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UniProtKB/Swiss-Prot entry Q08513


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NTP1_SWPVK
Primary accession number Q08513
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1994
Sequence was last modified on October 1, 1994 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 32)
Name and origin of the protein
Protein name Nucleoside triphosphatase I [Fragment]
Synonyms EC 3.6.1.15
Nucleoside triphosphate phosphohydrolase I
NPH I
Gene name
Name: NPH1
From
Swinepox virus (strain Kasza) (SWPV) [TaxID: 10277] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Suipoxvirus.
Virus host Sus scrofa (Pig) [TaxID: 9823]
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1006/viro.1993.1625; PubMed=8249275 [NCBI, ExPASy, EBI, Israel, Japan]
Massung R.F., Jayarama V., Moyer R.W.;
"DNA sequence analysis of conserved and unique regions of swinepox virus: identification of genetic elements supporting phenotypic observations including a novel G protein-coupled receptor homologue.";
Virology 197:511-528(1993).
Comments
  • FUNCTION: Serves two roles in transcription; it acts in concert with viral termination factor/capping enzyme to catalyze release of UUUUUNU-containing nascent RNA from the elongation complex, and it acts by itself as a polymerase elongation factor to facilitate readthrough of intrinsic pause sites (By similarity).
  • CATALYTIC ACTIVITY: NTP + H2O = NDP + phosphate.
  • SIMILARITY: Belongs to the helicase family. NPH I subfamily.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L22012; AAA16175.1; -; Unassigned_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase Q08513.
Family and domain databases
InterPro IPR000330; SNF2_N.
Graphical view of domain structure.
Pfam PF00176; SNF2_N; 1.
Pfam graphical view of domain structure.
BLOCKS Q08513.
Other
ProtoNet Q08513.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Hydrolase; Nucleotide-binding; Transcription.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom  To Length Description FTId
CHAIN   1   >89  >89     Nucleoside triphosphatase I. PRO_0000099097
DOMAIN   42   >89  >48     Helicase ATP-binding. 
NP_BIND   55    62  8     ATP (By similarity). 
NON_TER   89    89         
Sequence information
Length: 89 AA [This is the length of the partial sequence of the unprocessed precursor] Molecular weight: 10240 Da [This is the MW of the partial sequence of the unprocessed precursor] CRC64: F550027F762EEDE6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSSYHAAYID YELRVTESMT DTMGTDTEIT LKPYQHFVAS VFLGLDKMHS LLLFHDTGVG 

        70         80 
KTITTTFIIK QLKNIYTNWS ILLLVKKHL 

Q08513 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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