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UniProtKB/Swiss-Prot entry Q01841

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TGM2_CHICK
Primary accession number Q01841
Secondary accession numbers None
Integrated into Swiss-Prot on April 1, 1993
Sequence was last modified on July 5, 2004 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 68)
Name and origin of the protein
Protein name Protein-glutamine gamma-glutamyltransferase 2
Synonyms EC 2.3.2.13
Tissue transglutaminase
TGase C
TGC
TG(C)
Transglutaminase-2
Gene name
Name: TGL2
From
Gallus gallus (Chicken) [TaxID: 9031] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 9-22; 181-191; 242-262; 383-401; 406-416; 430-448 AND 457-483.
TISSUE=Erythrocyte;
PubMed=1357669 [NCBI, ExPASy, EBI, Israel, Japan]
Weraarchakul-Boonmark N., Jeong J.M., Murthy S.N.P., Engel J.D., Lorand L.;
"Cloning and expression of chicken erythrocyte transglutaminase.";
Proc. Natl. Acad. Sci. U.S.A. 89:9804-9808(1992).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L02270; AAA49104.1; ALT_INIT; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A47203; A47203.
RefSeq NP_990779.1; -.
UniGene Gga.31956
3D structure databases
HSSP P21980; 1KV3. [HSSP ENTRY / PDB]
ModBase Q01841.
Family and domain databases
InterPro IPR008957; Fibronectin_typ-III-like_fold.
IPR013783; Ig-like_fold.
IPR008958; Transglutaminase_C.
IPR013808; Transglutaminase_CS.
IPR001102; Transglutaminase_N.
IPR002931; Trnsglumase_like.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.30; FN_III-like; 1.
G3DSA:2.60.40.10; Ig-like_fold; 1.
Pfam PF00927; Transglut_C; 2.
PF01841; Transglut_core; 1.
PF00868; Transglut_N; 1.
Pfam graphical view of domain structure.
SMART SM00460; TGc; 1.
SMART graphical view of domain structure.
PROSITE PS00547; TRANSGLUTAMINASES; 1.
BLOCKS Q01841.
Genome annotation databases
Ensembl ENSGALG00000006775; Gallus gallus. [Contig view]
GeneID 396432; -.
KEGG gga:396432; -.
Phylogenomic databases
HOGENOM Q01841; -.
HOVERGEN Q01841; -.
Other
ProtoNet Q01841.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acyltransferase; Calcium; Direct protein sequencing; Metal-binding; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   689  689     Protein-glutamine gamma-glutamyltransferase 2. PRO_0000213709
ACT_SITE   278   278        By similarity. 
ACT_SITE   336   336        By similarity. 
ACT_SITE   359   359        By similarity. 
METAL   399   399        Calcium (By similarity). 
METAL   401   401        Calcium (By similarity). 
METAL   447   447        Calcium (By similarity). 
METAL   452   452        Calcium (By similarity). 
Sequence information
Length: 689 AA [This is the length of the unprocessed precursor] Molecular weight: 77970 Da [This is the MW of the unprocessed precursor] CRC64: ACA3FA84B48A5AB3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAEELVLETC DLQCERNGRE HRTEEMGSQQ LVVRRGQPFT ITLNFAGRGY EEGVDKLAFD 

        70         80         90        100        110        120 
VETGPCPVET SGTRSHFTLT DCPEEGTWSA VLQQQDGATL CVSLCSPSIA RVGRYRLTLE 

       130        140        150        160        170        180 
ASTGYQGSSF HLGDFVLLFN AWHPEDAVYL KEEDERREYV LSQQGLIYMG SRDYITSTPW 

       190        200        210        220        230        240 
NFGQFEDEIL AICLEMLDIN PKFLRDQNLD CSRRNDPVYI GRVVSAMVNC NDEDHGVLLG 

       250        260        270        280        290        300 
RWDNHYEDGM SPMAWIGSVD ILKRWRRLGC QPVKYGQCWV FAAVACTVMR CLGVPSRVVT 

       310        320        330        340        350        360 
NYNSAHDTNG NLVIDRYLSE TGMEERRSTD MIWNFHCWVE CWMTRPDLAP GYDGWQALDP 

       370        380        390        400        410        420 
TPQEKSEGVY CCGPAPVKAI KEGDLQVQYD IPFVFAEVNA DVVYWIVQSD GEKKKSTHSS 

       430        440        450        460        470        480 
VVGKNISTKS VGRDSREDIT HTYKYPEGSE KEREVFSKAE HEKSSLGEQE EGLHMRIKLS 

       490        500        510        520        530        540 
EGANNGSDFD VFAFISNDTD KERECRLRLC ARTASYNGEV GPQCGFKDLL NLSLQPHMEQ 

       550        560        570        580        590        600 
SVPLRILYEQ YGPNLTQDNM IKVVALLTEY ETGDSVVAIR DVYIQNPEIK IRILGEPMQE 

       610        620        630        640        650        660 
RKLVAEIRLV NPLAEPLNNC IFVVEGAGLT EGQRIEELED PVEPQAEAKF RMEFVPRQAG 

       670        680 
LHKLMVDFES DKLTGVKGYR NVIIAPLPK
Q01841 in FASTA format

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