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UniProtKB/Swiss-Prot entry P68850

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SYFA_STAAW
Primary accession number P68850
Secondary accession number Q99QR1
Integrated into Swiss-Prot on December 21, 2004
Sequence was last modified on December 21, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 24)
Name and origin of the protein
Protein name Phenylalanyl-tRNA synthetase alpha chain
Synonyms EC 6.1.1.20
Phenylalanine--tRNA ligase alpha chain
PheRS
Gene name
Name: pheS
OrderedLocusNames: MW1021
From
Staphylococcus aureus (strain MW2) [TaxID: 196620] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(02)08713-5; PubMed=12044378 [NCBI, ExPASy, EBI, Israel, Japan]
Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
"Genome and virulence determinants of high virulence community-acquired MRSA.";
Lancet 359:1819-1827(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000033; BAB94886.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_645838.1; -.
3D structure databases
HSSP P27001; 1JJC. [HSSP ENTRY / PDB]
ModBase P68850.
Enzyme and pathway databases
BioCyc SAUR196620:MW1021-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from HAMAP).
GO:0004826; Molecular function: phenylalanine-tRNA ligase activity (inferred from electronic annotation from HAMAP).
GO:0006432; Biological process: phenylalanyl-tRNA aminoacylation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00281; -; 1.
PBIL [Tree]
InterPro IPR006195; aa-tRNA-synth_II.
IPR002319; Phe-tRNA-synth_IIc.
IPR004529; Phe-tRNA-synth_IIc_asu.
IPR004188; Phe-tRNA_synth_II_N.
Graphical view of domain structure.
PANTHER PTHR11538; tRNA-synt_2d; 1.
Pfam PF02912; Phe_tRNA-synt_N; 1.
PF01409; tRNA-synt_2d; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00468; pheS; 1.
PROSITE PS50862; AA_TRNA_LIGASE_II; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet P68850.
Genome annotation databases
GeneID 1003133; -.
GenomeReviews BA000033_GR; MW1021.
KEGG sam:MW1021; -.
Phylogenomic databases
HOGENOM P68850; -.
Other
BindingDB P68850; -.
Genome annotation databases
CMR P68850; MW1021.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Protein biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   352  352     Phenylalanyl-tRNA synthetase alpha chain. PRO_0000126765
METAL   258   258        Magnesium (By similarity). 
Sequence information
Length: 352 AA [This is the length of the unprocessed precursor] Molecular weight: 40121 Da [This is the MW of the unprocessed precursor] CRC64: 01FD437729B8FDF7 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSEQQTMSEL KQQALVDINE ANDERALQEV KVKYLGKKGS VSGLMKLMKD LPNEEKPAFG 

        70         80         90        100        110        120 
QKVNELRQTI QNELDERQQM LVKEKLNKQL AEETIDVSLP GRHIEIGSKH PLTRTIEEIE 

       130        140        150        160        170        180 
DLFLGLGYEI VNGYEVEQDH YNFEMLNLPK SHPARDMQDS FYITDEILLR THTSPVQART 

       190        200        210        220        230        240 
MESRHGQGPV KIICPGKVYR RDSDDATHSH QFTQIEGLVV DKNVKMSDLK GTLELLAKKL 

       250        260        270        280        290        300 
FGADREIRLR PSYFPFTEPS VEVDVSCFKC KGKGCNVCKH TGWIEILGAG MVHPNVLEMA 

       310        320        330        340        350 
GFDSSEYSGF AFGMGPDRIA MLKYGIEDIR HFYTNDVRFL DQFKAVEDRG DM
P68850 in FASTA format

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