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UniProtKB/Swiss-Prot entry P68082

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MYG_HORSE
Primary accession number P68082
Secondary accession number P02188
Integrated into Swiss-Prot on July 21, 1986
Sequence was last modified on January 23, 2007 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 33)
Name and origin of the protein
Protein name Myoglobin
Synonyms None
Gene name
Name: MB
From
Equus caballus (Horse) [TaxID: 9796] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Protein existence 1: Evidence at protein level;
References
[1]
 PROTEIN SEQUENCE OF 2-154.
TISSUE=Heart muscle;
PubMed=4902609 [NCBI, ExPASy, EBI, Israel, Japan]
Dautrevaux M., Boulanger Y., Han K., Biserte G.;
"Covalent structure of horse myoglobin.";
Eur. J. Biochem. 11:267-277(1969).
[2]
 PROTEIN SEQUENCE OF 2-154.
TISSUE=Skeletal muscle;
Romero-Herrera A.E., Lehmann H.;
"Residue 122 of sperm whale and horse myoglobin.";
Biochim. Biophys. Acta 336:318-323(1974).
[3]
 PROTEIN SEQUENCE OF 2-16 AND 57-71.
DOI=10.1016/0006-291X(90)91922-F; PubMed=2302197 [NCBI, ExPASy, EBI, Israel, Japan]
Jahnen W., Ward L.D., Reid G.E., Moritz R.L., Simpson R.J.;
"Internal amino acid sequencing of proteins by in situ cyanogen bromide cleavage in polyacrylamide gels.";
Biochem. Biophys. Res. Commun. 166:139-145(1990).
[4]
 X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).
DOI=10.1016/S0022-2836(05)80270-0; PubMed=2359126 [NCBI, ExPASy, EBI, Israel, Japan]
Evans S.V., Brayer G.D.;
"High-resolution study of the three-dimensional structure of horse heart metmyoglobin.";
J. Mol. Biol. 213:885-897(1990).
[5]
 X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS).
PubMed=3346247 [NCBI, ExPASy, EBI, Israel, Japan]
Evans S.V., Brayer G.D.;
"Horse heart metmyoglobin. A 2.8-A resolution three-dimensional structure determination.";
J. Biol. Chem. 263:4263-4268(1988).
[6]
 X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF MUTANT THR-65.
DOI=10.1021/bi00033a021; PubMed=7654702 [NCBI, ExPASy, EBI, Israel, Japan]
Bogumil R., Maurus R., Hildebrand D.P., Brayer G.D., Mauk A.G.;
"Origin of the pH-dependent spectroscopic properties of pentacoordinate metmyoglobin variants.";
Biochemistry 34:10483-10490(1995).
[7]
 X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).
DOI=10.1038/35002641; PubMed=10706294 [NCBI, ExPASy, EBI, Israel, Japan]
Chu K., Vojtchovsky J., McMahon B.H., Sweet R.M., Berendzen J., Schlichting I.;
"Structure of a ligand-binding intermediate in wild-type carbonmonoxy myoglobin.";
Nature 403:921-923(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
PIR A91098; MYHO.
RefSeq XP_001500028.1; -.
3D structure databases
PDB
1AZI; X-ray; 2.00 A; A=1-154.[ExPASy / RCSB / EBI]
1BJE; X-ray; 1.80 A; A=1-154.[ExPASy / RCSB / EBI]
1DWR; X-ray; 1.45 A; A=1-154.[ExPASy / RCSB / EBI]
1DWS; X-ray; 1.45 A; A=1-154.[ExPASy / RCSB / EBI]
1DWT; X-ray; 1.40 A; A=1-154.[ExPASy / RCSB / EBI]
1GJN; X-ray; 1.35 A; A=1-154.[ExPASy / RCSB / EBI]
1HRM; X-ray; 1.70 A; A=1-154.[ExPASy / RCSB / EBI]
1HSY; X-ray; 1.90 A; A=1-154.[ExPASy / RCSB / EBI]
1NPF; X-ray; 1.90 A; A=1-154.[ExPASy / RCSB / EBI]
1NPG; X-ray; 1.70 A; A=1-154.[ExPASy / RCSB / EBI]
1NZ2; X-ray; 1.90 A; A=1-154.[ExPASy / RCSB / EBI]
1NZ3; X-ray; 1.60 A; A=1-154.[ExPASy / RCSB / EBI]
1NZ4; X-ray; 1.80 A; A=1-154.[ExPASy / RCSB / EBI]
1NZ5; X-ray; 1.70 A; A=1-154.[ExPASy / RCSB / EBI]
1RSE; X-ray; 1.70 A; A=1-154.[ExPASy / RCSB / EBI]
1WLA; X-ray; 1.70 A; A=1-154.[ExPASy / RCSB / EBI]
1XCH; X-ray; 1.70 A; A=1-154.[ExPASy / RCSB / EBI]
1YMA; X-ray; 2.00 A; A=1-154.[ExPASy / RCSB / EBI]
