRRLENSIIE QKGTMRCYAY VMEQNLPENL LFDYENGVIT QGLSEHVYKF NRVIPHLKVS 

       430        440        450        460        470        480 
EDKFFTQEYS VYHDMCLNQK KNFNLISLST TPHGSLRESL IKFLAEKDTI YQKQYVITLQ 

       490        500        510        520        530        540 
FVFLSDDEFS QDMLLDYSHN DKDSIKLKFE KHSISLDSKL VIIENGLEDL PLNFSCDEHP 

       550        560        570        580        590        600 
NLPHSGMGII KVQFFPRDSK SDGNNDPVPV DFYFIELNNL KSIEQFDKSI FKKESCETPI 

       610        620        630        640 
ALVLKKLISD TKSFFLLNLN DSKNVNKLLT ISEEVQTQLC KRKKKLT 

Q12045 in FASTA format

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