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UniProtKB/Swiss-Prot entry P47874


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name OMP_HUMAN
Primary accession number P47874
Secondary accession number Q562G2
Integrated into Swiss-Prot on February 1, 1996
Sequence was last modified on January 23, 2007 (Sequence version 2)
Annotations were last modified on    June 16, 2009 (Entry version 58)
Name and origin of the protein
Protein name Olfactory marker protein
Synonym Olfactory neuronal-specific protein
Gene name
Name: OMP
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1006/geno.1994.1200; PubMed=8034318 [NCBI, ExPASy, EBI, Israel, Japan]
Buiakova O.I., Rama Krishna N.S., Getchell T.V., Margolis F.L.;
"Human and rodent OMP genes: conservation of structural and regulatory motifs and cellular localization.";
Genomics 20:452-462(1994).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U01212; AAA20485.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC069115; AAH69115.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC069365; AAH69365.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00220343; -.
PIR A54261; A54261.
RefSeq NP_006180.1; -.
UniGene Hs.673853
3D structure databases
HSSP P08523; 1JYT. [HSSP ENTRY / PDB]
SMR P47874; 2-163.
ModBase P47874.
Organism-specific databases
GeneCards GC11P076491; -.
H-InvDB HIX0035996; -.
HGNC HGNC:8136; OMP.
GenAtlas OMP.
MIM 164340; gene. [NCBI / EBI]
PharmGKB PA26744; -.
Gene expression databases
CleanEx HS_OMP; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-SubCell).
GO:0005515; Molecular function: protein binding (inferred from electronic annotation from InterPro).
GO:0004871; Molecular function: signal transducer activity (inferred from electronic annotation from InterPro).
GO:0050896; Biological process: response to stimulus (inferred from electronic annotation from UniProtKB-KW).
GO:0007608; Biological process: sensory perception of smell (traceable author statement from ProtInc).
GO:0007165; Biological process: signal transduction (traceable author statement from ProtInc).
GO:0007268; Biological process: synaptic transmission (traceable author statement from ProtInc).
QuickGo view.
Family and domain databases
InterPro IPR009103; Olfactory_marker.
Graphical view of domain structure.
Gene3D G3DSA:2.60.120.390; Olfactory_marker; 1.
PANTHER PTHR15357; Olfactory_marker; 1.
Pfam PF06554; Olfactory_mark; 1.
Pfam graphical view of domain structure.
ProDom PD022055; Olfactory_marker; 1.
[Domain structure / List of seq. sharing at least 1 domain]
Proteomic databases
PRIDE P47874; -.
Genome annotation databases
GeneID 4975; -.
KEGG hsa:4975; -.
Phylogenomic databases
HOVERGEN P47874; -.
Other
NextBio 19150; -.
SOURCE OMP; Homo sapiens.
ProtoNet P47874.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; Cytoplasm; Olfaction; Polymorphism; Sensory transduction.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   163  162     Olfactory marker protein. PRO_0000058043
MOD_RES   2     2        N-acetylalanine (By similarity). 
VARIANT   26    26  1     R -> W (in dbSNP:rs2233546 [NCBI]). VAR_051254 [3D]
VARIANT   36    36  1     G -> R (in dbSNP:rs2233548 [NCBI]). VAR_051255 [3D]
Sequence information
Length: 163 AA [This is the length of the unprocessed precursor] Molecular weight: 18937 Da [This is the MW of the unprocessed precursor] CRC64: EECD8AD16E7A328E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAEDRPQQPQ LDMPLVLDQG LTRQMRLRVE SLKQRGEKRQ DGEKLLQPAE SVYRLNFTQQ 

        70         80         90        100        110        120 
QRLQFERWNV VLDKPGKVTI TGTSQNWTPD LTNLMTRQLL DPTAIFWRKE DSDAIDWNEA 

       130        140        150        160 
DALEFGERLS DLAKIRKVMY FLVTFGEGVE PANLKASVVF NQL 

P47874 in FASTA format

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