[1]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=1378832 [NCBI, ExPASy, EBI, Israel, Japan]
Janssens S.P.,
Shimouchi A.,
Quertermous T.,
Bloch D.B.,
Bloch K.D.;
"Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.";
J. Biol. Chem. 267:14519-14522(1992).
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[2]
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ERRATUM.
Janssens S.P.,
Shimouchi A.,
Quertermous T.,
Bloch D.B.,
Bloch K.D.;
J. Biol. Chem. 267:22694-22694(1992).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1016/0014-5793(92)80697-F; PubMed=1379542 [NCBI, ExPASy, EBI, Israel, Japan]
Marsden P.A.,
Schappert K.T.,
Chen H.S.,
Flowers M.,
Sundell C.L.,
Wilcox J.N.,
Lamas S.,
Michel T.;
"Molecular cloning and characterization of human endothelial nitric oxide synthase.";
FEBS Lett. 307:287-293(1992).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=7688726 [NCBI, ExPASy, EBI, Israel, Japan]
Marsden P.A.,
Heng H.H.Q.,
Scherer S.W.,
Stewart R.J.,
Hall A.V.,
Shi X.-M.,
Tsui L.-C.,
Schappert K.T.;
"Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.";
J. Biol. Chem. 268:17478-17488(1993).
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[5]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
TISSUE=Umbilical vein;
Liao J.K.;
Submitted (DEC-1993) to the EMBL/GenBank/DDBJ databases.
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[6]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
TISSUE=Placenta;
DOI=10.1006/bbrc.1994.1146; PubMed=7509596 [NCBI, ExPASy, EBI, Israel, Japan]
Nadaud S.A.,
Bonnardeaux A.,
Lathrop M.,
Soubrier F.;
"Gene structure, polymorphism and mapping of the human endothelial nitric oxide synthase gene.";
Biochem. Biophys. Res. Commun. 198:1027-1033(1994).
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[7]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=7519987 [NCBI, ExPASy, EBI, Israel, Japan]
Miyahara K.,
Kawamoto T.,
Sase K.,
Yui Y.,
Toda K.,
Yang L.X.,
Hattori R.,
Aoyama T.,
Yamamoto Y.,
Doi Y.,
Ogoshi S.,
Hashimoto K.,
Kawai C.,
Sasayama S.,
Shizuta Y.;
"Cloning and structural characterization of the human endothelial nitric-oxide-synthase gene.";
Eur. J. Biochem. 223:719-726(1994).
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[8]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS GLN-112; ASP-298; MET-827; MET-885 AND LEU-982.
SeattleSNPs program for genomic applications;
Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
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[9]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[10]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-53.
TISSUE=Placenta;
DOI=10.1006/geno.1994.1068; PubMed=7514568 [NCBI, ExPASy, EBI, Israel, Japan]
Robinson L.J.,
Weremowicz S.,
Morton C.C.,
Michel T.;
"Isolation and chromosomal localization of the human endothelial nitric oxide synthase (NOS3) gene.";
Genomics 19:350-357(1994).
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[11]
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NUCLEOTIDE SEQUENCE [MRNA] OF 411-528.
TISSUE=Platelet;
DOI=10.1016/0024-3205(95)02191-K; PubMed=7475956 [NCBI, ExPASy, EBI, Israel, Japan]
Sase K.,
Michel T.;
"Expression of constitutive endothelial nitric oxide synthase in human blood platelets.";
Life Sci. 57:2049-2055(1995).
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[12]
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PROTEIN SEQUENCE OF 167-175; 531-540; 835-845; 876-881; 886-898; 1001-1005 AND 1068-1080, AND TISSUE SPECIFICITY.
TISSUE=Placenta;
DOI=10.1006/abbi.1994.1232; PubMed=7515611 [NCBI, ExPASy, EBI, Israel, Japan]
Garvey E.P.,
Tuttle J.V.,
Covington K.,
Merrill B.M.,
Wood E.R.,
Baylis S.A.,
Charles I.G.;
"Purification and characterization of the constitutive nitric oxide synthase from human placenta.";
Arch. Biochem. Biophys. 311:235-241(1994).
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[13]
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INTERACTION WITH NOSIP, ENZYME REGULATION, AND SUBCELLULAR LOCATION.
DOI=10.1096/fj.00-0078com; PubMed=11149895 [NCBI, ExPASy, EBI, Israel, Japan]
Dedio J.,
Koenig P.,
Wohlfart P.,
Schroeder C.,
Kummer W.,
Mueller-Esterl W.;
"NOSIP, a novel modulator of endothelial nitric oxide synthase activity.";
FASEB J. 15:79-89(2001).
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[14]
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INTERACTION WITH NOSTRIN, ENZYME REGULATION, AND SUBCELLULAR LOCATION.
DOI=10.1073/pnas.252345399; PubMed=12446846 [NCBI, ExPASy, EBI, Israel, Japan]
Zimmermann K.,
Opitz N.,
Dedio J.,
Renne C.,
Mueller-Esterl W.,
Oess S.;
"NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase.";
Proc. Natl. Acad. Sci. U.S.A. 99:17167-17172(2002).
