ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P24040

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name NIRS_PSEST
Primary accession number P24040
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 1992
Sequence was last modified on March 1, 1992 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 65)
Name and origin of the protein
Protein name Nitrite reductase [Precursor]
Synonyms EC 1.7.2.1
Cytochrome cd1
Cytochrome oxidase
Hydroxylamine reductase
EC 1.7.99.1
Gene name
Name: nirS
From
Pseudomonas stutzeri (Pseudomonas perfectomarina) [TaxID: 316] 
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
STRAIN=ATCC 14405 / 218 / ZoBell;
DOI=10.1016/0014-5793(91)80150-2; PubMed=2001732 [NCBI, ExPASy, EBI, Israel, Japan]
Juengst A., Wakabayashi S., Matsubara H., Zumft W.G.;
"The nirSTBM region coding for cytochrome cd1-dependent nitrite respiration of Pseudomonas stutzeri consists of a cluster of mono-, di-, and tetraheme proteins.";
FEBS Lett. 279:205-209(1991).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X53676; CAA40150.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S13613; OSPSZ.
3D structure databases
HSSP P24474; 1GJQ. [HSSP ENTRY / PDB]
ModBase P24040.
Enzyme and pathway databases
BioCyc MetaCyc:MON-201; -.
Ontologies
GO
GO:0042597; Cellular component: periplasmic space (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0050418; Molecular function: hydroxylamine reductase activity (inferred from electronic annotation from EC).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from InterPro).
GO:0050421; Molecular function: nitrite reductase (NO-forming) activity (inferred from electronic annotation from InterPro).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0046209; Biological process: nitric oxide metabolic process (inferred from electronic annotation from InterPro).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR009056; Cyt_c_monohaem.
IPR003143; Cyt_d1_haem.
Graphical view of domain structure.
Gene3D G3DSA:2.140.10.20; Cyt_d1_haem; 1.
G3DSA:1.10.760.10; Cytochrome_c_R; 1.
Pfam PF02239; Cytochrom_D1; 1.
Pfam graphical view of domain structure.
PROSITE PS51007; CYTC; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet P24040.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Direct protein sequencing; Electron transport; Heme; Iron; Metal-binding; Oxidoreductase; Periplasm; Signal; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    26  26      
CHAIN   27   560  534     Nitrite reductase. PRO_0000006577
DOMAIN   30   126  97     Cytochrome c. 
REGION   27    29  3     N-terminal tail. 
REGION   127   560  434     D1-heme domain. 
METAL   51    51        Iron (heme axial ligand) (By similarity). 
METAL   101   101        Iron (heme axial ligand) (By similarity). 
METAL   193   193        Iron (heme D1 proximal ligand) (By similarity). 
BINDING   47    47        Heme (covalent) (By similarity). 
BINDING   50    50        Heme (covalent) (By similarity). 
Sequence information
Length: 560 AA [This is the length of the unprocessed precursor] Molecular weight: 61993 Da [This is the MW of the unprocessed precursor] CRC64: 476259C35FBFA7A0 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSNVGKPILA GLIAGLSLLG LAVAQAAAPE MTAEEKEASK QIYFERCAGC HGVLRKGATG 

        70         80         90        100        110        120 
KNLEPHWSKT EADGKKTEGG TLNLGTKRLE NIIAYGTEGG MVNYDDILTK EEINMMARYI 

       130        140        150        160        170        180 
QHTPDIPPEF SLQDMKDSWN LIVPVEKRVT KQMNKINLQN VFAVTLRDAG KLALIDGDTH 

       190        200        210        220        230        240 
KIWKVLESGY AVHISRMSAS GRYVYTTGRD GLTTIIDLWP EEPMTVATVR FGSDMRSVDV 

       250        260        270        280        290        300 
SKFEGYEDKY LIGGTYWPPQ YSIVDGLTLE PIKVVSTRGQ TVDGEYHPEP RVASIVASHI 

       310        320        330        340        350        360 
KPEWVVNVKE TGQIILVDYT DLKNLKTTTI ESAKFLHDGG WDYSKRYFMV AANASNKVAA 

       370        380        390        400        410        420 
VDTKTGKLAA LIDTAKIPHP GRGANFVHPQ FGPVWSTGHL GDDVVSLIST PSEESKYAKY 

       430        440        450        460        470        480 
KEHNWKVVQE LKMPGAGNLF VKTHPKSKHF WADAPMNPER EVAESVYVFD MNDLSKAPIQ 

       490        500        510        520        530        540 
LNVAKDSGLP ESKAIRRAVQ PEYNKAGDEV WISLWGGKTD QSAIVIYDDK TLKLKRVITD 

       550        560 
PAVVTPTGKF NVFNTMNDVY
P24040 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!