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UniProtKB/Swiss-Prot entry P67069


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HASC2_STRP3
Primary accession number P67069
Secondary accession number P58098
Integrated into Swiss-Prot on October 11, 2004
Sequence was last modified on October 11, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 23)
Name and origin of the protein
Protein name UTP--glucose-1-phosphate uridylyltransferase 2
Synonyms EC 2.7.7.9
UDP-glucose pyrophosphorylase 2
UDPGP 2
Alpha-D-glucosyl-1-phosphate uridylyltransferase 2
Uridine diphosphoglucose pyrophosphorylase 2
Gene name
Name: hasC2
Synonyms: hasC.2
OrderedLocusNames: SpyM3_0160, SPs0166
From
Streptococcus pyogenes serotype M3 [TaxID: 301448] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-595 / MGAS315 / Serotype M3;
DOI=10.1073/pnas.152298499; PubMed=12122206 [NCBI, ExPASy, EBI, Israel, Japan]
Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D., Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S., Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
"Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence.";
Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SSI-1 / Serotype M3;
DOI=10.1101/gr.1096703; PubMed=12799345 [NCBI, ExPASy, EBI, Israel, Japan]
Nakagawa I., Kurokawa K., Yamashita A., Nakata M., Tomiyasu Y., Okahashi N., Kawabata S., Yamazaki K., Shiba T., Yasunaga T., Hayashi H., Hattori M., Hamada S.;
"Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.";
Genome Res. 13:1042-1055(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014074; AAM78767.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BA000034; BAC63261.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_663964.1; -.
NP_801428.1; -.
3D structure databases
ModBase P67069.
Enzyme and pathway databases
BioCyc SPYO193567:SPS0166-MON; -.
SPYO198466:SPYM3_0160-MON; -.
Ontologies
GO
GO:0003983; Molecular function: UTP:glucose-1-phosphate uridylyltransferase activity (inferred from electronic annotation from InterPro).
GO:0009058; Biological process: biosynthetic process (inferred from electronic annotation from InterPro).
GO:0006011; Biological process: UDP-glucose metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR005771; GalU_trans_bac.
IPR005835; NTP_transferase.
Graphical view of domain structure.
Pfam PF00483; NTP_transferase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01099; galU; 1.
ProtoNet P67069.
Genome annotation databases
GeneID 1008474; -.
1065625; -.
GenomeReviews BA000034_GR; SPs0166.
AE014074_GR; SpyM3_0160.
KEGG spg:SpyM3_0160; -.
sps:SPs0166; -.
Phylogenomic databases
HOGENOM P67069; -.
Genome annotation databases
CMR P67069; SpyM3_0160.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   299  299     UTP--glucose-1-phosphate uridylyltransferase 2. PRO_0000201373
Sequence information
Length: 299 AA [This is the length of the unprocessed precursor] Molecular weight: 33302 Da [This is the MW of the unprocessed precursor] CRC64: D927314E58F6091B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTKVRKAIIP AAGLGTRFLP ATKALAKEML PIVDKPTIQF IVEEALKSGI EEILIVTGKS 

        70         80         90        100        110        120 
KRSIEDHFDS NFELEYNLQA KGKIELLKLV DETTSINLHF IRQSHPRGLG DAVLQAKTFV 

       130        140        150        160        170        180 
GNEPFVVMLG DDLMDITNPN VKPLTKQLID DYEETHAATI AVMRVPHEDV SNYGIIAPQA 

       190        200        210        220        230        240 
KAVKGLYSVD TFVEKPQPQD APSDLAIIGR YLLTPEIFSI LEKQEPGAGN EVQLTDAIDT 

       250        260        270        280        290 
LNKTQRVFAR EFKGKRYDVG DKFGFMKTSL DYALKHPQVK DDLKAYIIQL GKALEKTKP 

P67069 in FASTA format

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