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UniProtKB/Swiss-Prot entry P49077

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRB_ARATH
Primary accession number P49077
Secondary accession number Q9LTR1
Integrated into Swiss-Prot on February 1, 1996
Sequence was last modified on July 11, 2001 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 66)
Name and origin of the protein
Protein name Aspartate carbamoyltransferase, chloroplastic [Precursor]
Synonyms EC 2.1.3.2
Aspartate transcarbamylase
ATCase
Gene name
Name: PYRB
OrderedLocusNames: At3g20330
ORFNames: MQC12.7
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1007/BF00280183; PubMed=8041358 [NCBI, ExPASy, EBI, Israel, Japan]
Nasr F., Bertauche N., Dufour M.E., Minet M., Lacroute F.;
"Heterospecific cloning of Arabidopsis thaliana cDNAs by direct complementation of pyrimidine auxotrophic mutants of Saccharomyces cerevisiae. I. Cloning and sequence analysis of two cDNAs catalysing the second, fifth and sixth steps of the de novo pyrimidine biosynthesis pathway.";
Mol. Gen. Genet. 244:23-32(1994).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/7.2.131; PubMed=10819329 [NCBI, ExPASy, EBI, Israel, Japan]
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones.";
DNA Res. 7:131-135(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X71843; CAA50687.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB024036; BAB02813.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S46441; S46441.
RefSeq NP_188668.1; -.
UniGene At.20992
3D structure databases
HSSP P00479; 1GQ3. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
ModBase P49077.
Organism-specific databases
TAIR At3g20330; -.
Gene expression databases
ArrayExpress P49077; -.
GermOnline AT3G20330; Arabidopsis thaliana.
Family and domain databases
InterPro IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.
Pfam PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.
PRINTS PR00100; AOTCASE.
PR00101; ATCASE.
TIGRFAMs TIGR00670; asp_carb_tr; 1.
PROSITE PS00097; CARBAMOYLTRANSFERASE; 1.
BLOCKS P49077.
Genome annotation databases
GeneID 821577; -.
GenomeReviews BA000014_GR; AT3G20330.
KEGG ath:AT3G20330; -.
Other
ProtoNet P49077.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Allosteric enzyme; Chloroplast; Complete proteome; Plastid; Pyrimidine biosynthesis; Transferase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1     ?        Chloroplast (Potential). 
CHAIN   ?   390        Aspartate carbamoyltransferase, chloroplastic. PRO_0000020348
CONFLICT   330   330        Y -> F (in Ref. 2; CAA50687). 
Sequence information
Length: 390 AA [This is the length of the unprocessed precursor] Molecular weight: 43167 Da [This is the MW of the unprocessed precursor] CRC64: EE8C9216629E826E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSIASSLTSA TLCGASVFPK ALACSSEFPI NLPSPFESSK ICLTSFPASR DLKKNATLNL 

        70         80         90        100        110        120 
TRNVGPVRCH AMQAGTRELK KFELSDVIEG KQFDREMLSA IFDVAREMEK IEKSSSQSEI 

       130        140        150        160        170        180 
LKGYLMATLF YEPSTRTRLS FESAMKRLGG EVLTTENARE FSSAAKGETL EDTIRTVEGY 

       190        200        210        220        230        240 
SDIIVMRHFE SGAARKAAAT ANIPVINAGD GPGEHPTQAL LDVYTIQSEI GKLDGISVAL 

       250        260        270        280        290        300 
VGDLANGRTV RSLAYLLAKF KDVKIYFVSP EIVKMKDDIK DYLTSSGVEW EESSDLMEVA 

       310        320        330        340        350        360 
SKCDVVYQTR IQRERFGERL DLYEAARGKY IVDKDLLGVM QKKAIIMHPL PRLDEITADV 

       370        380        390 
DADPRAAYFR QAKNGLFIRM ALLKLLLVGW
P49077 in FASTA format

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