ID   ASPG_PIG                Reviewed;          34 AA.
AC   P30918;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   04-NOV-2008, entry version 46.
DE   RecName: Full=N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase;
DE            EC=3.5.1.26;
DE   AltName: Full=Glycosylasparaginase;
DE   AltName: Full=Aspartylglucosaminidase;
DE            Short=AGA;
DE   AltName: Full=N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase;
DE   Contains:
DE     RecName: Full=Glycosylasparaginase alpha chain;
DE   Contains:
DE     RecName: Full=Glycosylasparaginase beta chain;
DE   Flags: Fragments;
GN   Name=AGA;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Liver;
RX   MEDLINE=92207183; PubMed=1554372;
RA   Tollersrud O.-K., Aronson N.N. Jr.;
RT   "Comparison of liver glycosylasparaginases from six vertebrates.";
RL   Biochem. J. 282:891-897(1992).
CC   -!- FUNCTION: Cleaves the GlcNAc-Asn bond which joins oligosaccharides
CC       to the peptide of asparagine-linked glycoproteins.
CC   -!- CATALYTIC ACTIVITY: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-
CC       asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-
CC       aspartate.
CC   -!- SUBUNIT: Heterotetramer of two alpha and two beta chains arranged
CC       as a dimer of alpha/beta heterodimers.
CC   -!- SUBCELLULAR LOCATION: Lysosome.
CC   -!- SIMILARITY: Belongs to the Ntn-hydrolase family.
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DR   HOVERGEN; P30918; -.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-KW.
DR   GO; GO:0003948; F:N4-(beta-N-acetylglucosaminyl)-L-asparagina...; IEA:EC.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase; Lysosome.
FT   CHAIN         1    >17       Glycosylasparaginase alpha chain.
FT                                /FTId=PRO_0000002337.
FT   CHAIN        18    >34       Glycosylasparaginase beta chain.
FT                                /FTId=PRO_0000002338.
FT   NON_CONS     17     18
FT   NON_TER      34     34
SQ   SEQUENCE   34 AA;  3621 MW;  A527053E8DBA8B56 CRC64;
     SXPLPLIVNT WPFKXATTIG MVVIHLKGYT AAGT
//