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UniProtKB/Swiss-Prot entry P61078


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UB2D3_RAT
Primary accession number P61078
Secondary accession number P47986
Integrated into Swiss-Prot on April 26, 2004
Sequence was last modified on April 26, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 40)
Name and origin of the protein
Protein name Ubiquitin-conjugating enzyme E2 D3
Synonyms EC 6.3.2.19
Ubiquitin-protein ligase D3
Ubiquitin carrier protein D3
Ubiquitin-conjugating enzyme E2-17 kDa 3
E2(17)KB 3
Phosphoarginine phosphatase
PAPase
Gene name
Name: Ube2d3
From
Rattus norvegicus (Rat) [TaxID: 10116] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Testis;
PubMed=7826319 [NCBI, ExPASy, EBI, Israel, Japan]
Wing S.S., Jain P.;
"Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testis.";
Biochem. J. 305:125-132(1995).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=Sprague-Dawley;
TISSUE=Liver;
Yokoi F., Hamato N., Kamei K., Hara S., Miyagi M., Tsunasawa S., Hiraishi H., Kumon A.;
"Nomega-phosphoarginine phosphatase activity of ubiquitin-conjugating enzymes type UBC4A/10A and UBC2E.";
Res. Commun. Biochem. Cell Mol. Biol. 2:331-346(1998).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Heart;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U13177; AAA85102.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U13175; AAA85100.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB006852; BAA87330.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC072696; AAH72696.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S53358; S53358.
RefSeq NP_112516.1; -.
UniGene Rn.2778
3D structure databases
HSSP P15731; 1QCQ. [HSSP ENTRY / PDB]
SMR P61078; 1-147.
ModBase P61078.
Organism-specific databases
RGD 619912; Ube2d3.
Gene expression databases
ArrayExpress P61078; -.
GermOnline ENSRNOG00000013741; Rattus norvegicus.
Family and domain databases
InterPro IPR016135; UBQ-conjugat/RWD-like.
IPR000608; UBQ-conjugat_E2.
Graphical view of domain structure.
Gene3D G3DSA:3.10.110.10; UBQ-conjugat_E2; 1.
PANTHER PTHR11621; UBQ-conjugat_E2; 1.
Pfam PF00179; UQ_con; 1.
Pfam graphical view of domain structure.
ProDom PD000461; UBQ_conjugat; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00212; UBCc; 1.
SMART graphical view of domain structure.
PROSITE PS00183; UBIQUITIN_CONJUGAT_1; 1.
PS50127; UBIQUITIN_CONJUGAT_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P61078.
Genome annotation databases
Ensembl ENSRNOG00000013741; Rattus norvegicus. [Contig view]
GeneID 81920; -.
KEGG rno:81920; -.
Phylogenomic databases
HOVERGEN P61078; -.
Other
ProtoNet P61078.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Ligase; Ubl conjugation pathway.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   147  147     Ubiquitin-conjugating enzyme E2 D3. PRO_0000082468
ACT_SITE   85    85        Glycyl thioester intermediate (By similarity). 
Sequence information
Length: 147 AA [This is the length of the unprocessed precursor] Molecular weight: 16687 Da [This is the MW of the unprocessed precursor] CRC64: ADD74A8A708EFEE3 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 

        70         80         90        100        110        120 
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 

       130        140 
PEIARIYKTD RDKYNRISRE WTQKYAM 

P61078 in FASTA format

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