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[15]
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SUBCELLULAR LOCATION.
DOI=10.1242/jcs.02620; PubMed=16234328 [NCBI, ExPASy, EBI, Israel, Japan]
Icking A.,
Matt S.,
Opitz N.,
Wiesenthal A.,
Mueller-Esterl W.,
Schilling K.;
"NOSTRIN functions as a homotrimeric adaptor protein facilitating internalization of eNOS.";
J. Cell Sci. 118:5059-5069(2005).
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[16]
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SUBCELLULAR LOCATION.
DOI=10.1128/MCB.25.18.8251-8258.2005; PubMed=16135813 [NCBI, ExPASy, EBI, Israel, Japan]
Schleicher M.,
Brundin F.,
Gross S.,
Mueller-Esterl W.,
Oess S.;
"Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton.";
Mol. Cell. Biol. 25:8251-8258(2005).
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[17]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-81, AND MASS SPECTROMETRY.
DOI=10.1016/j.cell.2007.11.025; PubMed=18083107 [NCBI, ExPASy, EBI, Israel, Japan]
Rikova K.,
Guo A.,
Zeng Q.,
Possemato A.,
Yu J.,
Haack H.,
Nardone J.,
Lee K.,
Reeves C.,
Li Y.,
Hu Y.,
Tan Z.,
Stokes M.,
Sullivan L.,
Mitchell J.,
Wetzel R.,
Macneill J.,
Ren J.M.,
Yuan J., ![]()
Bakalarski C.E.,
Villen J.,
Kornhauser J.M.,
Smith B.,
Li D.,
Zhou X.,
Gygi S.P.,
Gu T.-L.,
Polakiewicz R.D.,
Rush J.,
Comb M.J.;
"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.";
Cell 131:1190-1203(2007).
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[18]
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X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS).
DOI=10.1038/6675; PubMed=10074942 [NCBI, ExPASy, EBI, Israel, Japan]
Fischmann T.O.,
Hruza A.,
Niu X.D.,
Fossetta J.D.,
Lunn C.A.,
Dolphin E.,
Prongay A.J.,
Reichert P.,
Lundell D.J.,
Narula S.K.,
Weber P.C.;
"Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation.";
Nat. Struct. Biol. 6:233-242(1999).
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[19]
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X-RAY CRYSTALLOGRAPHY (1.96 ANGSTROMS) OF 67-480.
DOI=10.1021/bi026313j; PubMed=12437348 [NCBI, ExPASy, EBI, Israel, Japan]
Rosenfeld R.J.,
Garcin E.D.,
Panda K.,
Andersson G.,
Aberg A.,
Wallace A.V.,
Morris G.M.,
Olson A.J.,
Stuehr D.J.,
Tainer J.A.,
Getzoff E.D.;
"Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.";
Biochemistry 41:13915-13925(2002).
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[20]
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VARIANT SUSCEPTIBILITY TO CORONARY SPASM ASP-298.
DOI=10.1007/s004390050785; PubMed=9737779 [NCBI, ExPASy, EBI, Israel, Japan]
Yoshimura M.,
Yasue H.,
Nakayama M.,
Shimasaki Y.,
Sumida H.,
Sugiyama S.,
Kugiyama K.,
Ogawa H.,
Ogawa Y.,
Saito Y.,
Miyamoto Y.,
Nakao K.;
"A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm in the Japanese.";
Hum. Genet. 103:65-69(1998).
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[21]
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VARIANT SUSCEPTIBILITY TO CORONARY SPASM ASP-298.
DOI=10.1097/00008571-200112000-00009; PubMed=11740345 [NCBI, ExPASy, EBI, Israel, Japan]
Sofowora G.,
Dishy V.,
Xie H.G.,
Imamura H.,
Nishimi Y.,
Morales C.R.,
Morrow J.D.,
Kim R.B.,
Stein C.M.,
Wood A.J.;
"In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism.";
Pharmacogenetics 11:809-814(2001).
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[22]
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VARIANTS [LARGE SCALE ANALYSIS] CYS-474 AND GLN-602.
DOI=10.1126/science.1133427; PubMed=16959974 [NCBI, ExPASy, EBI, Israel, Japan]
Sjoeblom T.,
Jones S.,
Wood L.D.,
Parsons D.W.,
Lin J.,
Barber T.D.,
Mandelker D.,
Leary R.J.,
Ptak J.,
Silliman N.,
Szabo S.,
Buckhaults P.,
Farrell C.,
Meeh P.,
Markowitz S.D.,
Willis J.,
Dawson D.,
Willson J.K.V.,
Gazdar A.F., ![]()
Hartigan J.,
Wu L.,
Liu C.,
Parmigiani G.,
Park B.H.,
Bachman K.E.,
Papadopoulos N.,
Vogelstein B.,
Kinzler K.W.,
Velculescu V.E.;
"The consensus coding sequences of human breast and colorectal cancers.";
Science 314:268-274(2006).
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