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UniProtKB/Swiss-Prot entry P57405


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_BUCAI
Primary accession number P57405
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on December 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 46)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: zwf
OrderedLocusNames: BU320
From
Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [TaxID: 118099] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Tokyo 1998;
DOI=10.1038/35024074; PubMed=10993077 [NCBI, ExPASy, EBI, Israel, Japan]
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS.";
Nature 407:81-86(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000003; BAB13028.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_240142.1; -.
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase P57405.
Enzyme and pathway databases
BioCyc BSP107806:BU320-MON; -.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
BLOCKS P57405.
Genome annotation databases
GeneID 1110019; -.
GenomeReviews BA000003_GR; BU320.
KEGG buc:BU320; -.
Phylogenomic databases
HOGENOM P57405; -.
Genome annotation databases
CMR P57405; BU320.
Other
ProtoNet P57405.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Complete proteome; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   491  491     Glucose-6-phosphate 1-dehydrogenase. PRO_0000068112
ACT_SITE   238   238        Proton acceptor (By similarity). 
BINDING   17    17        NADP (By similarity). 
BINDING   49    49        NADP (By similarity). 
BINDING   176   176        Substrate (By similarity). 
BINDING   180   180        Substrate (By similarity). 
BINDING   343   343        Substrate (By similarity). 
Sequence information
Length: 491 AA [This is the length of the unprocessed precursor] Molecular weight: 57218 Da [This is the MW of the unprocessed precursor] CRC64: 3DFAE2D26EB690F2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MIIETNHACD LVIFGAKGDL TKRKLLPALY KLEKSKKIHK YTRIIASGRA DWSTEDYIEK 

        70         80         90        100        110        120 
IKTEVKNFLN EEINDLIWKN LSSRIFFCNI DVHEPLHFFR LKTILKQKKN IIVYYCAVPS 

       130        140        150        160        170        180 
NTLNSIFIGL GNAHLNSVPS RIVLEKPLGV CLKTSKKIND QISKYFLESQ IFRIDHYLGK 

       190        200        210        220        230        240 
ESILNLFALR FSNTCLFYNW NNKTIDHIQI TVSEEVGIED RWNYFNMMGQ MKDMVQNHLL 

       250        260        270        280        290        300 
QILTILTMDQ PKNISSESIQ HEKVKILRSL NPINIHNINK KTVRGQYCSG VINEKKVPSY 

       310        320        330        340        350        360 
LEENGANKNS LTETFVAIKV DLNNKQWSGV PFYLRTGKRL AHKYSEIVVF FKKKPTNLFK 

       370        380        390        400        410        420 
NLNSELLQNK LIIRLEPNPN IIFDFSVKAP GLEQEYKIEN SQLKSSQFSK KYSKNSIDAY 

       430        440        450        460        470        480 
ERLLFEIMRG VQSLFVCRDE IEAAWKWIDP IIHAWKNSKN NAPQLYMSGT WGPKNSDLLL 

       490 
AHDGRVWYEF H 

P57405 in FASTA format

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