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UniProtKB/Swiss-Prot entry P31678


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name OTSB_ECOLI
Primary accession number P31678
Secondary accession numbers None
Integrated into Swiss-Prot on July 1, 1993
Sequence was last modified on February 1, 1995 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 61)
Name and origin of the protein
Protein name Trehalose-phosphatase
Synonyms EC 3.1.3.12
Trehalose 6-phosphate phosphatase
TPP
Gene name
Name: otsB
OrderedLocusNames: b1897, JW1886
From
Escherichia coli (strain K12) [TaxID: 83333] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
STRAIN=K12 / CSH7;
DOI=10.1016/0378-1119(94)90316-6; PubMed=8045430 [NCBI, ExPASy, EBI, Israel, Japan]
Kaasen I., McDougall J., Stroem A.R.;
"Analysis of the otsBA operon for osmoregulatory trehalose synthesis in Escherichia coli and homology of the OtsA and OtsB proteins to the yeast trehalose-6-phosphate synthase/phosphatase complex.";
Gene 145:9-15(1994).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1093/dnares/3.6.379; PubMed=9097040 [NCBI, ExPASy, EBI, Israel, Japan]
Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T.;
"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.";
DNA Res. 3:379-392(1996).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
DOI=10.1126/science.277.5331.1453; PubMed=9278503 [NCBI, ExPASy, EBI, Israel, Japan]
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.;
"The complete genome sequence of Escherichia coli K-12.";
Science 277:1453-1474(1997).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1038/msb4100049; PubMed=16738553 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.";
Mol. Syst. Biol. 2:E1-E5(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X69160; CAA48912.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U00096; AAC74967.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AP009048; BAA15718.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR I83401; I83401.
RefSeq AP_002516.1; -.
NP_416411.1; -.
3D structure databases
ModBase P31678.
Enzyme and pathway databases
BioCyc EcoCyc:TREHALOSEPHOSPHASYN-MON; -.
MetaCyc:TREHALOSEPHOSPHASYN-MON; -.
2D gel databases
SWISS-2DPAGE P31678; -.
Organism-specific databases
EchoBASE EB1702; -.
EcoGene EG11752; otsB.
Ontologies
GO
GO:0004805; Molecular function: trehalose-phosphatase activity (inferred from electronic annotation from EC).
GO:0005992; Biological process: trehalose biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR006379; HAD-SF_hydro_IIB.
IPR003337; Trehalose_PPase.
Graphical view of domain structure.
Pfam PF02358; Trehalose_PPase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01484; HAD-SF-IIB; 1.
TIGR00685; T6PP; 1.
BLOCKS P31678.
ProtoNet P31678.
Genome annotation databases
GeneID 946406; -.
GenomeReviews U00096_GR; b1897.
AP009048_GR; JW1886.
KEGG ecj:JW1886; -.
eco:b1897; -.
Phylogenomic databases
HOGENOM P31678; -.
Other
LinkHub P31678; -.
Genome annotation databases
CMR P31678; b1897.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Direct protein sequencing; Hydrolase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   266  266     Trehalose-phosphatase. PRO_0000058100
Sequence information
Length: 266 AA [This is the length of the unprocessed precursor] Molecular weight: 29175 Da [This is the MW of the unprocessed precursor] CRC64: 015E90EAD981B155 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTEPLTETPE LSAKYAWFFD LDGTLAEIKP HPDQVVVPDN ILQGLQLLAT ASDGALALIS 

        70         80         90        100        110        120 
GRSMVELDAL AKPYRFPLAG VHGAERRDIN GKTHIVHLPD AIARDISVQL HTVIAQYPGA 

       130        140        150        160        170        180 
ELEAKGMAFA LHYRQAPQHE DALMTLAQRI TQIWPQMALQ QGKCVVEIKP RGTSKGEAIA 

       190        200        210        220        230        240 
AFMQEAPFIG RTPVFLGDDL TDESGFAVVN RLGGMSVKIG TGATQASWRL AGVPDVWSWL 

       250        260 
EMITTALQQK RENNRSDDYE SFSRSI 

P31678 in FASTA format

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