[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 21-40. STRAIN=RS12; PubMed=8081499 [NCBI, ExPASy, EBI, Israel, Japan] Thaller M.C., Berlutti F., Schippa S., Lombardi G., Rossolini G.M.; "Characterization and sequence of PhoC, the principal phosphate-irrepressible acid phosphatase of Morganella morganii."; Microbiology 140:1341-1350(1994).
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=ATCC 8019 / CCM 680 / DSM 30117 / NCIMB 10466; DOI=10.1128/AEM.66.7.2811-2816.2000; PubMed=10877772 [NCBI, ExPASy, EBI, Israel, Japan] Mihara Y., Utagawa T., Yamada H., Asano Y.; "Phosphorylation of nucleosides by the mutated acid phosphatase from Morganella morganii."; Appl. Environ. Microbiol. 66:2811-2816(2000).

Comments

CATALYTIC ACTIVITY: A phosphate monoester + H₂O = an alcohol + phosphate.
BIOPHYSICOCHEMICAL PROPERTIES:

pH dependence: Optimum pH is about 6;
SUBUNIT: Homotetramer.
SUBCELLULAR LOCATION: Periplasm.
SIMILARITY: Belongs to the class A bacterial acid phosphatase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X64444; CAA45774.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AB035805; BAA96744.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S19187; S19187.

3D structure databases

HSSP

Q9S1A6; 1D2T. [HSSP ENTRY / PDB]

SMR

P28581; 25-245.

ModBase

P28581.

Ontologies

GO:0016020;	Cellular component: membrane (inferred from electronic annotation from InterPro).
GO:0030288;	Cellular component: outer membrane-bounded periplasmic space (inferred from electronic annotation from InterPro).
GO:0003993;	Molecular function: acid phosphatase activity (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR011158; Acid_Pase_ClassA.
IPR001011; Acid_Pase_classA_bac.
IPR016118; P_Acid_Pase/Cl_peroxidase_N.
IPR000326; P_Acid_Pase_2/haloperoxidase.
Graphical view of domain structure.

Gene3D

G3DSA:1.20.144.10; P_Acid_Pase/Cl_peroxidase_N; 1.

Pfam

PF01569; PAP2; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000897; Acid_Ptase_ClsA; 1.

PRINTS

PR00483; BACPHPHTASE.

ProDom

PD009838; Bac_AcPataseA; 1.
[Domain structure / List of seq. sharing at least 1 domain]

SMART

SM00014; acidPPc; 1.
SMART graphical view of domain structure.

PROSITE

PS01157; ACID_PHOSPH_CL_A; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; Hydrolase; Periplasm; Signal.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 20`	`20`
`CHAIN`	`21 249`	`229`	`Major phosphate-irrepressible acid phosphatase.`	`PRO_0000023999`

Sequence information

Length: 249 AA [This is the length of the unprocessed precursor]

Molecular weight: 26999 Da [This is the MW of the unprocessed precursor]

CRC64: C43F3698052B6A5C [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKKNIIAGCL FSLFSLSALA AIPAGNDATT KPDLYYLKNE QAIDSLKLLP PPPEVGSIQF 

        70         80         90        100        110        120 
LNDQAMYEKG RMLRNTERGK QAQADADLAA GGVATAFSGA FGYPITEKDS PELYKLLTNM 

       130        140        150        160        170        180 
IEDAGDLATR SAKEHYMRIR PFAFYGTETC NTKDQKKLST NGSYPSGHTS IGWATALVLA 

       190        200        210        220        230        240 
EVNPANQDAI LERGYQLGQS RVICGYHWQS DVDAARIVGS AAVATLHSDP AFQAQLAKAK 


QEFAQKSQK

P28581 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools