ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P29072


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name CHEA_BACSU
Primary accession number P29072
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 1992
Sequence was last modified on December 1, 1992 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 73)
Name and origin of the protein
Protein name Chemotaxis protein cheA
Synonym EC 2.7.13.3
Gene name
Name: cheA
Synonyms: cheN
OrderedLocusNames: BSU16430
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=1938941 [NCBI, ExPASy, EBI, Israel, Japan]
Fuhrer D.K., Ordal G.W.;
"Bacillus subtilis CheN, a homolog of CheA, the central regulator of chemotaxis in Escherichia coli.";
J. Bacteriol. 173:7443-7448(1991).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M57894; AAA22313.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99112; CAB13516.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A41653; QRBSCN.
RefSeq NP_389525.1; -.
3D structure databases
HSSP Q56310; 1I59. [HSSP ENTRY / PDB]
ModBase P29072.
Enzyme and pathway databases
BioCyc BSUB224308:BSU1644-MON; -.
Organism-specific databases
SubtiList BG10256; cheA. [Micado]
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0016020; Cellular component: membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0000155; Molecular function: two-component sensor activity (inferred from electronic annotation from InterPro).
GO:0006928; Biological process: cell motion (inferred from electronic annotation from InterPro).
GO:0006935; Biological process: chemotaxis (inferred from electronic annotation from InterPro).
GO:0018106; Biological process: peptidyl-histidine phosphorylation (inferred from electronic annotation from InterPro).
GO:0000160; Biological process: two-component signal transduction system (phosphorelay) (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR003594; ATP_bd_ATPase.
IPR002545; CheW.
IPR004358; Sig_transdc_His_kin-like_C.
IPR008207; Sig_transdc_His_kin_P-trf.
IPR004105; Sig_transdc_His_kin_subgr_dim.
IPR005467; Sig_transdc_His_kinase_core.
IPR010808; Sig_transdc_His_kinase_P2-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.30.565.10; ATP_bd_ATPase; 1.
Pfam PF01584; CheW; 1.
PF02895; H-kinase_dim; 1.
PF02518; HATPase_c; 1.
PF01627; Hpt; 1.
PF07194; P2; 1.
Pfam graphical view of domain structure.
PRINTS PR00344; BCTRLSENSOR.
ProDom PD003142; Hpt_N; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00260; CheW; 1.
SM00387; HATPase_c; 1.
SM00073; HPT; 1.
SMART graphical view of domain structure.
PROSITE PS50851; CHEW; 1.
PS50109; HIS_KIN; 1.
PS50894; HPT; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P29072.
ProtoNet P29072.
Genome annotation databases
GeneID 939600; -.
GenomeReviews AL009126_GR; BSU16430.
KEGG bsu:BSU16430; -.
NMPDR fig|224308.1.peg.1646; -.
Phylogenomic databases
HOGENOM P29072; -.
Genome annotation databases
CMR P29072; BSU16430.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chemotaxis; Complete proteome; Kinase; Membrane; Phosphoprotein; Transferase; Two-component regulatory system.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   671  671     Chemotaxis protein cheA. PRO_0000074711
DOMAIN   1   103  103     HPt. 
DOMAIN   290   539  250     Histidine kinase. 
DOMAIN   541   671  131     CheW-like. 
MOD_RES   46    46        Phosphohistidine; by autocatalysis (By similarity). 
Sequence information
Length: 671 AA [This is the length of the unprocessed precursor] Molecular weight: 74768 Da [This is the MW of the unprocessed precursor] CRC64: 289E0B8FFEFD4E91 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDMNQYLDVF IDESKEHLQT CNEKLLLLEK DPTDLQLVHD IFRAAHTLKG MSATMGYTDL 

        70         80         90        100        110        120 
AHLTHLLENV LDAIRNGDME VTSDWLDILF EALDHLETMV QSIIDGGDGK RDISEVSAKL 

       130        140        150        160        170        180 
DVNGAHAESA ASAEPAEAQS SASDWEYDEF ERTVIQEAEE QGFKRYEIKI SLNENCMLKA 

       190        200        210        220        230        240 
VRVYMVFEKL NEVGEVAKTI PSAEVLETED FGTDFQVCFL THQSAEDIEQ LINGVSEIEH 

       250        260        270        280        290        300 
VEVIQGAPLT SAEKPEESKQ EDSPAAAVPA NEEKQKQPAK NDEQAKHSAG GSKTIRVNID 

       310        320        330        340        350        360 
RLDSLMNLFE ELVIDRGRLE QIAKELEHNE LTETVERMTR ISGDLQSIIL NMRMVPVETV 

       370        380        390        400        410        420 
FNRFPRMIRQ LQKELNKKIE LSIIGAETEL DRTVIDEIGD PLVHLIRNSI DHGIEAPETR 

       430        440        450        460        470        480 
LQKGKPESGK VVLKAYHSGN HVFIEVEDDG AGLNRKKILE KPLERVITEK EAETLEDNQI 

       490        500        510        520        530        540 
YELIFAPGFS TADQISDISG RGVGLDVVKN KLESLGGSVS VKSAEGQGSL FSIQLPLTLS 

       550        560        570        580        590        600 
IISVLLIKLE EETFAIPISS IIETAVIDRK DILQTHDREV IDFRGHIVPV VYLKEEFKIE 

       610        620        630        640        650        660 
DTRKDAEQLH IIVVKKGDKP TAFVVDSFIG QQEVVLKSLG DYLTNVFAIS GATILGDGEV 

       670 
ALIIDCNALI I 

P29072 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by au flag APAF Australia Mirror sites: Brazil  Canada  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!