ID AMP1_CHICK Reviewed; 39 AA. AC P80389; DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot. DT 01-NOV-1995, sequence version 1. DT 22-JUL-2008, entry version 25. DE RecName: Full=Antimicrobial peptide CHP1; DE AltName: Full=Chicken heterophil peptide 1; OS Gallus gallus (Chicken). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; OC Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. OX NCBI_TaxID=9031; RN [1] RP PROTEIN SEQUENCE. RX MEDLINE=95053386; PubMed=7964174; RA Evans E.W., Beach G.G., Wunderlich J., Harmon B.G.; RT "Isolation of antimicrobial peptides from avian heterophils."; RL J. Leukoc. Biol. 56:661-665(1994). CC -!- FUNCTION: Bactericidal activity; inhibits Staphylococcus aureus CC and Escherichia coli. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSGALG00000022815; Gallus gallus. DR HOVERGEN; P80389; -. DR InterPro; IPR001855; Defensin_beta. DR Pfam; PF00711; Defensin_beta; 1. PE 1: Evidence at protein level; KW Antibiotic; Antimicrobial; Direct protein sequencing. FT PEPTIDE 1 39 Antimicrobial peptide CHP1. FT /FTId=PRO_0000044771. FT DISULFID 6 28 By similarity. FT DISULFID 13 34 By similarity. FT DISULFID 18 35 By similarity. SQ SEQUENCE 39 AA; 4480 MW; 5DDF1051693D254E CRC64; GRKSDCFRKS GFCAFLKCPS LTLISGKCSR FYLCCKRIR //