[1]
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NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE, ALTERNATIVE SPLICING, AND FUNCTION.
TISSUE=Fetal brain;
PubMed=8449401 [NCBI, ExPASy, EBI, Israel, Japan]
Patton J.G.,
Porro E.B.,
Galceran J.,
Tempst P.,
Nadal-Ginard B.;
"Cloning and characterization of PSF, a novel pre-mRNA splicing factor.";
Genes Dev. 7:393-406(1993).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature04727; PubMed=16710414 [NCBI, ExPASy, EBI, Israel, Japan]
Gregory S.G.,
Barlow K.F.,
McLay K.E.,
Kaul R.,
Swarbreck D.,
Dunham A.,
Scott C.E.,
Howe K.L.,
Woodfine K.,
Spencer C.C.A.,
Jones M.C.,
Gillson C.,
Searle S.,
Zhou Y.,
Kokocinski F.,
McDonald L.,
Evans R.,
Phillips K.,
Atkinson A., ![]()
Cooper R.,
Jones C.,
Hall R.E.,
Andrews T.D.,
Lloyd C.,
Ainscough R.,
Almeida J.P.,
Ambrose K.D.,
Anderson F.,
Andrew R.W.,
Ashwell R.I.S.,
Aubin K.,
Babbage A.K.,
Bagguley C.L.,
Bailey J.,
Beasley H.,
Bethel G.,
Bird C.P.,
Bray-Allen S.,
Brown J.Y.,
Brown A.J.,
Buckley D.,
Burton J.,
Bye J.,
Carder C.,
Chapman J.C.,
Clark S.Y.,
Clarke G.,
Clee C.,
Cobley V.,
Collier R.E.,
Corby N.,
Coville G.J.,
Davies J.,
Deadman R.,
Dunn M.,
Earthrowl M.,
Ellington A.G.,
Errington H.,
Frankish A.,
Frankland J.,
French L.,
Garner P.,
Garnett J.,
Gay L.,
Ghori M.R.J.,
Gibson R.,
Gilby L.M.,
Gillett W.,
Glithero R.J.,
Grafham D.V.,
Griffiths C.,
Griffiths-Jones S.,
Grocock R.,
Hammond S.,
Harrison E.S.I.,
Hart E.,
Haugen E.,
Heath P.D.,
Holmes S.,
Holt K.,
Howden P.J.,
Hunt A.R.,
Hunt S.E.,
Hunter G.,
Isherwood J.,
James R.,
Johnson C.,
Johnson D.,
Joy A.,
Kay M.,
Kershaw J.K.,
Kibukawa M.,
Kimberley A.M.,
King A.,
Knights A.J.,
Lad H.,
Laird G.,
Lawlor S.,
Leongamornlert D.A.,
Lloyd D.M.,
Loveland J.,
Lovell J.,
Lush M.J.,
Lyne R.,
Martin S.,
Mashreghi-Mohammadi M.,
Matthews L.,
Matthews N.S.W.,
McLaren S.,
Milne S.,
Mistry S.,
Moore M.J.F.,
Nickerson T.,
O'Dell C.N.,
Oliver K.,
Palmeiri A.,
Palmer S.A.,
Parker A.,
Patel D.,
Pearce A.V.,
Peck A.I.,
Pelan S.,
Phelps K.,
Phillimore B.J.,
Plumb R.,
Rajan J.,
Raymond C.,
Rouse G.,
Saenphimmachak C.,
Sehra H.K.,
Sheridan E.,
Shownkeen R.,
Sims S.,
Skuce C.D.,
Smith M.,
Steward C.,
Subramanian S.,
Sycamore N.,
Tracey A.,
Tromans A.,
Van Helmond Z.,
Wall M.,
Wallis J.M.,
White S.,
Whitehead S.L.,
Wilkinson J.E.,
Willey D.L.,
Williams H.,
Wilming L.,
Wray P.W.,
Wu Z.,
Coulson A.,
Vaudin M.,
Sulston J.E.,
Durbin R.M.,
Hubbard T.,
Wooster R.,
Dunham I.,
Carter N.P.,
McVean G.,
Ross M.T.,
Harrow J.,
Olson M.V.,
Beck S.,
Rogers J.,
Bentley D.R.;
"The DNA sequence and biological annotation of human chromosome 1.";
Nature 441:315-321(2006).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J.,
Istrail S.,
Sutton G.G.,
Florea L.,
Halpern A.L.,
Mobarry C.M.,
Lippert R.,
Walenz B.,
Shatkay H.,
Dew I.,
Miller J.R.,
Flanigan M.J.,
Edwards N.J.,
Bolanos R.,
Fasulo D.,
Halldorsson B.V.,
Hannenhalli S.,
Turner R.,
Yooseph S., ![]()
Lu F.,
Nusskern D.R.,
Shue B.C.,
Zheng X.H.,
Zhong F.,
Delcher A.L.,
Huson D.H.,
Kravitz S.A.,
Mouchard L.,
Reinert K.,
Remington K.A.,
Clark A.G.,
Waterman M.S.,
Eichler E.E.,
Adams M.D.,
Hunkapiller M.W.,
Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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[4]
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PROTEIN SEQUENCE OF 48-68 AND 213-246, BLOCKAGE OF N-TERMINUS, DNA-BINDING, AND SUBUNIT.
