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UniProtKB/Swiss-Prot entry P72946

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HISX2_SYNY3
Primary accession number P72946
Secondary accession numbers None
Integrated into Swiss-Prot on March 25, 2003
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 49)
Name and origin of the protein
Protein name Putative histidinol dehydrogenase 2
Synonyms HDH 2
EC 1.1.1.23
Gene name
Name: hisD2
OrderedLocusNames: slr0682
From
Synechocystis sp. (strain PCC 6803) [TaxID: 1148] [HAMAP proteome]
Taxonomy Bacteria; Cyanobacteria; Chroococcales; Synechocystis.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/dnares/3.3.109; PubMed=8905231 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.";
DNA Res. 3:109-136(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000022; BAA16963.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S74923; S74923.
RefSeq NP_440283.1; -.
3D structure databases
ModBase P72946.
Enzyme and pathway databases
BioCyc SSP1148:SLR0682-MON; -.
Ontologies
GO
GO:0004399; Molecular function: histidinol dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from InterPro).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01024; atypical; 1.
PBIL [Tree]
InterPro IPR001692; Histidinol_DHase.
IPR012131; Hstdl_DHase_prok.
Graphical view of domain structure.
PANTHER PTHR21256:SF2; Hstdl_DH_prok; 1.
Pfam PF00815; Histidinol_dh; 1.
Pfam graphical view of domain structure.
PRINTS PR00083; HOLDHDRGNASE.
ProDom PD002680; Histidinol_dh; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00611; HISOL_DEHYDROGENASE; FALSE_NEG.
ProtoNet P72946.
Genome annotation databases
GeneID 953582; -.
GenomeReviews BA000022_GR; slr0682.
KEGG syn:slr0682; -.
NMPDR fig|1148.1.peg.384; -.
Phylogenomic databases
HOGENOM P72946; -.
Genome annotation databases
CMR P72946; slr0682.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   409  409     Putative histidinol dehydrogenase 2. PRO_0000135866
Sequence information
Length: 409 AA [This is the length of the unprocessed precursor] Molecular weight: 45138 Da [This is the MW of the unprocessed precursor] CRC64: 2EC7B208A7C67073 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLRLITQSGD IVQELRRLHH RPVPSPWPVM AQVVAAMEHW AAMDQDAPPR VSGAELDAAY 

        70         80         90        100        110        120 
QRISQEKLSV IRQACAALEQ VYRPQLPKTQ VSFPEDGTVR GQRFYPVRRA GFYLEAKRGD 

       130        140        150        160        170        180 
ALGNLLRQGM LAKTVGVAER VLVTETISST ILVAAQEMGI EEIYLAAGVP AIAMLTWGAK 

       190        200        210        220        230        240 
NIAPVESITG AGCPRVMAAK QLVSGVVTID QTLARTNLMV LADGEANGQW LALDLLAHAE 

       250        260        270        280        290        300 
QYPNASAVLL TDRLELGEEV IQSVNRYCRE QEHSVHTEKA LAHYGLVAIV EDLEACGSWI 

       310        320        330        340        350        360 
NEFCPHILLL AMEDPWTMVE KVQRAREIYI GHRSPSILGH YLSGANRLQT QDGAMATASE 

       370        380        390        400 
LAFHCFLRSS QLLDYGNNPP PPWLKDLVNW QGLTAIEERL GQLGRLKES
P72946 in FASTA format

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