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UniProtKB/Swiss-Prot entry P29443

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name XYLA_LACBR
Primary accession number P29443
Secondary accession numbers None
Integrated into Swiss-Prot on April 1, 1993
Sequence was last modified on April 1, 1993 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 52)
Name and origin of the protein
Protein name Xylose isomerase
Synonym EC 5.3.1.5
Gene name
Name: xylA
From
Lactobacillus brevis [TaxID: 1580] 
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0378-1119(92)90718-5; PubMed=1587475 [NCBI, ExPASy, EBI, Israel, Japan]
Bor Y.-C., Moraes C., Lee S.-P., Crosby W.L., Sinskey A.J., Batt C.A.;
"Cloning and sequencing the Lactobacillus brevis gene encoding xylose isomerase.";
Gene 114:127-131(1992).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Bor Y.-C., Batt C.A.;
Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M84564; AAA25256.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF045552; AAC95125.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR JC1137; JC1137.
3D structure databases
HSSP P19148; 1A0C. [HSSP ENTRY / PDB]
ModBase P29443.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from HAMAP).
GO:0009045; Molecular function: xylose isomerase activity (inferred from electronic annotation from HAMAP).
GO:0042732; Biological process: D-xylose metabolic process (inferred from electronic annotation from HAMAP).
GO:0006098; Biological process: pentose-phosphate shunt (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00455; -; 1.
PBIL [Tree]
InterPro IPR013022; Xyl_isomerase-like_TIM-brl.
IPR012307; Xyl_isomerase-typ_TIM-brl.
IPR001998; Xylose_isom.
IPR013452; Xylose_isom_bac.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.150; Xyl_isomerase-like_TIM-brl; 1.
Pfam PF01261; AP_endonuc_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00688; XYLOSISMRASE.
TIGRFAMs TIGR02630; xylose_isom_A; 1.
PROSITE PS00172; XYLOSE_ISOMERASE_1; 1.
PS00173; XYLOSE_ISOMERASE_2; 1.
Other
ProtoNet P29443.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Cytoplasm; Isomerase; Magnesium; Metal-binding; Pentose shunt; Xylose metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   449  449     Xylose isomerase. PRO_0000195781
ACT_SITE   103   103        By similarity. 
ACT_SITE   106   106        By similarity. 
METAL   234   234        Magnesium 1 (By similarity). 
METAL   270   270        Magnesium 1 (By similarity). 
METAL   270   270        Magnesium 2 (By similarity). 
METAL   273   273        Magnesium 2 (By similarity). 
METAL   298   298        Magnesium 1 (By similarity). 
METAL   309   309        Magnesium 2 (By similarity). 
METAL   311   311        Magnesium 2 (By similarity). 
METAL   342   342        Magnesium 1 (By similarity). 
Sequence information
Length: 449 AA [This is the length of the unprocessed precursor] Molecular weight: 50757 Da [This is the MW of the unprocessed precursor] CRC64: 37170CFB5C435E4E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTEEYWKGVD KIQYVGHQDK KSGLGFQYYN PEEEIMGKKM KDWLRFAVAY WHTFDQRLVD 

        70         80         90        100        110        120 
PFGDGTAQRP YDKYTDPMDL ALAKVDAAFE FYQKLGVDYL CFHDRDLAPE GDTLRETNAN 

       130        140        150        160        170        180 
LDKVVDKIVE YQKTSGMKVL WNTSNMFTNP RFVEGAATSP YADVFAYSAA QLKHSLEIGK 

       190        200        210        220        230        240 
RVGSENYVFW GGREGYESLW NTNMKQEQEH AAKIFHMAKD YANEIGFDAQ MLLEPKPKEP 

       250        260        270        280        290        300 
TTHQYDFDAA TTIAFMKEYD LDKDFKLNLE GNHANLAGHT YQHEIRVARE AGLLGSLDAN 

       310        320        330        340        350        360 
QGDKLIGWDI DEYPSNLYET TAAMYEVVEN GSIGPRGGLN FDAKPRRSAF APEDLFLGHI 

       370        380        390        400        410        420 
VGMDSFAAGL RVAAAMKQDG FLDNLKADRY SSYKSGVGAD IESGKADLKS LEAYAIDKPQ 

       430        440 
SELIAATHSD HLEEIKDTIN HYIIDTLSK
P29443 in FASTA format

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