PubMed=8439294 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang W.-W.,
Zhang L.-X.,
Busch R.K.,
Farres J.,
Busch H.;
"Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells.";
Biochem. J. 290:267-272(1993).
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[5]
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PROTEIN SEQUENCE OF 292-311; 415-421 AND 503-510, AND IDENTIFICATION IN U5/4/6 SNRNP COMPLEXES.
PubMed=9409622 [NCBI, ExPASy, EBI, Israel, Japan]
Teigelkamp S.,
Mundt C.,
Achsel T.,
Will C.L.,
Luehrmann R.;
"The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p.";
RNA 3:1313-1326(1997).
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[6]
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NUCLEOTIDE SEQUENCE [MRNA] OF 312-707.
TISSUE=Fetal skeletal muscle;
PubMed=2480877 [NCBI, ExPASy, EBI, Israel, Japan]
Gower H.J.,
Moore S.E.,
Dickson G.,
Elsom V.L.,
Nayak R.,
Walsh F.S.;
"Cloning and characterization of a myoblast cell surface antigen defined by 24.1D5 monoclonal antibody.";
Development 105:723-731(1989).
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[7]
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PROTEIN SEQUENCE OF 414-421 AND 427-448, SUBCELLULAR LOCATION, INTERACTION WITH SNRPA, AND IDENTIFICATION IN A SNRNP-FREE COMPLEX WITH SNRPA.
DOI=10.1017/S1355838298981183; PubMed=9848648 [NCBI, ExPASy, EBI, Israel, Japan]
Lutz C.S.,
Cooke C.,
O'Connor J.P.,
Kobayashi R.,
Alwine J.C.;
"The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor.";
RNA 4:1493-1499(1998).
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[8]
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PROTEIN SEQUENCE OF 600-606 AND 667-677, INTERACTION WITH PTBP1, AND SUBCELLULAR LOCATION.
DOI=10.1002/(SICI)1097-4644(20000315)76:4<559::AID-JCB4>3.3.CO;2-L; PubMed=10653975 [NCBI, ExPASy, EBI, Israel, Japan]
Meissner M.,
Dechat T.,
Gerner C.,
Grimm R.,
Foisner R.,
Sauermann G.;
"Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB.";
J. Cell. Biochem. 76:559-566(2000).
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[9]
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FUNCTION, INTERACTION WITH PRE-MRNA, AND IDENTIFICATION IN SPLICEOSOME COMPLEX.
PubMed=8045264 [NCBI, ExPASy, EBI, Israel, Japan]
Gozani O.,
Patton J.G.,
Reed R.;
"A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction.";
EMBO J. 13:3356-3367(1994).
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[10]
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CHROMOSOMAL TRANSLOCATION WITH TFE3.
DOI=10.1038/sj.onc.1201394; PubMed=9393982 [NCBI, ExPASy, EBI, Israel, Japan]
Clark J.,
Lu Y.-J.,
Sidhar S.K.,
Parker C.,
Gill S.,
Smedley D.,
Hamoudi R.,
Linehan W.M.,
Shipley J.,
Cooper C.S.;
"Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma.";
Oncogene 15:2233-2239(1997).
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[11]
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INTERACTION WITH TOP1, AND IDENTIFICATION IN A COMPLEX WITH NONO AND TOP1.
DOI=10.1074/jbc.273.41.26261; PubMed=9756848 [NCBI, ExPASy, EBI, Israel, Japan]
Straub T.,
Grue P.,
Uhse A.,
Lisby M.,
Knudsen B.R.,
Tange T.O.,
Westergaard O.,
Boege F.;
"The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction.";
J. Biol. Chem. 273:26261-26264(1998).
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[12]
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FUNCTION IN DNA UNWINDING.
DOI=10.1021/bi992898e; PubMed=10858305 [NCBI, ExPASy, EBI, Israel, Japan]
Straub T.,
Knudsen B.R.,
Boege F.;
"PSF/p54(nrb) stimulates 'jumping' of DNA topoisomerase I between separate DNA helices.";
Biochemistry 39:7552-7558(2000).
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[13]
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FUNCTION IN TRANSCRIPTION REGULATION, AND IDENTIFICATION BY MASS SPECTROMETRY.
