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UniProtKB/Swiss-Prot entry P28032

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ADH2_SOLLC
Primary accession number P28032
Secondary accession numbers None
Integrated into Swiss-Prot on August 1, 1992
Sequence was last modified on July 1, 1993 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 62)
Name and origin of the protein
Protein name Alcohol dehydrogenase 2
Synonym EC 1.1.1.1
Gene name
Name: ADH2
From
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE.
DOI=10.1016/0378-1119(93)90119-N; PubMed=8428654 [NCBI, ExPASy, EBI, Israel, Japan]
Genez A.L., Staraci L.C., Alexander D.C., Rejda V.M., Williamson V.M., Chase T. Jr., Williams B.G.;
"Isolation of a tomato alcohol dehydrogenase 2-encoding cDNA using phage-promoted antibody screening of a plasmid cDNA library.";
Gene 123:157-164(1993).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
STRAIN=cv. De Ruiter 83G38;
DOI=10.1007/BF00040690; PubMed=7811967 [NCBI, ExPASy, EBI, Israel, Japan]
Longhurst T., Lee E., Hinde R., Brady C., Speirs J.;
"Structure of the tomato Adh2 gene and Adh2 pseudogenes, and a study of Adh2 gene expression in fruit.";
Plant Mol. Biol. 26:1073-1084(1994).
[3]
 NUCLEOTIDE SEQUENCE [MRNA] OF 252-380.
STRAIN=cv. Orlando;
DOI=10.1016/0014-5793(91)81379-M; PubMed=1765164 [NCBI, ExPASy, EBI, Israel, Japan]
van der Straeten D., Pousada R.A.R., Gielen J., van Montagu M.;
"Tomato alcohol dehydrogenase. Expression during fruit ripening and under hypoxic conditions.";
FEBS Lett. 295:39-42(1991).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M86724; AAA34133.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X77233; CAA54450.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X60600; CAA43055.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S51826; S51826.
UniGene Les.19427
3D structure databases
HSSP P11766; 1M6H. [HSSP ENTRY / PDB]
ModBase P28032.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004022; Molecular function: alcohol dehydrogenase activity (inferred from electronic annotation from EC).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR013154; AlcDHase_GroES-like.
IPR002085; AlcDHase_SF_Zn.
IPR013149; AlcDHase_Zn-bd.
IPR002328; AlcDHase_Zn_CS.
Graphical view of domain structure.
PANTHER PTHR11695; ADH_Sf_Zn; 1.
Pfam PF08240; ADH_N; 1.
PF00107; ADH_zinc_N; 1.
Pfam graphical view of domain structure.
PROSITE PS00059; ADH_ZINC; 1.
BLOCKS P28032.
ProtoNet P28032.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; Metal-binding; NAD; Oxidoreductase; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   380  380     Alcohol dehydrogenase 2. PRO_0000160702
METAL   48    48        Zinc 1; catalytic (By similarity). 
METAL   70    70        Zinc 1; catalytic (By similarity). 
METAL   100   100        Zinc 2 (By similarity). 
METAL   103   103        Zinc 2 (By similarity). 
METAL   106   106        Zinc 2 (By similarity). 
METAL   114   114        Zinc 2 (By similarity). 
METAL   178   178        Zinc 1; catalytic (By similarity). 
Sequence information
Length: 380 AA [This is the length of the unprocessed precursor] Molecular weight: 41040 Da [This is the MW of the unprocessed precursor] CRC64: D5B123DF9DE28027 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSTTVGQVIR CKAAVAWEAG KPLVMEEVDV APPQKMEVRL KILYTSLCHT DVYFWEAKGQ 

        70         80         90        100        110        120 
NPVFPRILGH EAAGIVESVG EGVTDLAPGD HVLPVFTGEC KDCAHCKSEE SNMCSLLRIN 

       130        140        150        160        170        180 
TDRGVMLNDG KSRFSINGNP IYHFVGTSTF SEYTVVHVGC VAKINPLAPL DKVCVLSCGI 

       190        200        210        220        230        240 
STGLGASLNV AKPTKGSSVA IFGLGAVGLA AAEGARIAGA SRIIGVDLNA SRFEQAKKFG 

       250        260        270        280        290        300 
VTEFVNPKDY SKPVQEVIAE MTDGGVDRSV ECTGHIDAMI SAFECVHDGW GVAVLVGVPH 

       310        320        330        340        350        360 
KEAVFKTHPL NFLNERTLKG TFFGNYKPRS DIPCVVEKYM NKELELEKFI THTLPFAEIN 

       370        380 
KAFDLMLKGE GLRCIITMAD
P28032 in FASTA format

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