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UniProtKB/Swiss-Prot entry Q0A6K5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DDL_ALHEH
Primary accession number Q0A6K5
Secondary accession numbers None
Integrated into Swiss-Prot on June 10, 2008
Sequence was last modified on October 17, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 23)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase
Synonyms EC 6.3.2.4
D-alanylalanine synthetase
D-Ala-D-Ala ligase
Gene name
Name: ddl
OrderedLocusNames: Mlg_2190
From
Alkalilimnicola ehrlichei (strain MLHE-1) [TaxID: 187272] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales; Ectothiorhodospiraceae; Alkalilimnicola.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Oremland R.S., Hoeft S.E., Switzer-Blum J., Kulp T., King G., Tabita R., Witte B., Santini J.M., Basu P., Hollibaugh J.T., Xie G., Stolz J.F., Richardson P.;
"Complete sequence of Alkalilimnicola ehrilichei MLHE-1.";
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000453; ABI57532.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_743022.1; -.
3D structure databases
ModBase Q0A6K5.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q0A6K5.
Genome annotation databases
GeneID 4270969; -.
GenomeReviews CP000453_GR; Mlg_2190.
KEGG aeh:Mlg_2190; -.
NMPDR fig|187272.6.peg.2087; -.
Phylogenomic databases
HOGENOM Q0A6K5; -.
Genome annotation databases
CMR Q0A6K5; Mlg_2190.
Other
ProtoNet Q0A6K5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   311  311     D-alanine--D-alanine ligase. PRO_0000341049
DOMAIN   106   301  196     ATP-grasp. 
NP_BIND   132   187  56     ATP (By similarity). 
METAL   255   255        Magnesium or manganese 1 (By similarity). 
METAL   268   268        Magnesium or manganese 1 (By similarity). 
METAL   268   268        Magnesium or manganese 2 (By similarity). 
METAL   270   270        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 311 AA [This is the length of the unprocessed precursor] Molecular weight: 33873 Da [This is the MW of the unprocessed precursor] CRC64: BCFD7FC34464A85B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSSEQAAAMG RVAVLMGGDS AEREISLISG RAVFEALRRR GVDAEAVDTA QVALAELTGF 

        70         80         90        100        110        120 
DRAFIALHGR GGEDGVIQGA LEALGVPYTG SGVLGCAIGM DKWRTKLLWR GAELPVPPGA 

       130        140        150        160        170        180 
LLRPETNRQA LIGSVGLPLM IKPAHEGSSI GMAKVERPEE LEAARAEAAR YDDLVLAERW 

       190        200        210        220        230        240 
IEGGEYTVAI LGEEALPAIR LETPRGFYDF EAKYRSGDTR YHCPAGLTEA EEQQIRQLAL 

       250        260        270        280        290        300 
DAFRVAGASG WGRVDFMRDR QGRFWLLEIN TIPGMTDHSL VPMAARAVGI DFDELCWRIL 

       310 
LDSRRREAGR P
Q0A6K5 in FASTA format

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