ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P96789

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name 6PGD_LACLM
Primary accession number P96789
Secondary accession number A2RIU0
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on May 1, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 58)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
OrderedLocusNames: llmg_0586
From
Lactococcus lactis subsp. cremoris (strain MG1363) [TaxID: 416870] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Lactococcus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1042/0264-6021:3380055; PubMed=9931298 [NCBI, ExPASy, EBI, Israel, Japan]
Tetaud E., Hanau S., Wells J.M., Le Page R.W.F., Adams M.J., Arkison S., Barrett M.P.;
"6-phosphogluconate dehydrogenase from Lactococcus lactis: a role for arginine residues in binding substrate and coenzyme.";
Biochem. J. 338:55-60(1999).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01768-06; PubMed=17307855 [NCBI, ExPASy, EBI, Israel, Japan]
Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.;
"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363.";
J. Bacteriol. 189:3256-3270(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U74322; AAC12804.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AM406671; CAL97186.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001031931.1; -.
3D structure databases
PDB
2IYO; X-ray; 2.40 A; A=1-472.[ExPASy / RCSB / EBI]
2IYP; X-ray; 2.79 A; A/B/C=1-472.[ExPASy / RCSB / EBI]
2IZ0; X-ray; 2.60 A; A/B/C=1-472.[ExPASy / RCSB / EBI]
2IZ1; X-ray; 2.30 A; A/B/C=1-472.[ExPASy / RCSB / EBI]
Detailed list of linked structures.
PDBsum 2IYO; -.
2IYP; -.
2IZ0; -.
2IZ1; -.
ModBase P96789.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS P96789.
Genome annotation databases
GeneID 4798708; -.
GenomeReviews AM406671_GR; llmg_0586.
KEGG llm:llmg_0586; -.
CMR P96789; llmg_0586.
Other
ProtoNet P96789.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   472  472     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090046
CONFLICT   43    43        Y -> F (in Ref. 1; AAC12804). 
STRAND   4     9  6      
HELIX   13    23  11      
TURN   24    26  3      
STRAND   29    32  4      
HELIX   36    45  10      
TURN   46    48  3      
STRAND   51    53  3      
HELIX   57    62  6      
STRAND   69    72  4      
HELIX   78    87  10      
HELIX   88    90  3      
STRAND   96    99  4      
HELIX   105   117  13      
STRAND   121   129  9      
HELIX   130   136  7      
STRAND   139   144  6      
HELIX   146   159  14      
TURN   164   166  3      
STRAND   169   171  3      
HELIX   179   207  29      
HELIX   213   223  11      
TURN   224   228  5      
HELIX   231   239  9      
STRAND   247   250  4      
HELIX   251   253  3      
HELIX   264   275  12      
HELIX   280   293  14      
HELIX   295   302  8      
HELIX   316   348  33      
HELIX   355   361  7      
STRAND   363   366  4      
HELIX   373   382  10      
HELIX   389   391  3      
HELIX   393   416  24      
HELIX   421   433  13      
HELIX   440   451  12      
STRAND   455   464  10      
Sequence information
Length: 472 AA [This is the length of the unprocessed precursor] Molecular weight: 52460 Da [This is the MW of the unprocessed precursor] CRC64: A0075C9F46171F1C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAQANFGVVG MAVMGKNLAL NVESRGYTVA IYNRTTSKTE EVYKEHQDKN LVFTKTLEEF 

        70         80         90        100        110        120 
VGSLEKPRRI MLMVQAGAAT DATIKSLLPL LDIGDILIDG GNTHFPDTMR RNAELADSGI 

       130        140        150        160        170        180 
NFIGTGVSGG EKGALLGPSM MPGGQKEAYD LVAPIFEQIA AKAPQDGKPC VAYMGANGAG 

       190        200        210        220        230        240 
HYVKMVHNGI EYGDMQLIAE SYDLLKRILG LSNAEIQAIF EEWNEGELDS YLIEITKEVL 

       250        260        270        280        290        300 
KRKDDEGEGY IVDKILDKAG NKGTGKWTSE SALDLGVPLP LITESVFARY ISTYKDERVK 

       310        320        330        340        350        360 
ASKVLSGPAL DFSGDKKEVI EKIRKALYFS KIMSYAQGFA QLRKASEEFD WDLPYGTIAQ 

       370        380        390        400        410        420 
IWRAGCIIRA EFLQNITDAF DKDSELENLL LDDYFVDITK RYQEAVRDVV SLAVQAGTPI 

       430        440        450        460        470 
PTFTSAISYY DSYRSENLPA NLIQAQRDYF GAHTYERTDK AGIFHYDWYT ED
P96789 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!