[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1083/jcb.114.3.443; PubMed=1860879 [NCBI, ExPASy, EBI, Israel, Japan]
Froehlich K.-U.,
Fries H.W.,
Ruediger M.,
Erdmann R.,
Botstein D.,
Mecke D.;
"Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression.";
J. Cell Biol. 114:443-453(1991).
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[2]
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SEQUENCE REVISION.
Froehlich K.-U.;
Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases.
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204508 / S288c;
PubMed=9169867 [NCBI, ExPASy, EBI, Israel, Japan]
Jacq C.,
Alt-Moerbe J.,
Andre B.,
Arnold W.,
Bahr A.,
Ballesta J.P.G.,
Bargues M.,
Baron L.,
Becker A.,
Biteau N.,
Bloecker H.,
Blugeon C.,
Boskovic J.,
Brandt P.,
Brueckner M.,
Buitrago M.J.,
Coster F.,
Delaveau T.,
del Rey F., ![]()
Dujon B.,
Eide L.G.,
Garcia-Cantalejo J.M.,
Goffeau A.,
Gomez-Peris A.,
Granotier C.,
Hanemann V.,
Hankeln T.,
Hoheisel J.D.,
Jaeger W.,
Jimenez A.,
Jonniaux J.-L.,
Kraemer C.,
Kuester H.,
Laamanen P.,
Legros Y.,
Louis E.J.,
Moeller-Rieker S.,
Monnet A.,
Moro M.,
Mueller-Auer S.,
Nussbaumer B.,
Paricio N.,
Paulin L.,
Perea J.,
Perez-Alonso M.,
Perez-Ortin J.E.,
Pohl T.M.,
Prydz H.,
Purnelle B.,
Rasmussen S.W.,
Remacha M.A.,
Revuelta J.L.,
Rieger M.,
Salom D.,
Saluz H.P.,
Saiz J.E.,
Saren A.-M.,
Schaefer M.,
Scharfe M.,
Schmidt E.R.,
Schneider C.,
Scholler P.,
Schwarz S.,
Soler-Mira A.,
Urrestarazu L.A.,
Verhasselt P.,
Vissers S.,
Voet M.,
Volckaert G.,
Wagner G.,
Wambutt R.,
Wedler E.,
Wedler H.,
Woelfl S.,
Harris D.E.,
Bowman S.,
Brown D.,
Churcher C.M.,
Connor R.,
Dedman K.,
Gentles S.,
Hamlin N.,
Hunt S.,
Jones L.,
McDonald S.,
Murphy L.D.,
Niblett D.,
Odell C.,
Oliver K.,
Rajandream M.A.,
Richards C.,
Shore L.,
Walsh S.V.,
Barrell B.G.,
Dietrich F.S.,
Mulligan J.T.,
Allen E.,
Araujo R.,
Aviles E.,
Berno A.,
Carpenter J.,
Chen E.,
Cherry J.M.,
Chung E.,
Duncan M.,
Hunicke-Smith S.,
Hyman R.W.,
Komp C.,
Lashkari D.,
Lew H.,
Lin D.,
Mosedale D.,
Nakahara K.,
Namath A.,
Oefner P.,
Oh C.,
Petel F.X.,
Roberts D.,
Schramm S.,
Schroeder M.,
Shogren T.,
Shroff N.,
Winant A.,
Yelton M.A.,
Botstein D.,
Davis R.W.,
Johnston M.,
Andrews S.,
Brinkman R.,
Cooper J.,
Ding H.,
Du Z.,
Favello A.,
Fulton L.,
Gattung S.,
Greco T.,
Hallsworth K.,
Hawkins J.,
Hillier L.W.,
Jier M.,
Johnson D.,
Johnston L.,
Kirsten J.,
Kucaba T.,
Langston Y.,
Latreille P.,
Le T.,
Mardis E.,
Menezes S.,
Miller N.,
Nhan M.,
Pauley A.,
Peluso D.,
Rifkin L.,
Riles L.,
Taich A.,
Trevaskis E.,
Vignati D.,
Wilcox L.,
Wohldman P.,
Vaudin M.,
Wilson R.,
Waterston R.,
Albermann K.,
Hani J.,
Heumann K.,
Kleine K.,
Mewes H.-W.,
Zollner A.,
Zaccaria P.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.";
Nature 387:75-78(1997).
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[4]
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FUNCTION, INTERACTION WITH NPL4, AND SUBCELLULAR LOCATION.
DOI=10.1016/S0092-8674(01)00595-5; PubMed=11733065 [NCBI, ExPASy, EBI, Israel, Japan]
Rape M.,
Hoppe T.,
Gorr I.,
Kalocay M.,
Richly H.,
Jentsch S.;
"Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone.";
Cell 107:667-677(2001).
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[5]
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INTERACTION WITH NPL4.
PubMed=11598205 [NCBI, ExPASy, EBI, Israel, Japan]
Hitchcock A.L.,
Krebber H.,
Frietze S.,
Lin A.,
Latterich M.,
Silver P.A.;
"The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation.";
Mol. Biol. Cell 12:3226-3241(2001).
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[6]
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FUNCTION.
DOI=10.1038/ncb746; PubMed=11813000 [NCBI, ExPASy, EBI, Israel, Japan]
Jarosch E.,
Taxis C.,
Volkwein C.,
Bordallo J.,
Finley D.,
Wolf D.H.,
Sommer T.;
"Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.";
Nat. Cell Biol. 4:134-139(2002).
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[7]
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FUNCTION.
DOI=10.1038/414652a; PubMed=11740563 [NCBI, ExPASy, EBI, Israel, Japan]
Ye Y.,
Meyer H.H.,
Rapoport T.A.;
"The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.";
Nature 414:652-656(2001).
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[8]
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FUNCTION.
DOI=10.1093/emboj/21.4.615; PubMed=11847109 [NCBI, ExPASy, EBI, Israel, Japan]
Braun S.,
Matuschewski K.,
Rape M.,
Thoms S.,
Jentsch S.;
"Role of the ubiquitin-selective CDC48(UFD1/NPL4) chaperone (segregase) in ERAD of OLE1 and other substrates.";
EMBO J. 21:615-621(2002).
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[9]
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LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
DOI=10.1038/nature02046; PubMed=14562106 [NCBI, ExPASy, EBI, Israel, Japan]
Ghaemmaghami S.,
Huh W.-K.,
Bower K.,
Howson R.W.,
Belle A.,
Dephoure N.,
O'Shea E.K.,
Weissman J.S.;
"Global analysis of protein expression in yeast.";
Nature 425:737-741(2003).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-683, UBIQUITINATION AT LYS-594 AND LYS-673, AND MASS SPECTROMETRY.
DOI=10.1038/nbt849; PubMed=12872131 [NCBI, ExPASy, EBI, Israel, Japan]
Peng J.,
Schwartz D.,
Elias J.E.,
Thoreen C.C.,
Cheng D.,
Marsischky G.,
Roelofs J.,
Finley D.,
Gygi S.P.;
"A proteomics approach to understanding protein ubiquitination.";
Nat. Biotechnol. 21:921-926(2003).
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[11]
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INTERACTION WITH UBX PROTEINS.
DOI=10.1038/sj.embor.7400203; PubMed=15258615 [NCBI, ExPASy, EBI, Israel, Japan]
Schuberth C.,
Richly H.,
Rumpf S.,
Buchberger A.;
"Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation.";
EMBO Rep. 5:818-824(2004).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-519, AND MASS SPECTROMETRY.
DOI=10.1074/mcp.M400219-MCP200; PubMed=15665377 [NCBI, ExPASy, EBI, Israel, Japan]
Gruhler A.,
Olsen J.V.,
Mohammed S.,
Mortensen P.,
Faergeman N.J.,
Mann M.,
Jensen O.N.;
"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.";
Mol. Cell. Proteomics 4:310-327(2005).
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[13]
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INTERACTION WITH OTU1; UFD2 AND DOA1.
DOI=10.1016/j.molcel.2005.12.014; PubMed=16427015 [NCBI, ExPASy, EBI, Israel, Japan]
Rumpf S.,
Jentsch S.;
"Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone.";
Mol. Cell 21:261-269(2006).
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[14]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-519 AND SER-770, AND MASS SPECTROMETRY.
DOI=10.1021/pr060559j; PubMed=17330950 [NCBI, ExPASy, EBI, Israel, Japan]
Li X.,
Gerber S.A.,
Rudner A.D.,
Beausoleil S.A.,
Haas W.,
Villen J.,
Elias J.E.,
Gygi S.P.;
"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.";
J. Proteome Res. 6:1190-1197(2007).
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[15]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-770, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0607084104; PubMed=17287358 [NCBI, ExPASy, EBI, Israel, Japan]
Chi A.,
Huttenhower C.,
Geer L.Y.,
Coon J.J.,
Syka J.E.P.,
Bai D.L.,
Shabanowitz J.,
Burke D.J.,
Troyanskaya O.G.,
Hunt D.F.;
"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.";
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007).
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[16]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-519; THR-735 AND SER-770, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0701622104; PubMed=17563356 [NCBI, ExPASy, EBI, Israel, Japan]
Smolka M.B.,
Albuquerque C.P.,
Chen S.H.,
Zhou H.;
"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.";
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
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[17]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-292; SER-318; SER-423; SER-472; SER-519; SER-599; THR-735 AND SER-770, AND MASS SPECTROMETRY.
DOI=10.1074/mcp.M700468-MCP200; PubMed=18407956 [NCBI, ExPASy, EBI, Israel, Japan]
Albuquerque C.P.,
Smolka M.B.,
Payne S.H.,
Bafna V.,
Eng J.,
Zhou H.;
"A multidimensional chromatography technology for in-depth phosphoproteome analysis.";
Mol. Cell. Proteomics 7:1389-1396(2008).
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