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UniProtKB/Swiss-Prot entry P26208

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BGLA_CLOTH
Primary accession number P26208
Secondary accession number A3DBX4
Integrated into Swiss-Prot on May 1, 1992
Sequence was last modified on May 1, 1992 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 57)
Name and origin of the protein
Protein name Beta-glucosidase A
Synonyms EC 3.2.1.21
Gentiobiase
Cellobiase
Beta-D-glucoside glucohydrolase
Gene name
Name: bglA
OrderedLocusNames: Cthe_0212
From
Clostridium thermocellum (strain ATCC 27405 / DSM 1237) [TaxID: 203119] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1111/j.1432-1033.1991.tb16186.x; PubMed=1909624 [NCBI, ExPASy, EBI, Israel, Japan]
Graebnitz F., Seiss M., Ruecknagel K.P., Staudenbauer W.L.;
"Structure of the beta-glucosidase gene bglA of Clostridium thermocellum. Sequence analysis reveals a superfamily of cellulases and beta-glycosidases including human lactase/phlorizin hydrolase.";
Eur. J. Biochem. 200:301-309(1991).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D., Newcomb M., Richardson P.;
"Complete sequence of Clostridium thermocellum ATCC 27405.";
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X60268; CAA42814.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CP000568; ABN51453.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S17215; S17215.
RefSeq YP_001036646.1; -.
3D structure databases
HSSP Q08638; 1OD0. [HSSP ENTRY / PDB]
ModBase P26208.
Ontologies
GO
GO:0008422; Molecular function: beta-glucosidase activity (inferred from electronic annotation from EC).
GO:0043169; Molecular function: cation binding (inferred from electronic annotation from InterPro).
GO:0030245; Biological process: cellulose catabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001360; Glyco_hydro_1.
IPR017736; Glyco_hydro_1_beta-glucosidase.
IPR013781; Glyco_hydro_sub_cat.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.80; Glyco_hydro_cat; 1.
PANTHER PTHR10353; Glyco_hydro_1; 1.
Pfam PF00232; Glyco_hydro_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00131; GLHYDRLASE1.
PROSITE PS00572; GLYCOSYL_HYDROL_F1_1; 1.
PS00653; GLYCOSYL_HYDROL_F1_2; 1.
BLOCKS P26208.
ProtoNet P26208.
Genome annotation databases
GeneID 4808630; -.
GenomeReviews CP000568_GR; Cthe_0212.
KEGG cth:Cthe_0212; -.
NMPDR fig|203119.1.peg.2308; -.
Other
LinkHub P26208; -.
Genome annotation databases
CMR P26208; Cthe_0212.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Cellulose degradation; Complete proteome; Glycosidase; Hydrolase; Polysaccharide degradation.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   448  448     Beta-glucosidase A. PRO_0000063876
ACT_SITE   166   166        Proton donor (Potential). 
ACT_SITE   355   355        Nucleophile (By similarity). 
Sequence information
Length: 448 AA [This is the length of the unprocessed precursor] Molecular weight: 51482 Da [This is the MW of the unprocessed precursor] CRC64: D59B9EB7BEE67621 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSKITFPKDF IWGSATAAYQ IEGAYNEDGK GESIWDRFSH TPGNIADGHT GDVACDHYHR 

        70         80         90        100        110        120 
YEEDIKIMKE IGIKSYRFSI SWPRIFPEGT GKLNQKGLDF YKRLTNLLLE NGIMPAITLY 

       130        140        150        160        170        180 
HWDLPQKLQD KGGWKNRDTT DYFTEYSEVI FKNLGDIVPI WFTHNEPGVV SLLGHFLGIH 

       190        200        210        220        230        240 
APGIKDLRTS LEVSHNLLLS HGKAVKLFRE MNIDAQIGIA LNLSYHYPAS EKAEDIEAAE 

       250        260        270        280        290        300 
LSFSLAGRWY LDPVLKGRYP ENALKLYKKK GIELSFPEDD LKLISQPIDF IAFNNYSSEF 

       310        320        330        340        350        360 
IKYDPSSESG FSPANSILEK FEKTDMGWII YPEGLYDLLM LLDRDYGKPN IVISENGAAF 

       370        380        390        400        410        420 
KDEIGSNGKI EDTKRIQYLK DYLTQAHRAI QDGVNLKAYY LWSLLDNFEW AYGYNKRFGI 

       430        440 
VHVNFDTLER KIKDSGYWYK EVIKNNGF
P26208 in FASTA format

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