[1]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=8007985 [NCBI, ExPASy, EBI, Israel, Japan]
Murray J.M.,
Tavassoli M.,
Al-Harithy R.,
Sheldrick K.S.,
Lehmann A.R.,
Carr A.M.,
Watts F.Z.;
"Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.";
Mol. Cell. Biol. 14:4878-4888(1994).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Leukemic T-cell;
DOI=10.1016/0888-7543(95)80129-A; PubMed=7774922 [NCBI, ExPASy, EBI, Israel, Japan]
Hiraoka L.R.,
Harrington J.J.,
Gerhard D.S.,
Lieber M.R.,
Hsieh C.-L.;
"Sequence of human FEN-1, a structure-specific endonuclease, and chromosomal localization of the gene (FEN1) in mouse and human.";
Genomics 25:220-225(1995).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
NIEHS SNPs program;
Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature04632; PubMed=16554811 [NCBI, ExPASy, EBI, Israel, Japan]
Taylor T.D.,
Noguchi H.,
Totoki Y.,
Toyoda A.,
Kuroki Y.,
Dewar K.,
Lloyd C.,
Itoh T.,
Takeda T.,
Kim D.-W.,
She X.,
Barlow K.F.,
Bloom T.,
Bruford E.,
Chang J.L.,
Cuomo C.A.,
Eichler E.,
FitzGerald M.G.,
Jaffe D.B., ![]()
LaButti K.,
Nicol R.,
Park H.-S.,
Seaman C.,
Sougnez C.,
Yang X.,
Zimmer A.R.,
Zody M.C.,
Birren B.W.,
Nusbaum C.,
Fujiyama A.,
Hattori M.,
Rogers J.,
Lander E.S.,
Sakaki Y.;
"Human chromosome 11 DNA sequence and analysis including novel gene identification.";
Nature 440:497-500(2006).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Lung;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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PARTIAL PROTEIN SEQUENCE, FUNCTION, AND SUBCELLULAR LOCATION.
PubMed=7961795 [NCBI, ExPASy, EBI, Israel, Japan]
Robins P.,
Pappin D.J.C.,
Wood R.D.,
Lindahl T.;
"Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I.";
J. Biol. Chem. 269:28535-28538(1994).
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[7]
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FUNCTION, ACTIVE SITES ASP-34; ASP-86 AND ASP-181, SUBSTRATE-BINDING SITES GLU-158; GLY-231 AND ASP-233, AND MUTAGENESIS OF ASP-34; ASP-86; ARG-103; GLU-158; ASP-179; ASP-181; GLY-231 AND ASP-233.
DOI=10.1074/jbc.271.16.9173; PubMed=8621570 [NCBI, ExPASy, EBI, Israel, Japan]
Shen B.,
Nolan J.P.,
Sklar L.A.,
Park M.S.;
"Essential amino acids for substrate binding and catalysis of human flap endonuclease 1.";
J. Biol. Chem. 271:9173-9176(1996).
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[8]
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INTERACTION WITH PCNA.
DOI=10.1074/jbc.272.39.24522; PubMed=9305916 [NCBI, ExPASy, EBI, Israel, Japan]
Gary R.,
Ludwig D.L.,
Cornelius H.L.,
MacInnes M.A.,
Park M.S.;
"The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21.";
J. Biol. Chem. 272:24522-24529(1997).
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[9]
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INTERACTION WITH P300, AND ACETYLATION AT LYS-354; LYS-375; LYS-377 AND LYS-380.
DOI=10.1016/S1097-2765(01)00272-6; PubMed=11430825 [NCBI, ExPASy, EBI, Israel, Japan]
Hasan S.,
Stucki M.,
Hassa P.O.,
Imhof R.,
Gehrig P.,
Hunziker P.,
Hubscher U.,
Hottiger M.O.;
"Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300.";
Mol. Cell 7:1221-1231(2001).
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[10]
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FUNCTION, SUBSTRATE-BINDING SITES ARG-47 AND ARG-70, AND MUTAGENESIS OF ARG-29; ARG-47; ARG-70; ARG-73 AND LYS-80.
DOI=10.1074/jbc.M111941200; PubMed=11986308 [NCBI, ExPASy, EBI, Israel, Japan]
Qiu J.,
Bimston D.N.,
Partikian A.,
Shen B.;
"Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determination.";
J. Biol. Chem. 277:24659-24666(2002).
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[11]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[12]
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X-RAY CRYSTALLOGRAPHY (1.88 ANGSTROMS) OF 331-350.
DOI=10.1016/j.str.2004.09.018; PubMed=15576034 [NCBI, ExPASy, EBI, Israel, Japan]
Bruning J.B.,
Shamoo Y.;
"Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1.";
Structure 12:2209-2219(2004).
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[13]
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X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 2-380 IN COMPLEX WITH PCNA.
DOI=10.1038/sj.emboj.7600519; PubMed=15616578 [NCBI, ExPASy, EBI, Israel, Japan]
Sakurai S.,
Kitano K.,
Yamaguchi H.,
Hamada K.,
Okada K.,
Fukuda K.,
Uchida M.,
Ohtsuka E.,
Morioka H.,
Hakoshima T.;
"Structural basis for recruitment of human flap endonuclease 1 to PCNA.";
EMBO J. 24:683-693(2005).
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