NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=PST-I;
PubMed=1649572 [NCBI, ExPASy, EBI, Israel, Japan]
Vliegenthart J.S., Ketelaar-Van Gaalen P.A.G., van de Klundert J.A.M.;
"Nucleotide sequence of the aacC3 gene, a gentamicin resistance determinant encoding aminoglycoside-(3)-N-acetyltransferase III expressed in Pseudomonas aeruginosa but not in Escherichia coli.";
Antimicrob. Agents Chemother. 35:892-897(1991).

Comments

FUNCTION: Catalyzes the synthesis of activated sulfate.
CATALYTIC ACTIVITY: ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate.
PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3 .
SIMILARITY: Belongs to the APS kinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X55652; CAA39183.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S18729; S18729.

3D structure databases

HSSP

Q12657; 1M7G. [HSSP ENTRY / PDB]

ModBase

P29811.

Ontologies

GO:0004020;	Molecular function: adenylylsulfate kinase activity (inferred from electronic annotation from HAMAP).
GO:0005524;	Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0000103;	Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00065; -; 1.
PBIL [Tree]

InterPro

IPR002891; APS_kinase_C.
Graphical view of domain structure.

Pfam

PF01583; APS_kinase; 1.
Pfam graphical view of domain structure.

ProDom

PD002350; APS_kinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGR00455; apsK; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

ATP-binding; Kinase; Nucleotide-binding; Phosphoprotein; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 214`	`214`	`Probable adenylyl-sulfate kinase.`	`PRO_0000105914`
`NP_BIND`	`13 20`	`8`	`ATP (Potential).`
`ACT_SITE`	`87 87`		`Phosphoserine intermediate (By similarity).`

Sequence information

Length: 214 AA [This is the length of the unprocessed precursor]

Molecular weight: 23922 Da [This is the MW of the unprocessed precursor]

CRC64: B0C207AC0DE9949E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIEHPGFVLW FTGLSGAGKT TIAVALENQL RARGIRIERL DGDTVRQSLT KDLGFSKEDR 

        70         80         90        100        110        120 
DKNIERVTFV AKLLSRNNVA VLSSFISPYA ATRDHVRGET TNFIEVFVDA PLETCIERDV 

       130        140        150        160        170        180 
KGMYKKAIAG EIPNFTGISD PYEAPANPDI HVKTHEQTLE ESVQTIIRRS SHGWNRTNTF 

       190        200        210 
PLKSRPNPPH RHKSKSSRAG EPFISPVFVL SIIA

P29811 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools