NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/dnares/3.3.109; PubMed=8905231 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.";
DNA Res. 3:109-136(1996).

Comments

FUNCTION: This small ubiquitous enzyme is essential for maintenance and cell growth.
CATALYTIC ACTIVITY: ATP + AMP = 2 ADP.
SUBUNIT: Monomer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the adenylate kinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000022; BAA16643.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S74491; S74491.

RefSeq

NP_439963.1; -.

3D structure databases

HSSP

P27142; 1ZIN. [HSSP ENTRY / PDB]

ModBase

P72641.

Enzyme and pathway databases

BioCyc

SSP1148:SLL1059-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004017;	Molecular function: adenylate kinase activity (inferred from electronic annotation from HAMAP).
GO:0005524;	Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0009165;	Biological process: nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00235; -; 1.
PBIL [Tree]

InterPro

IPR000850; Adenylate_kin.
Graphical view of domain structure.

PANTHER

PTHR23359; Adenylate_kin; 1.

Pfam

PF00406; ADK; 1.
Pfam graphical view of domain structure.

PRINTS

PR00094; ADENYLTKNASE.

ProDom

PD000657; Adenylate_kin; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00113; ADENYLATE_KINASE; FALSE_NEG.

ProtoNet

P72641.

Genome annotation databases

GeneID

952893; -.

GenomeReviews

BA000022_GR; sll1059.

KEGG

syn:sll1059; -.

NMPDR

fig|1148.1.peg.64; -.

Phylogenomic databases

HOGENOM

P72641; -.

Genome annotation databases

CMR

P72641; sll1059.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 181`	`181`	`Probable adenylate kinase 2.`	`PRO_0000158872`
`NP_BIND`	`7 15`	`9`	`ATP (By similarity).`

Sequence information

Length: 181 AA [This is the length of the unprocessed precursor]

Molecular weight: 20340 Da [This is the MW of the unprocessed precursor]

CRC64: 3935871CA87958EE [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRLVMLGGPG SGKSTQSHNL SQELKLPVIS MGGILREAIA NATPLGIKAK PYVERGDLLP 

        70         80         90        100        110        120 
DPMMIEFIQQ RLVQEDGGQG WILEGYPRTA FQAEELDFLL EDLGQPLDWA LYLKIDEATM 

       130        140        150        160        170        180 
VERSLNRSLF DDHPEAITTR IGKFHEYTVP LLEYYAAKQN LLTVNAYPEV DQVTKLILAR 


L

P72641 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools