ID   CHLY_CARPA              Reviewed;          25 AA.
AC   P81241;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 1.
DT   02-SEP-2008, entry version 39.
DE   RecName: Full=Bifunctional chitinase/lysozyme;
DE   Includes:
DE     RecName: Full=Chitinase;
DE              EC=3.2.1.14;
DE   Includes:
DE     RecName: Full=Lysozyme;
DE              EC=3.2.1.17;
DE   Flags: Fragments;
OS   Carica papaya (Papaya).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids II; Brassicales; Caricaceae; Carica.
OX   NCBI_TaxID=3649;
RN   [1]
RP   PROTEIN SEQUENCE OF 1-22.
RC   TISSUE=Latex;
RX   MEDLINE=20063791; PubMed=10594185; DOI=10.1007/PL00000075;
RA   Subroto T., Sufiati S., Beintema J.J.;
RT   "Papaya (Carica papaya) lysozyme is a member of the family 19 (basic,
RT   class II) chitinases.";
RL   J. Mol. Evol. 49:819-821(1999).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-5 AND 23-25.
RC   TISSUE=Latex;
RX   MEDLINE=69130229; PubMed=5773045;
RA   Howard J.B., Glazer A.N.;
RT   "Papaya lysozyme. Terminal sequences and enzymatic properties.";
RL   J. Biol. Chem. 244:1399-1409(1969).
CC   -!- FUNCTION: Bifunctional enzyme with lysozyme/chitinase activity.
CC   -!- CATALYTIC ACTIVITY: Random hydrolysis of N-acetyl-beta-D-
CC       glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of 1,4-beta-linkages between N-
CC       acetylmuramic acid and N-acetyl-D-glucosamine residues in a
CC       peptidoglycan and between N-acetyl-D-glucosamine residues in
CC       chitodextrins.
CC   -!- SUBUNIT: Monomer.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 19 family. Chitinase
CC       class I subfamily.
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DR   InterPro; IPR000726; Glyco_hydro_19_cat.
DR   Pfam; PF00182; Glyco_hydro_19; 1.
DR   PROSITE; PS00773; CHITINASE_19_1; PARTIAL.
DR   PROSITE; PS00774; CHITINASE_19_2; PARTIAL.
PE   1: Evidence at protein level;
KW   Carbohydrate metabolism; Chitin degradation;
KW   Direct protein sequencing; Glycosidase; Hydrolase;
KW   Multifunctional enzyme; Polysaccharide degradation; Secreted.
FT   CHAIN         1    >25       Bifunctional chitinase/lysozyme.
FT                                /FTId=PRO_0000124810.
FT   CONFLICT      3      3       E -> S (in Ref. 2; AA sequence).
FT   NON_CONS     22     23
FT   NON_TER      25     25
SQ   SEQUENCE   25 AA;  2877 MW;  33BA3F018F33ACD6 CRC64;
     GIEKIISRSM FDQMLKHRNN PASFG
//