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UniProtKB/Swiss-Prot entry P95999


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GGPS_SULSO
Primary accession number P95999
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on June 20, 2001 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 57)
Name and origin of the protein
Protein name Geranylgeranyl pyrophosphate synthetase
Synonyms GGPP synthetase
GGPS
Includes Dimethylallyltranstransferase
     (EC 2.5.1.1)
Geranyltranstransferase
     (EC 2.5.1.10)
Farnesyltranstransferase
     (EC 2.5.1.29)
Gene name
Name: gds
Synonyms: gds-1
OrderedLocusNames: SSO0061
ORFNames: C05010, C05_049
From
Sulfolobus solfataricus [TaxID: 2287] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
PubMed=8899719 [NCBI, ExPASy, EBI, Israel, Japan]
Sensen C.W., Klenk H.-P., Singh R.K., Allard G., Chan C.C.-Y., Liu Q.Y., Penny S.L., Young F., Schenk M.E., Gaasterland T., Doolittle W.F., Ragan M.A., Charlebois R.L.;
"Organizational characteristics and information content of an archaeal genome: 156 kb of sequence from Sulfolobus solfataricus P2.";
Mol. Microbiol. 22:175-191(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
DOI=10.1073/pnas.141222098; PubMed=11427726 [NCBI, ExPASy, EBI, Israel, Japan]
She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
"The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Y08257; CAA69541.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE006647; AAK40423.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR H90145; H90145.
S75427; S75427.
RefSeq NP_341633.1; -.
3D structure databases
ModBase P95999.
Enzyme and pathway databases
BioCyc SSOL273057:SSO0061-MON; -.
Family and domain databases
InterPro IPR002197; HTH_Fis.
IPR000092; Polyprenyl_synt.
IPR017446; Polyprenyl_synth-rel.
IPR008949; Terpenoid_synth.
Graphical view of domain structure.
Gene3D G3DSA:1.10.600.10; Terpenoid_synth; 1.
PANTHER PTHR12001; Polyprenyl_synt; 1.
Pfam PF00348; polyprenyl_synt; 1.
Pfam graphical view of domain structure.
PRINTS PR01590; HTHFIS.
PROSITE PS00723; POLYPRENYL_SYNTHET_1; 1.
PS00444; POLYPRENYL_SYNTHET_2; 1.
BLOCKS P95999.
Genome annotation databases
GeneID 1455314; -.
GenomeReviews AE006641_GR; SSO0061.
KEGG sso:SSO0061; -.
NMPDR fig|273057.1.peg.56; -.
Phylogenomic databases
HOGENOM P95999; -.
Genome annotation databases
CMR P95999; SSO0061.
Other
ProtoNet P95999.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Isoprene biosynthesis; Lipid synthesis; Multifunctional enzyme; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   332  332     Geranylgeranyl pyrophosphate synthetase. PRO_0000123974
CONFLICT   122   122        A -> S (in Ref. 1; CAA69541). 
CONFLICT   126   126        A -> S (in Ref. 1; CAA69541). 
Sequence information
Length: 332 AA [This is the length of the unprocessed precursor] Molecular weight: 37228 Da [This is the MW of the unprocessed precursor] CRC64: 2E3BEC59432CBD41 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSSDDLSLYF NEIVNNVNFR IKNFVKSNFK TLEEASFHLF TAGGKRLRPL VLVSSSDLIG 

        70         80         90        100        110        120 
GDRERAYKAA AAVEILHNFT LVHDDIMDND GLRRGLPTVH VKWGEPMAIL AGDYLHAKAF 

       130        140        150        160        170        180 
EALNEALKGL DGNTFYKAFS IFITSIEIIS EGQAMDMSFE NRLDVTEEEY IQMIKGKTAM 

       190        200        210        220        230        240 
LFSCSAALGG IINKANDDVV KKLTEYGLNL GISFQIVDDI LGIIGDEKEL GKPIYSDIRE 

       250        260        270        280        290        300 
GKKTILVIKT LSEATEDEKK ILVSTLGNKE AKKEDLERAS EIIRKHSLQY AYDLAKKYSD 

       310        320        330 
LAIENLREIP VSNKTAEKAL KYLAQFTIQR RK 

P95999 in FASTA format

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