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UniProtKB/Swiss-Prot entry P65611


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRB_BRUME
Primary accession number P65611
Secondary accession number Q8YC62
Integrated into Swiss-Prot on October 11, 2004
Sequence was last modified on October 11, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 27)
Name and origin of the protein
Protein name Aspartate carbamoyltransferase
Synonyms EC 2.1.3.2
Aspartate transcarbamylase
ATCase
Gene name
Name: pyrB
OrderedLocusNames: BMEII0670
From
Brucella melitensis [TaxID: 29459] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Brucella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=16M / ATCC 23456 / NCTC 10094 / Biotype 1;
DOI=10.1073/pnas.221575398; PubMed=11756688 [NCBI, ExPASy, EBI, Israel, Japan]
DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R.;
"The genome sequence of the facultative intracellular pathogen Brucella melitensis.";
Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE009702; AAL53912.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AE3593; AE3593.
RefSeq NP_541648.1; -.
3D structure databases
HSSP P00479; 3CSU. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
ModBase P65611.
Enzyme and pathway databases
BioCyc BMEL224914:BMEII0670-MON; -.
Ontologies
GO
GO:0004070; Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00001; -; 1.
PBIL [Tree]
InterPro IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.
Pfam PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.
PRINTS PR00100; AOTCASE.
PR00101; ATCASE.
TIGRFAMs TIGR00670; asp_carb_tr; 1.
PROSITE PS00097; CARBAMOYLTRANSFERASE; 1.
BLOCKS P65611.
Genome annotation databases
GeneID 1198442; -.
GenomeReviews AE008918_GR; BMEII0670.
KEGG bme:BMEII0670; -.
Phylogenomic databases
HOGENOM P65611; -.
Genome annotation databases
CMR P65611; BMEII0670.
Other
ProtoNet P65611.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Pyrimidine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   322  322     Aspartate carbamoyltransferase. PRO_0000113108
Sequence information
Length: 322 AA [This is the length of the unprocessed precursor] Molecular weight: 34802 Da [This is the MW of the unprocessed precursor] CRC64: 81B6208851B9521B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTNQTVSPLF PHRHLLGIKG LSPLDILCLL DLADQEIAVS RQPEKKKSVL RGRTQINLFF 

        70         80         90        100        110        120 
EASTRTQSSF ELAGKRLGAD VMNMSVGNSS VKKGETLIDT AMTLNAMQPD ILVIRHASAG 

       130        140        150        160        170        180 
AAALLAQKVG CSVVNAGDGA HEHPTQALLD ALTIRRAKGQ IENLIVAICG DVLHSRVARS 

       190        200        210        220        230        240 
NILLLNALGA RVRVVAPSTL LPAGMADMSV EVFNSMEEGL KDADVVMMLR LQRERMAGSF 

       250        260        270        280        290        300 
VPSVREYFHF YGLDREKLKF AKPDALVMHP GPMNRGVEIA SDVADGPQSV IQQQVEMGVA 

       310        320 
VRMAVMEALL DPRRNPGNGE PA 

P65611 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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