DOI=10.1210/me.14.6.774; PubMed=10847580 [NCBI, ExPASy, EBI, Israel, Japan]
Urban R.J.,
Bodenburg Y.,
Kurosky A.,
Wood T.G.,
Gasic S.;
"Polypyrimidine tract-binding protein-associated splicing factor is a negative regulator of transcriptional activity of the porcine p450scc insulin-like growth factor response element.";
Mol. Endocrinol. 14:774-782(2000).
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[14]
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FUNCTION IN HOMOLOGOUS DNA PAIRING, AND PHOSPHORYLATION.
DOI=10.1093/nar/28.16.3022; PubMed=10931916 [NCBI, ExPASy, EBI, Israel, Japan]
Akhmedov A.T.,
Lopez B.S.;
"Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion.";
Nucleic Acids Res. 28:3022-3030(2000).
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[15]
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FUNCTION IN NUCLEAR RETENTION OF A-TO-I EDITED RNAS, AND IDENTIFICATION IN A COMPLEX WITH NONO AND MATR3.
DOI=10.1016/S0092-8674(01)00466-4; PubMed=11525732 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang Z.,
Carmichael G.G.;
"The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs.";
Cell 106:465-475(2001).
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[16]
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INTERACTION WITH SNRP70, AND PHOSPHORYLATION.
PubMed=11514619 [NCBI, ExPASy, EBI, Israel, Japan]
Shav-Tal Y.,
Cohen M.,
Lapter S.,
Dye B.,
Patton J.G.,
Vandekerckhove J.,
Zipori D.;
"Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions.";
Mol. Biol. Cell 12:2328-2340(2001).
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[17]
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FUNCTION IN TRANSCRIPTION REGULATION, AND INTERACTION WITH RXRA; THRA AND SIN3A.
DOI=10.1128/MCB.21.7.2298-2311.2001; PubMed=11259580 [NCBI, ExPASy, EBI, Israel, Japan]
Mathur M.,
Tucker P.W.,
Samuels H.H.;
"PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.";
Mol. Cell. Biol. 21:2298-2311(2001).
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[18]
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FUNCTION IN TRANSCRIPTION REGULATION, INTERACTION WITH NR5A1 AND SIN3A, AND IDENTIFICATION IN A COMPLEX WITH NONO AND NR5A1.
DOI=10.1210/en.143.4.1280; PubMed=11897684 [NCBI, ExPASy, EBI, Israel, Japan]
Sewer M.B.,
Nguyen V.Q.,
Huang C.J.,
Tucker P.W.,
Kagawa N.,
Waterman M.R.;
"Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription.";
Endocrinology 143:1280-1290(2002).
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[19]
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INTERACTION WITH NONO AND U5 SNRNA, AND IDENTIFICATION IN IN U5/4/6 SNRNP SND SPLICEOSOME COMPLEXES.
DOI=10.1017/S1355838202022070; PubMed=12403470 [NCBI, ExPASy, EBI, Israel, Japan]
Peng R.,
Dye B.T.,
Perez I.,
Barnard D.C.,
Thompson A.B.,
Patton J.G.;
"PSF and p54nrb bind a conserved stem in U5 snRNA.";
RNA 8:1334-1347(2002).
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[20]
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METHYLATION [LARGE SCALE ANALYSIS] AT ARG-7; ARG-9; ARG-19 AND ARG-25, AND MASS SPECTROMETRY.
DOI=10.1038/nmeth715; PubMed=15782174 [NCBI, ExPASy, EBI, Israel, Japan]
Ong S.E.,
Mittler G.,
Mann M.;
"Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.";
Nat. Methods 1:119-126(2004).
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[21]
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FUNCTION IN DNA REPAIR, IDENTIFICATION BY MASS SPECTROMETRY, DNA-BINDING, AND SUBUNIT.
DOI=10.1074/jbc.M412758200; PubMed=15590677 [NCBI, ExPASy, EBI, Israel, Japan]
Bladen C.L.,
Udayakumar D.,
Takeda Y.,
Dynan W.S.;
"Identification of the polypyrimidine tract binding protein-associated splicing factor.p54(nrb) complex as a candidate DNA double-strand break rejoining factor.";
J. Biol. Chem. 280:5205-5210(2005).
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[22]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-33, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
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[23]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-687, AND MASS SPECTROMETRY.
DOI=10.1021/pr0705441; PubMed=18220336 [NCBI, ExPASy, EBI, Israel, Japan]
Cantin G.T.,
Yi W.,
Lu B.,
Park S.K.,
Xu T.,
Lee J.-D.,
Yates J.R. III;
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.";
J. Proteome Res. 7:1346-1351(2008).
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