[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=85P;
PubMed=2001995 [NCBI, ExPASy, EBI, Israel, Japan]
Labigne A.,
Cussac V.,
Courcoux P.;
"Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity.";
J. Bacteriol. 173:1920-1931(1991).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=CPM630;
DOI=10.1093/nar/18.2.362; PubMed=2326167 [NCBI, ExPASy, EBI, Israel, Japan]
Clayton C.L.,
Pallen M.J.,
Kleanthous H.,
Wren B.W.,
Tabaqchali S.;
"Nucleotide sequence of two genes from Helicobacter pylori encoding for urease subunits.";
Nucleic Acids Res. 18:362-362(1990).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700392 / 26695;
DOI=10.1038/41483; PubMed=9252185 [NCBI, ExPASy, EBI, Israel, Japan]
Tomb J.-F.,
White O.,
Kerlavage A.R.,
Clayton R.A.,
Sutton G.G.,
Fleischmann R.D.,
Ketchum K.A.,
Klenk H.-P.,
Gill S.R.,
Dougherty B.A.,
Nelson K.E.,
Quackenbush J.,
Zhou L.,
Kirkness E.F.,
Peterson S.N.,
Loftus B.J.,
Richardson D.L.,
Dodson R.J.,
Khalak H.G., ![]()
Glodek A.,
McKenney K.,
FitzGerald L.M.,
Lee N.,
Adams M.D.,
Hickey E.K.,
Berg D.E.,
Gocayne J.D.,
Utterback T.R.,
Peterson J.D.,
Kelley J.M.,
Cotton M.D.,
Weidman J.F.,
Fujii C.,
Bowman C.,
Watthey L.,
Wallin E.,
Hayes W.S.,
Borodovsky M.,
Karp P.D.,
Smith H.O.,
Fraser C.M.,
Venter J.C.;
"The complete genome sequence of the gastric pathogen Helicobacter pylori.";
Nature 388:539-547(1997).
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[4]
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PROTEIN SEQUENCE OF 1-30, CATALYTIC ACTIVITY, AND KINETIC PARAMETERS.
DOI=10.1016/0882-4010(91)90062-F; PubMed=1857197 [NCBI, ExPASy, EBI, Israel, Japan]
Evans D.J. Jr.,
Evans D.G.,
Kirkpatrick S.S.,
Graham D.Y.;
"Characterization of the Helicobacter pylori urease and purification of its subunits.";
Microb. Pathog. 10:15-26(1991).
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[5]
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PROTEIN SEQUENCE OF 1-20, CATALYTIC ACTIVITY, KINETIC PARAMETERS, AND INTERACTION WITH UREA.
PubMed=2188975 [NCBI, ExPASy, EBI, Israel, Japan]
Dunn B.E.,
Campbell G.P.,
Perez-Perez G.I.,
Blaser M.J.;
"Purification and characterization of urease from Helicobacter pylori.";
J. Biol. Chem. 265:9464-9469(1990).
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[6]
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PROTEIN SEQUENCE OF 1-15.
PubMed=2318539 [NCBI, ExPASy, EBI, Israel, Japan]
Hu L.-T.,
Mobley H.L.T.;
"Purification and N-terminal analysis of urease from Helicobacter pylori.";
Infect. Immun. 58:992-998(1990).
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[7]
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PROTEIN SEQUENCE OF 1-12.
STRAIN=ATCC 43504 / NCTC 11637 / JCM 7653 / RPH 13487;
PubMed=1452359 [NCBI, ExPASy, EBI, Israel, Japan]
Turbett G.R.,
Hoej P.B.,
Horne R.,
Mee B.J.;
"Purification and characterization of the urease enzymes of Helicobacter species from humans and animals.";
Infect. Immun. 60:5259-5266(1992).
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[8]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 565-569, AND KNOCKOUT.
STRAIN=85P;
PubMed=1313413 [NCBI, ExPASy, EBI, Israel, Japan]
Cussac V.,
Ferrero R.L.,
Labigne A.;
"Expression of Helicobacter pylori urease genes in Escherichia coli grown under nitrogen-limiting conditions.";
J. Bacteriol. 174:2466-2473(1992).
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[9]
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CATALYTIC ACTIVITY.
PubMed=1612735 [NCBI, ExPASy, EBI, Israel, Japan]
Hu L.-T.,
Foxall P.A.,
Russell R.,
Mobley H.L.T.;
"Purification of recombinant Helicobacter pylori urease apoenzyme encoded by ureA and ureB.";
Infect. Immun. 60:2657-2666(1992).
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[10]
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FUNCTION, AND ROLE IN VIRULENCE.
PubMed=8039935 [NCBI, ExPASy, EBI, Israel, Japan]
Tsuda M.,
Karita M.,
Morshed M.G.,
Okita K.,
Nakazawa T.;
"A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach.";
Infect. Immun. 62:3586-3589(1994).
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[11]
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SUBCELLULAR LOCATION.
PubMed=8641799 [NCBI, ExPASy, EBI, Israel, Japan]
Phadnis S.H.,
Parlow M.H.,
Levy M.,
Ilver D.,
Caulkins C.M.,
Connors J.B.,
Dunn B.E.;
"Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis.";
Infect. Immun. 64:905-912(1996).
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[12]
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INDUCTION.
DOI=10.1128/IAI.69.8.4891-4897.2001; PubMed=11447165 [NCBI, ExPASy, EBI, Israel, Japan]
van Vliet A.H.M.,
Kuipers E.J.,
Waidner B.,
Davies B.J.,
de Vries N.,
Penn C.W.,
Vandenbroucke-Grauls C.M.J.E.,
Kist M.,
Bereswill S.,
Kusters J.G.;
"Nickel-responsive induction of urease expression in Helicobacter pylori is mediated at the transcriptional level.";
Infect. Immun. 69:4891-4897(2001).
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[13]
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INDUCTION.
DOI=10.1099/mic.0.28188-0; PubMed=16339943 [NCBI, ExPASy, EBI, Israel, Japan]
Belzer C.,
Stoof J.,
Beckwith C.S.,
Kuipers E.J.,
Kusters J.G.,
van Vliet A.H.M.;
"Differential regulation of urease activity in Helicobacter hepaticus and Helicobacter pylori.";
Microbiology 151:3989-3995(2005).
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[14]
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X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) IN COMPLEX WITH NICKEL IONS, SUBUNIT STRUCTURE, AND CARBAMYLATION AT LYS-219.
DOI=10.1038/88563; PubMed=11373617 [NCBI, ExPASy, EBI, Israel, Japan]
Ha N.-C.,
Oh S.-T.,
Sung J.Y.,
Cha K.A.,
Lee M.H.,
Oh B.-H.;
"Supramolecular assembly and acid resistance of Helicobacter pylori urease.";
Nat. Struct. Biol. 8:505-509(2001).
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