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UniProtKB/Swiss-Prot entry Q033G3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MTLD_LACLS
Primary accession number Q033G3
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on November 14, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 18)
Name and origin of the protein
Protein name Mannitol-1-phosphate 5-dehydrogenase
Synonym EC 1.1.1.17
Gene name
Name: mtlD
OrderedLocusNames: LACR_0030
From
Lactococcus lactis subsp. cremoris (strain SK11) [TaxID: 272622] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Lactococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0607117103; PubMed=17030793 [NCBI, ExPASy, EBI, Israel, Japan]
Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
"Comparative genomics of the lactic acid bacteria.";
Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000425; ABJ71659.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_808081.1; -.
3D structure databases
ModBase Q033G3.
Ontologies
GO
GO:0008926; Molecular function: mannitol-1-phosphate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00196; -; 1.
PBIL [Tree]
InterPro IPR013328; DHase_multihelical.
IPR013118; Mannitol_DHase_C.
IPR000669; Mannitol_DHase_core.
IPR013131; Mannitol_DHase_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF01232; Mannitol_dh; 1.
PF08125; Mannitol_dh_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00084; MTLDHDRGNASE.
PROSITE PS00974; MANNITOL_DHGENASE; 1.
BLOCKS Q033G3.
Genome annotation databases
GeneID 4433611; -.
GenomeReviews CP000425_GR; LACR_0030.
KEGG llc:LACR_0030; -.
CMR Q033G3; LACR_0030.
Other
ProtoNet Q033G3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   388  388     Mannitol-1-phosphate 5-dehydrogenase. PRO_1000011804
NP_BIND   4    15  12     NAD (By similarity). 
Sequence information
Length: 388 AA [This is the length of the unprocessed precursor] Molecular weight: 43993 Da [This is the MW of the unprocessed precursor] CRC64: 2ABC9359F30FB71D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKKAVHFGAG NIGRGFIGEI LSKNGFEIYF VDTNKAIIDE LNTRHSYEIG IASSSPEKIS 

        70         80         90        100        110        120 
VSGLFGINNG ENPEDVIEAI AQADIVTKAI GPNILPYIAE LVAKGIQKRK EENKQVQIDI 

       130        140        150        160        170        180 
IACENMIGGS EFLEKKVAEY LSDSDKVYLA NYIGFPNAAV DRIVPGQKHE DLLYVEVEPF 

       190        200        210        220        230        240 
CEWVIDESQI KNKSFKLEGV HYANNLEPFI ERKLFSVNSG HATVAYSSAY KGYKIILEGL 

       250        260        270        280        290        300 
QHKEILSALK GVQKETRALL LAKWPQYFTE EDLMSYHQMI ISRFANPKII DEVTRVARTP 

       310        320        330        340        350        360 
IRKLGYDERF IRPIRELNER GLSYQNHLDI VGKIFAYQDE NDSQSVQLQE KLSTMDLQRL 

       370        380 
IEEVTGLSNK KIILEIELVI KKYKNDSK 

Q033G3 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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