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UniProtKB/Swiss-Prot entry Q043Z5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ENO1_LACGA
Primary accession number Q043Z5
Secondary accession numbers None
Integrated into Swiss-Prot on March 20, 2007
Sequence was last modified on November 14, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 21)
Name and origin of the protein
Protein name Enolase 1
Synonyms EC 4.2.1.11
2-phosphoglycerate dehydratase 1
2-phospho-D-glycerate hydro-lyase 1
Gene name
Name: eno1
OrderedLocusNames: LGAS_0838
From
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) [TaxID: 324831] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0607117103; PubMed=17030793 [NCBI, ExPASy, EBI, Israel, Japan]
Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
"Comparative genomics of the lactic acid bacteria.";
Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000413; ABJ60227.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_814665.1; -.
3D structure databases
ModBase Q043Z5.
Ontologies
GO
GO:0009986; Cellular component: cell surface (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from HAMAP).
GO:0004634; Molecular function: phosphopyruvate hydratase activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00318; -; 1.
PBIL [Tree]
InterPro IPR000941; Enolase.
Graphical view of domain structure.
PANTHER PTHR11902; Enolase; 1.
Pfam PF00113; Enolase_C; 1.
PF03952; Enolase_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001400; Enolase; 1.
PRINTS PR00148; ENOLASE.
ProDom PD000902; Enolase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01060; eno; 1.
PROSITE PS00164; ENOLASE; 1.
BLOCKS Q043Z5.
Genome annotation databases
GeneID 4439983; -.
GenomeReviews CP000413_GR; LGAS_0838.
KEGG lga:LGAS_0838; -.
NMPDR fig|1596.1.peg.720; -.
Phylogenomic databases
HOGENOM Q043Z5; -.
Genome annotation databases
CMR Q043Z5; LGAS_0838.
Other
ProtoNet Q043Z5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; Lyase; Magnesium; Metal-binding; Secreted.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   428  428     Enolase 1. PRO_0000280855
REGION   365   368  4     Substrate binding (By similarity). 
ACT_SITE   205   205        Proton donor (By similarity). 
ACT_SITE   338   338        Proton acceptor (By similarity). 
METAL   242   242        Magnesium (By similarity). 
METAL   286   286        Magnesium (By similarity). 
METAL   313   313        Magnesium (By similarity). 
BINDING   155   155        Substrate (By similarity). 
BINDING   164   164        Substrate (By similarity). 
BINDING   286   286        Substrate (By similarity). 
BINDING   313   313        Substrate (By similarity). 
BINDING   338   338        Substrate (covalent); in inhibited form (By similarity). 
BINDING   389   389        Substrate (By similarity). 
Sequence information
Length: 428 AA [This is the length of the unprocessed precursor] Molecular weight: 46652 Da [This is the MW of the unprocessed precursor] CRC64: B276CE8CDFF5465A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLKSVIENVH ALEIFDSRGN PTVEVFVTLS NGVVGKAEVP SGASTGENEA VELRDGGSRL 

        70         80         90        100        110        120 
GGKGVMNAVN NVNTEINDAL KGLDPHDQPN IDATMIALDG TPNKGRLGAN AILGVSMATA 

       130        140        150        160        170        180 
CAAAKDNHQP LYRYLGGTDL EMPQTFHNVI NGGEHADNGI DIQEFMITPV AKTSFRDGFE 

       190        200        210        220        230        240 
KIVNVYHTLK KVLEDMGYET GLGDEGGFAP NMKNSEEALK ALHESIIKAG YKPGEDIAIA 

       250        260        270        280        290        300 
CDCAASYFYN KEDGKYHLEG KVLTDEELAD YYDKLLDEFP ELISMEDPYD ENDVEGMVKF 

       310        320        330        340        350        360 
TESHKDRIQI VLDDFICTNP KLLNKAIHEG AGNASLIKLN QIGTVTETLE TIRLSRKNGY 

       370        380        390        400        410        420 
NTMISHRSGE TGDTFIADFA VAVNGGQLKS GAPARSERVE KYNRLLEIEE ELGKGERLAF 


FPDNVDLD 

Q043Z5 in FASTA format

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