ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P22699


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name GUN6_DICDI
Primary accession number P22699
Secondary accession number Q55BI5
Integrated into Swiss-Prot on August 1, 1991
Sequence was last modified on August 1, 1991 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 60)
Name and origin of the protein
Protein name Endoglucanase [Precursor]
Synonyms EC 3.2.1.4
Endo-1,4-beta-glucanase
Spore germination protein 270-6
Cellulase
Gene name
Name: celA
ORFNames: DDB_G0271134
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1021/bi00483a015; PubMed=1976383 [NCBI, ExPASy, EBI, Israel, Japan]
Giorda R., Ohmachi T., Shaw D.R., Ennis H.L.;
"A shared internal threonine-glutamic acid-threonine-proline repeat defines a family of Dictyostelium discoideum spore germination specific proteins.";
Biochemistry 29:7264-7269(1990).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
[3]
FUNCTION.
PubMed=1869562 [NCBI, ExPASy, EBI, Israel, Japan]
Blume J.E., Ennis H.L.;
"A Dictyostelium discoideum cellulase is a member of a spore germination-specific gene family.";
J. Biol. Chem. 266:15432-15437(1991).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M33861; AAA52077.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAFI02000006; EAL71697.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A35621; A35621.
RefSeq XP_645627.1; -.
3D structure databases
HSSP Q9EYQ2; 1IA6. [HSSP ENTRY / PDB]
ModBase P22699.
Organism-specific databases
dictyBase DDB0215351; celA.
Ontologies
GO
GO:0008810; Molecular function: cellulase activity (inferred from electronic annotation from EC).
GO:0030245; Biological process: cellulose catabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0030435; Biological process: sporulation resulting in formation of a cellular spore (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR012341; 6hp_glycosidase.
IPR001701; Glyco_hydro_9.
Graphical view of domain structure.
Gene3D G3DSA:1.50.10.10; CelA/Cel48F_cat; 1.
PANTHER PTHR22298:SF3; Glyco_hydro_9; 1.
Pfam PF00759; Glyco_hydro_9; 1.
Pfam graphical view of domain structure.
PROSITE PS00592; GLYCOSYL_HYDROL_F9_1; 1.
PS00698; GLYCOSYL_HYDROL_F9_2; 1.
ProtoNet P22699.
Genome annotation databases
GeneID 3396769; -.
KEGG ddi:DDB_0215351; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Cellulose degradation; Complete proteome; Glycoprotein; Glycosidase; Hydrolase; Polysaccharide degradation; Repeat; Signal; Sporulation.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    23  23     Potential. 
CHAIN   24   705  682     Endoglucanase. PRO_0000007953
REGION   463   552  90     Pro/Thr repeats ("hinge") (Pro/Thr box). 
ACT_SITE   390   390        By similarity. 
ACT_SITE   428   428        By similarity. 
ACT_SITE   437   437        By similarity. 
CARBOHYD   75    75        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 705 AA [This is the length of the unprocessed precursor] Molecular weight: 75911 Da [This is the MW of the unprocessed precursor] CRC64: F0457BDC07576A15 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKILKNCILL IIFGLLSTQL INADTDYCSL LENALMFYKM NRAGRLPDND IPWRGNSALN 

        70         80         90        100        110        120 
DASPNSAKDA NGDGNLSGGY FDAGDGVKFG LPMAYSMTML GWSFIEYESN IAQCGLTSLY 

       130        140        150        160        170        180 
LDTIKYGTDW LIAAHTADNE FAGQVGDGNV DHSWWGPPED MTMARPTYML TTEAPGTEIA 

       190        200        210        220        230        240 
MEAASALAAA SIAFKSSNPT YAATCLAHAK TLHNFGYTYR GVYSDSITNA QAFYNSWSGY 

       250        260        270        280        290        300 
KDDLVWGSIW LYKATQDSDY LTKAVADYAS GGVGGMAQGN SHDWDNKAPG CCLLLSKLVP 

       310        320        330        340        350        360 
TTSTYKTDFE GWLNYWLPGG GVTYTPGGLA WIRQWGPARY AATAAFLGSL AGTEKGTDFT 

       370        380        390        400        410        420 
QKQVDYLIGN NPNQQSFVVG MGPNYPINPH HRAAHHSTTN DINNPVNNLY LLKGALVGGP 

       430        440        450        460        470        480 
GSNDEYTDDR TDYISNEVAT DYNAGFVGAL ASLVNPSSTS VPTTTPTVTE TPTETPTETP 

       490        500        510        520        530        540 
TETPTETPTE TPTETPTETP TETPTETPTE TPTETPTETP TETPTETPTE TPTETPTETV 

       550        560        570        580        590        600 
TPTPTVTPTE TPSSGESLSI YKSGLKNDFQ DWSWGEHSLT DTTNVESGET NSISFTPKAY 

       610        620        630        640        650        660 
GAVFLGCFEC IDTDTYNNIE FDINGGSSGA QLLRITVVKN SKSVGSKLIT DLNGGTPIEA 

       670        680        690        700 
NSWTKIKASF IDDFKVSGKV DGIWIQDIKG DTQSTVYISN IIATA 

P22699 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ch flag SIB Switzerland Mirror sites: Australia  Brazil  Canada  China  Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!