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UniProtKB/Swiss-Prot entry P68585


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MTBP_BACSU
Primary accession number P68585
Secondary accession number P05795
Integrated into Swiss-Prot on December 7, 2004
Sequence was last modified on December 7, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 23)
Name and origin of the protein
Protein name Phi-3T prophage-derived modification methylase Phi3TI
Synonyms M.Phi3TI
EC 2.1.1.37
Cytosine-specific methyltransferase Phi3TI
Gene name
Name: mtbP
OrderedLocusNames: BSU20250
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z99114; CAB13917.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_389907.1; -.
3D structure databases
HSSP P05102; 6MHT. [HSSP ENTRY / PDB]
ModBase P68585.
Protein family/group databases
REBASE 3140; M.BsuMIIP.
Enzyme and pathway databases
BioCyc BSUB224308:BSU2025-MON; -.
Organism-specific databases
SubtiList BG12627; mtbP. [Micado]
Ontologies
GO
GO:0003886; Molecular function: DNA (cytosine-5-)-methyltransferase activity (inferred from electronic annotation from EC).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0006306; Biological process: DNA methylation (inferred from electronic annotation from InterPro).
GO:0009307; Biological process: DNA restriction-modification system (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001525; C5_DNA_meth.
Graphical view of domain structure.
PANTHER PTHR10629; C5_DNA_meth; 1.
Pfam PF00145; DNA_methylase; 2.
Pfam graphical view of domain structure.
PRINTS PR00105; C5METTRFRASE.
TIGRFAMs TIGR00675; dcm; 1.
PROSITE PS00094; C5_MTASE_1; 1.
PS00095; C5_MTASE_2; 1.
ProtoNet P68585.
Genome annotation databases
GeneID 939532; -.
GenomeReviews AL009126_GR; BSU20250.
KEGG bsu:BSU20250; -.
NMPDR fig|224308.1.peg.2030; -.
Phylogenomic databases
HOGENOM P68585; -.
Genome annotation databases
CMR P68585; BSU20250.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Methyltransferase; Restriction system; S-adenosyl-L-methionine; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   443  443     Phi-3T prophage-derived modification methylase Phi3TI. PRO_0000087865
ACT_SITE   78    78        By similarity. 
Sequence information
Length: 443 AA [This is the length of the unprocessed precursor] Molecular weight: 50510 Da [This is the MW of the unprocessed precursor] CRC64: 2BF02005159E9879 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSKLRVMSLF SGIGAFEAAL RNIGVDYELI GFSEIDKYAI KSYCAIHNVS ETLNVGDISK 

        70         80         90        100        110        120 
AKKDNIPYFD LLTSGFPCPT FSVAGGRDGM EYKCSNCSHE HLITYEDYKK GVKCPKCEAV 

       130        140        150        160        170        180 
SKAKDERGTL FFETALLAEE KKPKFVILEN VKGLINSGNG QVLRIISETM NNIGYRIDLE 

       190        200        210        220        230        240 
LLNSKFFNVP QNRERVYIIG IREDLVENEQ WVVGQKRNDV LSKGKKRLQE INIKSFNFKW 

       250        260        270        280        290        300 
PLQDTVTKRL REILEDFVDE KYYLNEEKTK KLVEQLGTAP LQKQEVREPL MVGHVDLKGH 

       310        320        330        340        350        360 
DAIKRVYSPE GLSPTLTTMG GGHREPKIAE KQKEVRAVLT PEREEKRQNG RRFKENGEPA 

       370        380        390        400        410        420 
FTVNTIDRHG VAIGEYPKYK IRKLSPLECW RLQAFDDEDF EKAFAAGISN SQLYKQAGNS 

       430        440 
ITVSVLESIF QELIHTYVNK ESE 

P68585 in FASTA format

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