1YMB; X-ray; 1.90 A; A=1-154.[ExPASy / RCSB / EBI]
1YMC; X-ray; 2.00 A; A=1-154.[ExPASy / RCSB / EBI]
2FRF; X-ray; 1.20 A; A=2-154.[ExPASy / RCSB / EBI]
2FRI; X-ray; 1.60 A; X=2-154.[ExPASy / RCSB / EBI]
2FRJ; X-ray; 1.30 A; X=2-154.[ExPASy / RCSB / EBI]
2FRK; X-ray; 1.30 A; X=2-154.[ExPASy / RCSB / EBI]
2IN4; X-ray; 2.15 A; A=1-154.[ExPASy / RCSB / EBI]
2NSR; X-ray; 1.90 A; A=2-154.[ExPASy / RCSB / EBI]
2NSS; X-ray; 2.00 A; A=2-154.[ExPASy / RCSB / EBI]
2O58; X-ray; 1.65 A; X=2-154.[ExPASy / RCSB / EBI]
2O5B; X-ray; 2.00 A; X=2-154.[ExPASy / RCSB / EBI]
2O5L; X-ray; 1.70 A; X=2-154.[ExPASy / RCSB / EBI]
2O5M; X-ray; 1.65 A; X=2-154.[ExPASy / RCSB / EBI]
2O5O; X-ray; 1.60 A; X=2-154.[ExPASy / RCSB / EBI]
2O5Q; X-ray; 1.90 A; X=2-154.[ExPASy / RCSB / EBI]
2O5S; X-ray; 1.60 A; X=2-154.[ExPASy / RCSB / EBI]
2O5T; X-ray; 1.60 A; X=2-154.[ExPASy / RCSB / EBI]
2V1E; X-ray; 1.30 A; A=2-154.[ExPASy / RCSB / EBI]
2V1F; X-ray; 1.20 A; A=2-154.[ExPASy / RCSB / EBI]
2V1G; X-ray; 1.35 A; A=2-154.[ExPASy / RCSB / EBI]
2V1H; X-ray; 1.30 A; A=2-154.[ExPASy / RCSB / EBI]
2V1I; X-ray; 1.20 A; A=2-154.[ExPASy / RCSB / EBI]
2V1J; X-ray; 1.40 A; A=2-154.[ExPASy / RCSB / EBI]
2V1K; X-ray; 1.25 A; A=2-154.[ExPASy / RCSB / EBI]
2VLY; X-ray; 1.60 A; A=2-154.[ExPASy / RCSB / EBI]
2VLZ; X-ray; 1.50 A; A=2-154.[ExPASy / RCSB / EBI]
2VM0; X-ray; 1.60 A; A=2-154.[ExPASy / RCSB / EBI]
Detailed list of linked structures.
PDBsum 1AZI; -.
1BJE; -.
1DWR; -.
1DWS; -.
1DWT; -.
1GJN; -.
1HRM; -.
1HSY; -.
1NPF; -.
1NPG; -.
1NZ2; -.
1NZ3; -.
1NZ4; -.
1NZ5; -.
1RSE; -.
1WLA; -.
1XCH; -.
1YMA; -.
1YMB; -.
1YMC; -.
2FRF; -.
2FRI; -.
2FRJ; -.
2FRK; -.
2IN4; -.
2NSR; -.
2NSS; -.
2O58; -.
2O5B; -.
2O5L; -.
2O5M; -.
2O5O; -.
2O5Q; -.
2O5S; -.
2O5T; -.
2V1E; -.
2V1F; -.
2V1G; -.
2V1H; -.
2V1I; -.
2V1J; -.
2V1K; -.
2VLY; -.
2VLZ; -.
2VM0; -.
ModBase P68082.
Family and domain databases
InterPro IPR012292; Globin.
IPR000971; Globin_subset.
IPR002335; Myoglobin.
Graphical view of domain structure.
Gene3D G3DSA:1.10.490.10; Globin_related; 1.
PANTHER PTHR11442:SF5; Myoglobin; 1.
Pfam PF00042; Globin; 1.
Pfam graphical view of domain structure.
PRINTS PR00613; MYOGLOBIN.
PROSITE PS01033; GLOBIN; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P68082.
Genome annotation databases
GeneID 100054434; -.
Phylogenomic databases
HOVERGEN P68082; -.
Other
LinkHub P68082; -.
ProtoNet P68082.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Direct protein sequencing; Heme; Iron; Metal-binding; Muscle protein; Oxygen transport; Transport.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   154  153     Myoglobin. PRO_0000053302
METAL   65    65        Iron (heme distal ligand). 
METAL   94    94        Iron (heme proximal ligand). 
CONFLICT   123   123        D -> N (in Ref. 1; AA sequence). 
HELIX   5    20  16      
HELIX   22    36  15      
HELIX   38    41  4      
TURN   45    49  5      
HELIX   53    57  5      
HELIX   60    77  18      
TURN   78    81  4      
HELIX   84    96  13      
HELIX   102   119  18      
HELIX   126   150  25      
Sequence information
Length: 154 AA [This is the length of the unprocessed precursor] Molecular weight: 17083 Da [This is the MW of the unprocessed precursor] CRC64: 20EABC4A66ACE975 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MGLSDGEWQQ VLNVWGKVEA DIAGHGQEVL IRLFTGHPET LEKFDKFKHL KTEAEMKASE 

        70         80         90        100        110        120 
DLKKHGTVVL TALGGILKKK GHHEAELKPL AQSHATKHKI PIKYLEFISD AIIHVLHSKH 

       130        140        150 
PGDFGADAQG AMTKALELFR NDIAAKYKEL GFQG
P68082 in FASTA format

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