ID   XG_HUMAN                Reviewed;         180 AA.
AC   P55808; Q71BZ5;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   22-JUL-2008, entry version 60.
DE   RecName: Full=Glycoprotein Xg;
DE   AltName: Full=Protein PBDX;
DE   Flags: Precursor;
GN   Name=XG; Synonyms=PBDX;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Bone marrow;
RX   MEDLINE=94332149; PubMed=8054981; DOI=10.1038/ng0494-394;
RA   Ellis N.A., Ye T.Z., Patton S., German J., Goodfellow P.N., Weller P.;
RT   "Cloning of PBDX, an MIC2-related gene that spans the pseudoautosomal
RT   boundary on chromosome Xp.";
RL   Nat. Genet. 6:394-400(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Naoko S., Fujiki K., Kanai A., Tanaka Y., Iwata T.;
RT   "Identification of PBDX gene highly expressed in human cornea.";
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Naoko S., Tanaka Y., Iwata T.;
RT   "Molecular cloning and characterization of mouse PBDX.";
RL   Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
CC       protein (Potential).
CC   -!- PTM: O-glycosylated (Probable).
CC   -!- POLYMORPHISM: XG is responsible for the Xg blood group system.
CC   -!- MISCELLANEOUS: The gene encoding for this protein is located in
CC       the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.
CC   -!- SIMILARITY: Belongs to the CD99 family.
CC   -!- CAUTION: Ref.3 sequence incorrectly indicated as originating from
CC       mouse.
CC   -!- WEB RESOURCE: Name=BGMUT; Note=Blood group antigen gene mutation
CC       database";
CC       URL="http://www.ncbi.nlm.nih.gov/projects/mhc/xslcgi.fcgi?cmd=bgmut/systems_info&system=xg";
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DR   EMBL; X96421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AF380356; AAL04055.1; -; mRNA.
DR   EMBL; AF534880; AAN03481.1; -; mRNA.
DR   PIR; S43791; S43791.
DR   RefSeq; NP_780778.1; -.
DR   UniGene; Hs.179675; -.
DR   PhosphoSite; P55808; -.
DR   Ensembl; ENSG00000124343; Homo sapiens.
DR   GeneID; 7499; -.
DR   KEGG; hsa:7499; -.
DR   NMPDR; fig|9606.3.peg.32391; -.
DR   H-InvDB; HIX0056172; -.
DR   HGNC; HGNC:12806; XG.
DR   MIM; 314700; gene+phenotype.
DR   PharmGKB; PA37405; -.
DR   HOVERGEN; P55808; -.
DR   LinkHub; P55808; -.
DR   ArrayExpress; P55808; -.
DR   CleanEx; HS_XG; -.
DR   GermOnline; ENSG00000124343; Homo sapiens.
DR   GO; GO:0016020; C:membrane; NAS:UniProtKB.
PE   2: Evidence at transcript level;
KW   Blood group antigen; Glycoprotein; Membrane; Signal; Transmembrane.
FT   SIGNAL        1     21       Potential.
FT   CHAIN        22    180       Glycoprotein Xg.
FT                                /FTId=PRO_0000022693.
FT   TOPO_DOM     22    142       Extracellular (Potential).
FT   TRANSMEM    143    163       Potential.
FT   TOPO_DOM    164    180       Cytoplasmic (Potential).
SQ   SEQUENCE   180 AA;  19723 MW;  DADAA9E6859C4530 CRC64;
     MESWWGLPCL AFLCFLMHAR GQRDFDLADA LDDPEPTKKP NSDIYPKPKP PYYPQPENPD
     SGGNIYPRPK PRPQPQPGNS GNSGGYFNDV DRDDGRYPPR PRPRPPAGGG GGGYSSYGNS
     DNTHGGDHHS TYGNPEGNMV AKIVSPIVSV VVVTLLGAAA SYFKLNNRRN CFRTHEPENV
//