[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, CATALYTIC ACTIVITY, ENZYME REGULATION, DEVELOPMENTAL STAGE, AND KNOCKOUT.
DOI=10.1016/0092-8674(92)90411-5; PubMed=1348970 [NCBI, ExPASy, EBI, Israel, Japan]
Pitt G.S.,
Milona N.,
Borleis J.,
Lin K.C.,
Reed R.R.,
Devreotes P.N.;
"Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development.";
Cell 69:305-315(1992).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L.,
Pachebat J.A.,
Gloeckner G.,
Rajandream M.A.,
Sucgang R.,
Berriman M.,
Song J.,
Olsen R.,
Szafranski K.,
Xu Q.,
Tunggal B.,
Kummerfeld S.,
Madera M.,
Konfortov B.A.,
Rivero F.,
Bankier A.T.,
Lehmann R.,
Hamlin N.,
Davies R., ![]()
Gaudet P.,
Fey P.,
Pilcher K.,
Chen G.,
Saunders D.,
Sodergren E.J.,
Davis P.,
Kerhornou A.,
Nie X.,
Hall N.,
Anjard C.,
Hemphill L.,
Bason N.,
Farbrother P.,
Desany B.,
Just E.,
Morio T.,
Rost R.,
Churcher C.M.,
Cooper J.,
Haydock S.,
van Driessche N.,
Cronin A.,
Goodhead I.,
Muzny D.M.,
Mourier T.,
Pain A.,
Lu M.,
Harper D.,
Lindsay R.,
Hauser H.,
James K.D.,
Quiles M.,
Madan Babu M.,
Saito T.,
Buchrieser C.,
Wardroper A.,
Felder M.,
Thangavelu M.,
Johnson D.,
Knights A.,
Loulseged H.,
Mungall K.L.,
Oliver K.,
Price C.,
Quail M.A.,
Urushihara H.,
Hernandez J.,
Rabbinowitsch E.,
Steffen D.,
Sanders M.,
Ma J.,
Kohara Y.,
Sharp S.,
Simmonds M.N.,
Spiegler S.,
Tivey A.,
Sugano S.,
White B.,
Walker D.,
Woodward J.R.,
Winckler T.,
Tanaka Y.,
Shaulsky G.,
Schleicher M.,
Weinstock G.M.,
Rosenthal A.,
Cox E.C.,
Chisholm R.L.,
Gibbs R.A.,
Loomis W.F.,
Platzer M.,
Kay R.R.,
Williams J.G.,
Dear P.H.,
Noegel A.A.,
Barrell B.G.,
Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
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[3]
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FUNCTION, AND KNOCKOUT.
PubMed=8224844 [NCBI, ExPASy, EBI, Israel, Japan]
Pitt G.S.,
Brandt R.,
Lin K.C.,
Devreotes P.N.,
Schaap P.;
"Extracellular cAMP is sufficient to restore developmental gene expression and morphogenesis in Dictyostelium cells lacking the aggregation adenylyl cyclase (ACA).";
Genes Dev. 7:2172-2180(1993).
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[4]
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FUNCTION, CATALYTIC ACTIVITY, COFACTOR, ENZYME REGULATION, BIOPHYSICOCHEMICAL PROPERTIES, AND MUTAGENESIS OF LEU-394.
DOI=10.1074/jbc.271.31.18333; PubMed=8702473 [NCBI, ExPASy, EBI, Israel, Japan]
Parent C.A.,
Devreotes P.N.;
"Constitutively active adenylyl cyclase mutant requires neither G proteins nor cytosolic regulators.";
J. Biol. Chem. 271:18333-18336(1996).
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[5]
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FUNCTION, AND MUTAGENESIS OF PHE-306; SER-498; LYS-504; GLU-593 AND ILE-649.
DOI=10.1093/emboj/19.10.2247; PubMed=10811616 [NCBI, ExPASy, EBI, Israel, Japan]
Patel H.,
Guo K.,
Parent C.,
Gross J.,
Devreotes P.N.,
Weijer C.J.;
"A temperature-sensitive adenylyl cyclase mutant of Dictyostelium.";
EMBO J. 19:2247-2256(2000).
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[6]
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TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
DOI=10.1006/dbio.2001.0232; PubMed=11356026 [NCBI, ExPASy, EBI, Israel, Japan]
Verkerke-van Wijk I.,
Fukuzawa M.,
Devreotes P.N.,
Schaap P.;
"Adenylyl cyclase A expression is tip-specific in Dictyostelium slugs and directs StatA nuclear translocation and CudA gene expression.";
Dev. Biol. 234:151-160(2001).
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[7]
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TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
DOI=10.1046/j.1440-169x.2001.00572.x; PubMed=11422293 [NCBI, ExPASy, EBI, Israel, Japan]
Tsujioka M.,
Yokoyama M.,
Nishio K.,
Kuwayama H.,
Morio T.,
Katoh M.,
Urushihara H.,
Saito T.,
Ochiai H.,
Tanaka Y.,
Takeuchi I.,
Maeda M.;
"Spatial expression patterns of genes involved in cyclic AMP responses in Dictyostelium discoideum development.";
Dev. Growth Differ. 43:275-283(2001).
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[8]
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FUNCTION, SUBCELLULAR LOCATION, CONSTITUTIVELY ACTIVE MUTANT, AND KNOCKOUT.
DOI=10.1016/S0092-8674(03)00081-3; PubMed=12600317 [NCBI, ExPASy, EBI, Israel, Japan]
Kriebel P.W.,
Barr V.A.,
Parent C.A.;
"Adenylyl cyclase localization regulates streaming during chemotaxis.";
Cell 112:549-560(2003).
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[9]
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ENZYME REGULATION.
DOI=10.1016/j.cub.2005.01.007; PubMed=15668169 [NCBI, ExPASy, EBI, Israel, Japan]
Comer F.I.,
Lippincott C.K.,
Masbad J.J.,
Parent C.A.;
"The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxis.";
Curr. Biol. 15:134-139(2005).
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[10]
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FUNCTION, AND KNOCKOUT.
DOI=10.1128/EC.4.4.775-786.2005; PubMed=15821137 [NCBI, ExPASy, EBI, Israel, Japan]
Stepanovic V.,
Wessels D.,
Daniels K.,
Loomis W.F.,
Soll D.R.;
"Intracellular role of adenylyl cyclase in regulation of lateral pseudopod formation during Dictyostelium chemotaxis.";
Eukaryot. Cell 4:775-786(2005).
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[11]
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DEVELOPMENTAL STAGE.
DOI=10.1128/EC.5.4.658-664.2006; PubMed=16607013 [NCBI, ExPASy, EBI, Israel, Japan]
Siol O.,
Dingermann T.,
Winckler T.;
"The C-module DNA-binding factor mediates expression of the dictyostelium aggregation-specific adenylyl cyclase ACA.";
Eukaryot. Cell 5:658-664(2006).
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[12]
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ENZYME REGULATION.
DOI=10.1091/mbc.E05-08-0781; PubMed=16267269 [NCBI, ExPASy, EBI, Israel, Japan]
Comer F.I.,
Parent C.A.;
"Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase.";
Mol. Biol. Cell 17:357-366(2006).
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