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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
DOI=10.1038/35054089; PubMed=11206551 [NCBI, ExPASy, EBI, Israel, Japan]
Perna N.T.,
Plunkett G. III,
Burland V.,
Mau B.,
Glasner J.D.,
Rose D.J.,
Mayhew G.F.,
Evans P.S.,
Gregor J.,
Kirkpatrick H.A.,
Posfai G.,
Hackett J.,
Klink S.,
Boutin A.,
Shao Y.,
Miller L.,
Grotbeck E.J.,
Davis N.W.,
Lim A., ![]()
Dimalanta E.T.,
Potamousis K.,
Apodaca J.,
Anantharaman T.S.,
Lin J.,
Yen G.,
Schwartz D.C.,
Welch R.A.,
Blattner F.R.;
"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
Nature 409:529-533(2001).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
DOI=10.1093/dnares/8.1.11; PubMed=11258796 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi T.,
Makino K.,
Ohnishi M.,
Kurokawa K.,
Ishii K.,
Yokoyama K.,
Han C.-G.,
Ohtsubo E.,
Nakayama K.,
Murata T.,
Tanaka M.,
Tobe T.,
Iida T.,
Takami H.,
Honda T.,
Sasakawa C.,
Ogasawara N.,
Yasunaga T.,
Kuhara S., ![]()
Shiba T.,
Hattori M.,
Shinagawa H.;
"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.";
DNA Res. 8:11-22(2001).
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- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. This enzyme is also a chemoreceptor monitoring the environment for changes in sugar concentration (By similarity).
- CATALYTIC ACTIVITY: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.
- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
- DOMAIN: The EIIC domain forms the PTS system translocation channel and contains the specific substrate-binding site.
- DOMAIN: The EIIB domain is phosphorylated by phospho-EIIA on a cysteinyl or histidyl residue, depending on the transported sugar. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the EIIC domain.
- SIMILARITY: Contains 1 PTS EIIB type-1 domain.
- SIMILARITY: Contains 1 PTS EIIC type-1 domain.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 477 AA [This is the length of the unprocessed precursor] |
Molecular weight: 50677 Da [This is the MW of the unprocessed precursor] |
CRC64: D97A80FD64B74F73 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MFKNAFANLQ KVGKSLMLPV SVLPIAGILL GVGSANFSWL PAVVSHVMAE AGGSVFANMP
70 80 90 100 110 120
LIFAIGVALG FTNNDGVSAL AAVVAYGIMV KTMAVVAPLV LHLPAEEIAS KHLADTGVLG
130 140 150 160 170 180
GIISGAIAAY MFNRFYRIKL PEYLGFFAGK RFVPIISGLA AIFTGVVLSF IWPPIGSAIQ
190 200 210 220 230 240
TFSQWAAYQN PVVAFGIYGF IERCLVPFGL HHIWNVPFQM QIGEYTNAAG QVFHGDIPRY
250 260 270 280 290 300
MAGDPTAGKL SGGFLFKMYG LPAAAIAIWH SAKPENRAKV GGIMISAALT SFLTGITEPI
310 320 330 340 350 360
EFSFMFVAPI LYIIHAILAG LAFPICILLG MRDGTSFSHG LIDFIVLSGN SSKLWLFPIV
370 380 390 400 410 420
GIGYAIVYYT IFRVLIKALD LKTPGREDAT EDAKATGTSE MAPALVAAFG GKENITNLDA
430 440 450 460 470
CITRLRVSVA DVSKVDQAGL KKLGAAGVVV AGSGVQAIFG TKSDNLKTEM DEYIRNH
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P69788 in FASTA format |
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