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[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Adipocyte;
PubMed=7688729 [NCBI, ExPASy, EBI, Israel, Japan]
Abumrad N.A.,
El-Maghrabi M.R.,
Amri E.-Z.,
Lopez E.,
Grimaldi P.A.;
"Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36.";
J. Biol. Chem. 268:17665-17668(1993).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=Wistar;
PubMed=10409247 [NCBI, ExPASy, EBI, Israel, Japan]
Guthmann F.,
Haupt R.,
Looman A.C.,
Spener F.,
Ruestow B.;
"Fatty acid translocase/CD36 mediates the uptake of palmitate by type II pneumocytes.";
Am. J. Physiol. 277:L191-L196(1999).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=Dark agouti;
Zhang X.,
Mayrhofer G.,
Ey P.L.;
"Potential allele of rat CD36 antigen.";
Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
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[4]
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PROTEIN SEQUENCE OF 2-31, AND PALMITOYLATION AT CYS-3 AND CYS-7.
TISSUE=Adipocyte;
PubMed=7504047 [NCBI, ExPASy, EBI, Israel, Japan]
Jochen A.,
Hays J.;
"Purification of the major substrate for palmitoylation in rat adipocytes: N-terminal homology with CD36 and evidence for cell surface acylation.";
J. Lipid Res. 34:1783-1792(1993).
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[5]
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PROTEIN SEQUENCE OF 2-16.
STRAIN=Sprague-Dawley;
TISSUE=Adipocyte;
DOI=10.1007/BF00231876; PubMed=8320718 [NCBI, ExPASy, EBI, Israel, Japan]
Harmon C.M.,
Abumrad N.A.;
"Binding of sulfosuccinimidyl fatty acids to adipocyte membrane proteins: isolation and amino-terminal sequence of an 88-kD protein implicated in transport of long-chain fatty acids.";
J. Membr. Biol. 133:43-49(1993).
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- FUNCTION: Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
- TISSUE SPECIFICITY: Predominant in heart, intestine, spleen, fat, skeletal muscle, lower in testes.
- DEVELOPMENTAL STAGE: Induced during preadipocyte differentiation.
- SIMILARITY: Belongs to the CD36 family.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 472 AA [This is the length of the unprocessed precursor] |
Molecular weight: 52731 Da [This is the MW of the unprocessed precursor] |
CRC64: 69F9513B1B85CBF0 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MGCDRNCGLI TGAVIGAVLA VFGGILMPVG DLLIEKTIKR EVVLEEGTIA FKNWVKTGTT
70 80 90 100 110 120
VYRQFWIFDV QNPEEVAKNS SKIKVKQRGP YTYRVRYLAK ENITQDPKDS TVSFVQPNGA
130 140 150 160 170 180
IFEPSLSVGT ENDNFTVLNL AVAAAPHIYT NSFVQGVLNS LIKKSKSSMF QTRSLKELLW
190 200 210 220 230 240
GYKDPFLSLV PYPISTTVGV FYPYNNTVDG VYKVFNGKDN ISKVAIIDTY KGKRNLSYWE
250 260 270 280 290 300
SYCDMINGTD AASFPPFVEK SQTLRFFSSD ICRSIYAVFE SEVNLKGIPV YRFVLPANAF
310 320 330 340 350 360
ASPLQNPDNH CFCTEKVISN NCTSYGVLDI GKCKEGKPVY ISLPHFLHAS PDVSEPIEGL
370 380 390 400 410 420
NPNEDEHRTY LDVEPITGFT LQFAKRLQVN ILVKPARKIE ALKNLKRPYI VPILWLNETG
430 440 450 460 470
TIGDEKAEMF RNQVTGKIKL LGLVEMVLLG VGVVMFVAFM ISYCACRSKN GK
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Q07969 in FASTA format |
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