|
|
|
|
|
|
[1]
|
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Heart muscle;
PubMed=1618857 [NCBI, ExPASy, EBI, Israel, Japan]
Ishikawa Y.,
Katsushika S.,
Chen L.,
Halnon N.J.,
Kawabe J.,
Homcy C.J.;
"Isolation and characterization of a novel cardiac adenylylcyclase cDNA.";
J. Biol. Chem. 267:13553-13557(1992).
|
[2]
|
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
TISSUE=Heart muscle;
PubMed=8428899 [NCBI, ExPASy, EBI, Israel, Japan]
Katsushika S.,
Kawabe J.,
Homcy C.J.,
Ishikawa Y.;
"In vivo generation of an adenylylcyclase isoform with a half-molecule motif.";
J. Biol. Chem. 268:2273-2276(1993).
|
[3]
|
SEQUENCE REVISION TO N-TERMINUS.
Tomlinson J.,
Okumura S.,
Ishikawa Y.;
Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
|
[4]
|
X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 445-661 OF COMPLEX WITH G(S)-ALPHA.
DOI=10.1126/science.278.5345.1907; PubMed=9417641 [NCBI, ExPASy, EBI, Israel, Japan]
Tesmer J.J.G.,
Sunahara R.K.,
Gilman A.G.,
Sprang S.R.;
"Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.";
Science 278:1907-1916(1997).
|
[5]
|
X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 445-661 OF COMPLEX WITH G(S)-ALPHA.
DOI=10.1126/science.285.5428.756; PubMed=10427002 [NCBI, ExPASy, EBI, Israel, Japan]
Tesmer J.J.G.,
Sunahara R.K.,
Johnson R.A.,
Gosselin G.,
Gilman A.G.,
Sprang S.R.;
"Two-metal-ion catalysis in adenylyl cyclase.";
Science 285:756-760(1999).
|
|
|
|
|
|
|
|
|
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Length: 1265 AA [This is the length of the unprocessed precursor] |
Molecular weight: 140319 Da [This is the MW of the unprocessed precursor] |
CRC64: 414322F64153DFB4 [This is a checksum on the sequence] |
|
10 20 30 40 50 60
MSGPRSASPP GCAATRGGPE HRAAWGEAEA RANGHPHAAG GATRGCSKKP GGAVTPQLQQ
70 80 90 100 110 120
QQQQQQHEQQ HEQQQHEQQQ HVQQQQRLAK RWRGDDDPPL GGDDPLAGGF GFSFRSRSAW
130 140 150 160 170 180
QERGGDDCGR GSRRRRRGAA GGGSSRAPPA GGGGGPAAAG GAEVRPRSVE LGLDERRGRG
190 200 210 220 230 240
RAEPEPEAEA GAPGGDRGAR DGDGPAGPGA CCRALLQIFR SKKFPSDKLE RLYQRYFFRL
250 260 270 280 290 300
NQSSLTMLMA VLVLVCLVML AFHAARPPLR LPHLAVLAAA VGVILVMAVL CNRAAFHQDH
310 320 330 340 350 360
MGLACYALIA VVLAVQVVGL LLPQPRSASE GIWWTVFFIY TIYTLLPVRM RAAVLSGVLL
370 380 390 400 410 420
SALHLAIALR ANAQDRFLLK QLVSNVLIFS CTNIVGVCTH YPAEVSQRQA FQETRECIQA
430 440 450 460 470 480
RLHSQRENQQ QERLLLSVLP RHVAMEMKAD INAKQEDMMF HKIYIQKHDN VSILFADIEG
490 500 510 520 530 540
FTSLASQCTA QELVMTLNEL FARFDKLAAE NHCLRIKILG DCYYCVSGLP EARADHAHCC
550 560 570 580 590 600
VEMGMDMIEA ISLVREVTGV NVNMRVGIHS GRVHCGVLGL RKWQFDVWSN DVTLANHMEA
610 620 630 640 650 660
GGKAGRIHIT KATLSYLNGD YEVEPGCGGE RNAYLKEHSI ETFLILRCTQ KRKEEKAMIA
670 680 690 700 710 720
KMNRQRTNSI GHNPPHWGAE RPFYNHLGGN QVSKEMKRMG FEDPKDKNAQ ESANPEDEVD
730 740 750 760 770 780
EFLGRAIDAR SIDRLRSEHV RKFLLTFREP DLEKKYSKQV DDRFGAYVAC ASLVFLFICF
790 800 810 820 830 840
VQITIVPHSV FMLSFYLTCF LLLTLVVFVS VIYSCVKLFP GPLQSLSRKI VRSKTNSTLV
850 860 870 880 890 900
GVFTITLVFL SAFVNMFMCN SEDLLGCLAD EHNISTSRVN ACHVAASAAN LSLGDEQGFC
910 920 930 940 950 960
GTPWPSCNFP EYFTYSVLLS LLACSVFLQI SCIGKLVLML AIELIYVLVV EVPRVTLFDN
970 980 990 1000 1010 1020
ADLLVTANAI DFNNNNGTSQ CPEHATKVAL KVVTPIIISV FVLALYLHAQ QVESTARLDF
1030 1040 1050 1060 1070 1080
LWKLQATEEK EEMEELQAYN RRLLHNILPK DVAAHFLARE RRNDELYYQS CECVAVMFAS
1090 1100 1110 1120 1130 1140
IANFSEFYVE LEANNEGVEC LRVLNEIIAD FDEIISEDRF RQLEKIKTIG STYMAASGLN
1150 1160 1170 1180 1190 1200
DSTYDKVGKT HIKALADFAM KLMDQMKYIN EHSFNNFQMK IGLNIGPVVA GVIGARKPQY
1210 1220 1230 1240 1250 1260
DIWGNTVNVA SRMDSTGVPD RIQVTTDMYQ VLAANTYQLE CRGVVKVKGK GEMMTYFLNG
GPPLS
|
P30803 in FASTA format |
|
ExPASy Home page
APAF Australia
