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UniProtKB/Swiss-Prot entry P36938


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PGM_ECOLI
Primary accession number P36938
Secondary accession numbers None
Integrated into Swiss-Prot on June 1, 1994
Sequence was last modified on June 1, 1994 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 76)
Name and origin of the protein
Protein name Phosphoglucomutase
Synonyms PGM
EC 5.4.2.2
Glucose phosphomutase
Gene name
Name: pgm
OrderedLocusNames: b0688, JW0675
From
Escherichia coli (strain K12) [TaxID: 83333] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=K12;
PubMed=8083177 [NCBI, ExPASy, EBI, Israel, Japan]
Lu M., Kleckner N.;
"Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli.";
J. Bacteriol. 176:5847-5851(1994).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1093/dnares/3.3.137; PubMed=8905232 [NCBI, ExPASy, EBI, Israel, Japan]
Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T.;
"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.";
DNA Res. 3:137-155(1996).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
DOI=10.1126/science.277.5331.1453; PubMed=9278503 [NCBI, ExPASy, EBI, Israel, Japan]
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.;
"The complete genome sequence of Escherichia coli K-12.";
Science 277:1453-1474(1997).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1038/msb4100049; PubMed=16738553 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.";
Mol. Syst. Biol. 2:E1-E5(2006).
[5]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-20.
STRAIN=K12;
DOI=10.1016/0092-8674(94)90156-2; PubMed=8011018 [NCBI, ExPASy, EBI, Israel, Japan]
Lu M., Campbell J.L., Boye E., Kleckner N.;
"SeqA: a negative modulator of replication initiation in E. coli.";
Cell 77:413-426(1994).
[6]
CHARACTERIZATION.
PubMed=14216423 [NCBI, ExPASy, EBI, Israel, Japan]
Joshi J.G., Handler P.;
"Phosphoglucomutase. II. Purification and properties of phosphoglucomutase from Escherichia coli.";
J. Biol. Chem. 239:2741-2751(1964).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U08369; AAA57067.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U00096; AAC73782.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AP009048; BAA35337.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U07651; -; NOT_ANNOTATED_CDS; Unassigned_RNA.[EMBL / GenBank / DDBJ]
PIR G64803; G64803.
RefSeq AP_001326.1; -.
NP_415214.1; -.
3D structure databases
SMR P36938; 2-546.
ModBase P36938.
Protein-protein interaction databases
DIP DIP:10472N; -.
IntAct P36938; -.
Enzyme and pathway databases
BioCyc EcoCyc:PHOSPHOGLUCMUT-MON; -.
MetaCyc:PHOSPHOGLUCMUT-MON; -.
Organism-specific databases
EchoBASE EB2065; -.
EcoGene EG12144; pgm.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR005844; A-D-PHexomutase_a/b/a-I.
IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
IPR005845; A-D-PHexomutase_a/b/a-II.
IPR005846; A-D-PHexomutase_a/b/a-III.
IPR005843; A-D-PHexomutase_C.
IPR016066; A-D-PHexomutase_CS.
IPR005852; PGlcMutase_a-D-Glc-sp.
Graphical view of domain structure.
Gene3D G3DSA:3.40.120.10; A-D-PHexomutase_a/b/a-I/II/III; 2.
Pfam PF02878; PGM_PMM_I; 1.
PF02879; PGM_PMM_II; 1.
PF02880; PGM_PMM_III; 1.
PF00408; PGM_PMM_IV; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01132; pgm; 1.
PROSITE PS00710; PGM_PMM; 1.
BLOCKS P36938.
Genome annotation databases
GeneID 945271; -.
GenomeReviews U00096_GR; b0688.
AP009048_GR; JW0675.
KEGG ecj:JW0675; -.
eco:b0688; -.
Phylogenomic databases
HOGENOM P36938; -.
Genome annotation databases
CMR P36938; b0688.
Other
ProtoNet P36938.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Complete proteome; Glucose metabolism; Isomerase; Magnesium; Metal-binding; Phosphoprotein.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   546  546     Phosphoglucomutase. PRO_0000147809
ACT_SITE   146   146        Phosphoserine intermediate (By similarity). 
METAL   146   146        Magnesium; via phosphate group (By similarity). 
METAL   304   304        Magnesium (By similarity). 
METAL   306   306        Magnesium (By similarity). 
METAL   308   308        Magnesium (By similarity). 
Sequence information
Length: 546 AA [This is the length of the unprocessed precursor] Molecular weight: 58361 Da [This is the MW of the unprocessed precursor] CRC64: 666B6B9C2F2ECD59 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAIHNRAGQP AQQSDLINVA QLTAQYYVLK PEAGNAEHAV KFGTSGHRGS AARHSFNEPH 

        70         80         90        100        110        120 
ILAIAQAIAE ERAKNGITGP CYVGKDTHAL SEPAFISVLE VLAANGVDVI VQENNGFTPT 

       130        140        150        160        170        180 
PAVSNAILVH NKKGGPLADG IVITPSHNPP EDGGIKYNPP NGGPADTNVT KVVEDRANAL 

       190        200        210        220        230        240 
LADGLKGVKR ISLDEAMASG HVKEQDLVQP FVEGLADIVD MAAIQKAGLT LGVDPLGGSG 

       250        260        270        280        290        300 
IEYWKRIGEY YNLNLTIVND QVDQTFRFMH LDKDGAIRMD CSSECAMAGL LALRDKFDLA 

       310        320        330        340        350        360 
FANDPDYDRH GIVTPAGLMN PNHYLAVAIN YLFQHRPQWG KDVAVGKTLV SSAMIDRVVN 

       370        380        390        400        410        420 
DLGRKLVEVP VGFKWFVDGL FDGSFGFGGE ESAGASFLRF DGTPWSTDKD GIIMCLLAAE 

       430        440        450        460        470        480 
ITAVTGKNPQ EHYNELAKRF GAPSYNRLQA AATSAQKAAL SKLSPEMVSA STLAGDPITA 

       490        500        510        520        530        540 
RLTAAPGNGA SIGGLKVMTD NGWFAARPSG TEDAYKIYCE SFLGEEHRKQ IEKEAVEIVS 


EVLKNA 

P36938 in FASTA format

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