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UniProtKB/Swiss-Prot entry P77467


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PAAG_ECOLI
Primary accession number P77467
Secondary accession number O53015
Integrated into Swiss-Prot on July 15, 1998
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    June 10, 2008 (Entry version 60)
Name and origin of the protein
Protein name Probable enoyl-CoA hydratase paaG
Synonym EC 4.2.1.17
Gene name
Name: paaG
Synonyms: ydbT
OrderedLocusNames: b1394, JW1389
From
Escherichia coli (strain K12) [TaxID: 83333] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=W / ATCC 11105 / DSM 1900;
DOI=10.1074/jbc.273.40.25974; PubMed=9748275 [NCBI, ExPASy, EBI, Israel, Japan]
Ferrandez A., Minambres B., Garcia B., Olivera E.R., Luengo J.M., Garcia J.L., Diaz E.;
"Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway.";
J. Biol. Chem. 273:25974-25986(1998).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1093/dnares/3.6.363; PubMed=9097039 [NCBI, ExPASy, EBI, Israel, Japan]
Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T.;
"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.";
DNA Res. 3:363-377(1996).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
DOI=10.1126/science.277.5331.1453; PubMed=9278503 [NCBI, ExPASy, EBI, Israel, Japan]
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.;
"The complete genome sequence of Escherichia coli K-12.";
Science 277:1453-1474(1997).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1038/msb4100049; PubMed=16738553 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.";
Mol. Syst. Biol. 2:E1-E5(2006).
[5]
TRANSCRIPTIONAL REGULATION.
DOI=10.1074/jbc.275.16.12214; PubMed=10766858 [NCBI, ExPASy, EBI, Israel, Japan]
Ferrandez A., Garcia J.L., Diaz E.;
"Transcriptional regulation of the divergent paa catabolic operons for phenylacetic acid degradation in Escherichia coli.";
J. Biol. Chem. 275:12214-12222(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X97452; CAA66096.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U00096; AAC74476.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AP009048; BAA15000.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR E64890; E64890.
RefSeq AP_002021.1; -.
NP_415912.1; -.
3D structure databases
HSSP P14604; 1MJ3. [HSSP ENTRY / PDB]
ModBase P77467.
Protein-protein interaction databases
IntAct P77467; -.
Enzyme and pathway databases
BioCyc EcoCyc:G6715-MON; -.
Organism-specific databases
EchoBASE EB3504; -.
EcoGene EG13741; paaG.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR001753; Crotonase_core.
IPR011968; PaaB1.
Graphical view of domain structure.
Pfam PF00378; ECH; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR02280; PaaB1; 1.
PROSITE PS00166; ENOYL_COA_HYDRATASE; FALSE_NEG.
BLOCKS P77467.
Genome annotation databases
GeneID 946263; -.
GenomeReviews U00096_GR; b1394.
AP009048_GR; JW1389.
KEGG ecj:JW1389; -.
eco:b1394; -.
Phylogenomic databases
HOGENOM P77467; -.
Genome annotation databases
CMR P77467; b1394.
Other
ProtoNet P77467.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Fatty acid metabolism; Lipid metabolism; Lyase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   262  262     Probable enoyl-CoA hydratase paaG. PRO_0000109331
VARIANT   121   121  1     G -> C (in strain: W). 
Sequence information
Length: 262 AA [This is the length of the unprocessed precursor] Molecular weight: 28405 Da [This is the MW of the unprocessed precursor] CRC64: DD7B95B30D88660C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MMEFILSHVE KGVMTLTLNR PERLNSFNDE MHAQLAECLK QVERDDTIRC LLLTGAGRGF 

        70         80         90        100        110        120 
CAGQDLNDRN VDPTGPAPDL GMSVERFYNP LVRRLAKLPK PVICAVNGVA AGAGATLALG 

       130        140        150        160        170        180 
GDIVIAARSA KFVMAFSKLG LIPDCGGTWL LPRVAGRARA MGLALLGNQL SAEQAHEWGM 

       190        200        210        220        230        240 
IWQVVDDETL ADTAQQLARH LATQPTFGLG LIKQAINSAE TNTLDTQLDL ERDYQRLAGR 

       250        260 
SADYREGVSA FLAKRSPQFT GK 

P77467 in FASTA format

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